Abstract: An orthodontic appliance includes a body. The body includes a first portion defining a slot for receiving an archwire. The body further includes a second portion extending from the first portion along a longitudinal axis. The second portion includes a bottom surface opposite to the first portion. The second portion further includes a lateral surface extending from the bottom surface towards the first portion along the longitudinal axis. The bottom surface and the lateral surface at least partially form an external surface of the body. The second portion defines a cavity at least partially surrounded by the bottom surface. The cavity at least partially extends along a length of the second portion from the bottom surface. The cavity includes a reservoir and at least one passage disposed in fluid communication with the reservoir. The at least one passage extends from the reservoir to the lateral surface.

Abstract: Attachments of the present disclosure combines the optimal practices of the traditional bracket-wire system and more recent resilient appliance (e.g., CTAs and polymeric bands) systems. The attachments include prescribed in/outs, torques and angulations designed utilizing the straight wire methodology for determining the bonding location on a particular tooth of the dental arch. A marriage of bracket prescription with attachment placement can help the treating professional to better visualize the treatment outcome with the tray or band on the patient.

Abstract: Orthodontic appliances, methods of preparing and seating said orthodontic appliances, and kits including said orthodontic appliances are described.

Abstract: A method includes wire driven phase in which a plurality of attachments are bonded to teeth, the attachments including a wire-retaining region and an engagement region. The engagement region has a shoulder configured to releasably engage a corresponding indentation in an aligner tray. An archwire is inserted in to the wire-retaining regions to move a first malaccluded tooth from a first position to a second position. An aligner phase follows the wire driven phase, in which the archwire is removed, and an aligner tray is applied over the teeth of the patient. The aligner tray includes cavities shaped to receive and resiliently position the first maloccluded tooth from the second position to a third position, and further includes indentations configured to releasably engage at least a portion of the engagement regions on the attachments.

Abstract: Attachments of the present disclosure combines the optimal practices of the traditional bracket-wire system and more recent resilient appliance (e.g., CTAs and polymeric bands) systems. The attachments include prescribed in/outs, torques and angulations designed utilizing the straight wire methodology for determining the bonding location on a particular tooth of the dental arch. A marriage of bracket prescription with attachment placement can help the treating professional to better visualize the treatment outcome with the tray or band on the patient.

Abstract: The present disclosure provides high strength, self-ligating appliances with orthodontically desirable dimensions. The appliances of the present disclosure incorporate a door slidably engaged to a channel in the body; one that can be opened or closed depending on the equilibrium position of an integral protrusion on the door. Cooperating grooves and rails on the body and the door can guide the door between the open and closed positions, and mitigate against unintentional detachment.

Abstract: A door handle set includes a handle assembly having a primary lock and having a handle rotatable about a primary rotational axis. A latch bolt assembly has a latch bolt. The latch bolt assembly is operatively coupled to the handle assembly, wherein a rotation of the handle results in a linear translation of the latch bolt. A supplemental lock has a second axis parallel to, and spaced apart from, the primary rotational axis. The supplemental lock has an actuator that is operable relative to the second axis. The supplemental lock is configured to selectively block the rotation of the handle regardless of the locking state of the primary lock.

Abstract: The present disclosure provides high strength, self-ligating appliances with orthodontically desirable dimensions. The appliances of the present disclosure incorporate a door slidably engaged to a channel in the body; one that can be opened or closed depending on the equilibrium position of an integral protrusion on the door. Cooperating grooves and rails on the body and the door can guide the door between the open and closed positions and mitigate against unintentional detachment.

Abstract: The present disclosure provides high strength, self-ligating appliances with orthodontically desirable dimensions. The appliances of the present disclosure incorporate a door slidably engaged to a channel in the body; one that can be opened or closed depending on the equilibrium position of an integral protrusion on the door. Cooperating grooves and rails on the body and the door can guide the door between the open and closed positions, and mitigate against unintentional detachment.

Abstract: Continuous adjustment appliances are provided that can store a large number of geometries that can be successively accessed throughout orthodontic treatment, with each geometry can correspond to an arrangement of the patient's teeth. An appliance according to the present disclosure can be stimulated to transition among the myriad geometries, which can include changes to the overall shape of the appliance as well as the position and geometry of the cavities corresponding to a patient's teeth. Methods of creating the continuous adjustment appliances and methods of treatment using the continuous adjustment appliances are also revealed.

