Patents by Inventor Lance Fors

Lance Fors has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for analyzing nucleic acid
    Patent number: 7824862
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: November 2, 2010
    Assignee: Third Wave Technologies, Inc.
    Inventors: Fang Dong, Victor I. Lyamichev, James R. Prudent, Lance Fors, Bruce P. Neri, Mary Ann D. Brow, Todd A. Anderson, James E. Dahlberg
  • METHODS FOR ANALYZING NUCLEIC ACID
    Publication number: 20090117576
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Application
    Filed: September 30, 2008
    Publication date: May 7, 2009
    Applicant: THIRD WAVE TECHNOLOGIES, INC.
    Inventors: Fang Dong, Victor I. Lyamichev, James R. Prudent, Lance Fors, Bruce P. Neri, Mary Ann D. Brow, Todd A. Anderson, James E. Dahlberg
  • Methods for genotyping hepatitis C virus
    Patent number: 7429455
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: September 5, 2006
    Date of Patent: September 30, 2008
    Assignee: Third Wave Technologies, Inc.
    Inventors: Fang Dong, Victor I. Lyamichev, James R. Prudent, Lance Fors, Bruce P. Neri, Mary Ann D. Brow, Todd A. Anderson, James E. Dahlberg
  • Nucleic acid detection in pooled samples
    Publication number: 20080015112
    Abstract: The present invention relates to detecting target nucleic acid sequences in pooled samples. In particular, the present invention relates to compositions and methods for detecting the presence or absence of target nucleic acid sequences (e.g. RNA virus sequences) in a pooled sample employing an INVADER detection assay. In certain embodiments, the present invention allows target nucleic acid sequence detection in pooled biological samples (e.g. pooled blood samples) without prior amplification of the target.
    Type: Application
    Filed: February 15, 2006
    Publication date: January 17, 2008
    Inventors: Lance Fors, Bruce Neri, Mary Brow, Monika Indig, Robert Roeven
  • Methods for genotyping hepatitis C virus
    Publication number: 20070065815
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Application
    Filed: September 5, 2006
    Publication date: March 22, 2007
    Inventors: Fang Dong, Victor Lyamichev, James Prudent, Lance Fors, Bruce Neri, Mary Brow, Todd Anderson, James Dahlberg
  • Target-dependent reactions using structure-bridging oligonucleotides
    Patent number: 7101672
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acids and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: September 4, 2003
    Date of Patent: September 5, 2006
    Assignee: Third Wave Technologies, Inc.
    Inventors: Fang Dong, Victor I. Lyamichev, James R. Prudent, Lance Fors, Bruce P. Neri, Mary Ann D. Brow, Todd A. Anderson, James E. Dahlberg
  • Combination therapies of cicletanine and carvedilol
    Publication number: 20060154959
    Abstract: Preferred embodiments of the present invention are related to novel therapeutic drug combinations and methods for treating and/or preventing hypertension and complications in patients with diabetes and/or metabolic syndrome. More particularly, aspects of the present invention are related to using a combination of cicletanine and carvedilol for treating and/or preventing hypertension and complications in patients with diabetes and/or metabolic syndrome.
    Type: Application
    Filed: January 13, 2005
    Publication date: July 13, 2006
    Inventors: Glenn Cornett, Michael Hensley, Lance Fors
  • Combination therapies of cicletanine and magnesium
    Publication number: 20060153934
    Abstract: Preferred embodiments of the present invention are related to novel therapeutic drug combinations and methods for treating and/or preventing hypertension and complications in patients with diabetes and/or metabolic syndrome. More particularly, aspects of the present invention are related to using a combination of cicletanine and magnesium for treating and/or preventing hypertension and complications in patients with diabetes and/or metabolic syndrome.
    Type: Application
    Filed: January 13, 2005
    Publication date: July 13, 2006
    Inventors: Glenn Cornett, Michael Hensley, Lance Fors
  • Combination therapies of cicletanine and lacidipine
    Publication number: 20060154971
    Abstract: Preferred embodiments of the present invention are related to novel therapeutic drug combinations and methods for treating and/or preventing hypertension and complications in patients with diabetes and/or metabolic syndrome. More particularly, aspects of the present invention are related to using a combination of cicletanine and lacidipine (a preferred calcium antagonist) for treating and/or preventing hypertension and complications in patients with diabetes and/or metabolic syndrome.
    Type: Application
    Filed: January 13, 2005
    Publication date: July 13, 2006
    Inventors: Glenn Cornett, Michael Hensley, Lance Fors
  • Target-dependent reactions using structure-bridging oligonucleotides
    Publication number: 20050014163
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acids and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Application
    Filed: September 4, 2003
    Publication date: January 20, 2005
    Inventors: Fang Dong, Victor Lyamichev, James Prudent, Lance Fors, Bruce Neri, Mary Ann Brow, Todd Anderson, James Dahlberg
  • Polymorphism analysis by nucleic and acid structure probing
    Patent number: 6780585
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: August 24, 2004
    Assignee: Third Wave Technologies, Inc.
    Inventors: Fang Dong, Victor I. Lyamichev, James R. Prudent, James E. Dahlberg, Lance Fors
  • Target-dependent reactions using structure-bridging oligonucleotides
    Patent number: 6709815
    Abstract: The present invention relates to methods and compns. for treating nucleic acids, and in particular, methods and compns. for the detection and characterization of nucleic acid sequences and sequence changes. The invention provides methods for examg. the conformations assumed by single strands of nucleic acid, forming the basis of novel methods of detection of specific nucleic acid sequences. The present invention contemplates use of novel detection methods for, among other uses, clinical diagnostic purposes, including but not limited to the detection and identification of pathogenic organisms. Examples are presented for the analysis of Mycobacterium tuberculosis and hepatitis C virus genes.
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: March 23, 2004
    Assignee: Third Wave Technologies, Inc.
    Inventors: Fang Dong, Victor I. Lyamichev, James R. Prudent, Lance Fors, Bruce P. Neri, Mary Ann D. Brow, Todd A. Anderson, James E. Dahlberg
  • Polymorphism analysis by nucleic acid structure probing with structure-bridging oligonucleotides
    Patent number: 6709819
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: March 23, 2004
    Assignee: Third Wave Technologies, Inc.
    Inventors: Victor I. Lyamichev, Fang Dong, Mary Ann D. Brow, Lance Fors, Bruce P. Neri
  • Nucleic acid detection in pooled samples
    Publication number: 20030152942
    Abstract: The present invention relates to detecting target nucleic acid sequences in pooled samples. In particular, the present invention relates to compositions and methods for detecting the presence or absence of target nucleic acid sequences (e.g. RNA virus sequences) in a pooled sample employing an INVADER detection assay. In certain embodiments, the present invention allows target nucleic acid sequence detection in pooled biological samples (e.g. pooled blood samples) without prior amplification of the target.
    Type: Application
    Filed: May 9, 2002
    Publication date: August 14, 2003
    Inventors: Lance Fors, Bruce P. Neri, Mary Ann D