Abstract: A high-strength, self-ligating appliances with orthodontically desirable dimensions. The appliances incorporate a door slidably engaged to a channel in the body; one that can be opened or closed depending on the equilibrium position of an integral protrusion on the door. Cooperating grooves and rails on the body and the door can guide the door between the open and closed positions, and mitigate against unintentional detachment. Appliances including rails that result in improved labial pull strength are disclosed.

Abstract: A high-strength, self-ligating appliances with orthodontically desirable dimensions. The appliances incorporate a door slidably engaged to a channel in the body; one that can be opened or closed depending on the equilibrium position of an integral protrusion on the door. Cooperating grooves and rails on the body and the door can guide the door between the open and closed positions, and mitigate against unintentional detachment. Appliances including rails that result in improved labial pull strength are disclosed.

Abstract: A twisting-action, sliding bracket-door opening tool including a ceramic blade for opening self-ligating brackets, particularly ceramic self-ligating brackets with ceramic doors. The ceramic tool blade allows for opening of the ceramic bracket sliding door without significant wear or function loss, as compared to a similar tool made of stainless steel.

Abstract: Continuous adjustment appliances are provided that can store a large number of geometries that can be successively accessed throughout orthodontic treatment, with each geometry can correspond to an arrangement of the patient's teeth. An appliance according to the present disclosure can be stimulated to transition among the myriad geometries, which can include changes to the overall shape of the appliance as well as the position and geometry of the cavities corresponding to a patient's teeth. Methods of creating the continuous adjustment appliances and methods of treatment using the continuous adjustment appliances are also revealed.

Abstract: The invention relates to the expansion of T cells and particularly, although not exclusively, to the expansion of gamma delta T cells, and the optimization of medium, serum and cytokine combinations for large-scale ex vivo expansion of gamma delta T cells for clinical use.

Abstract: The present disclosure provides high strength, self-ligating appliances with orthodontically desirable dimensions. The appliances of the present disclosure incorporate a door slidably engaged to a channel in the body; one that can be opened or closed depending on the equilibrium position of an integral protrusion on the door. Cooperating grooves and rails on the body and the door can guide the door between the open and closed positions, and mitigate against unintentional detachment.

Abstract: Continuous adjustment appliances are provided that can store a large number of geometries that can be successively accessed throughout orthodontic treatment, with each geometry can correspond to an arrangement of the patient's teeth. An appliance according to the present disclosure can be stimulated to transition among the myriad geometries, which can include changes to the overall shape of the appliance as well as the position and geometry of the cavities corresponding to a patient's teeth. Methods of creating the continuous adjustment appliances and methods of treatment using the continuous adjustment appliances are also revealed.

Abstract: Appliances and related methods use a resilient retention member that is retained in a recess within a body that is optionally made from a suitably translucent ceramic material. The retention member, optionally in combination with one or more side walls of the recess, provides two or more regions for accommodating a protrusion. The protrusion, in turn, is part of a sliding door which can be opened or closed depending on the equilibrium position of the protrusion with respect to the two or more regions. Based on the engagement between the protrusion and the retention member, these appliances can provide discrete opened and closed door positions to facilitate archwire ligation.

Abstract: Provided is an orthodontic splint and related methods, which use two or more bonding pads and a flexible connector beam that deflects in response to stress, effectively reducing the amount of stress felt by the adhesive. The connector beam has a non-uniform cross-section along its length, thereby shifting the maximum stress away from the ends of the beam and toward the midpoint of the beam. Further, the connector beam attached to each base along locations remote from the outer edge of the base. These splint configurations can decrease the likelihood of bond failure and improve fatigue performance by causing stress, and associated strain, encountered during treatment to be spread more evenly along the length of the beam.

Abstract: The present invention relates to a disposable heating cup intended for heating up a food product or for maintaining such a food product when pre-heated hot in a disposable cup over an extended period of time, wherein the heating cup is characterized in that it comprises a printed electrical heating circuit and a printed USB connector linked to said electrical heating circuit. Furthermore, the present invention relates to a packaged food product comprising the disposable heating cup, and a method for heating a food or beverage product with making use of a disposable heating cup.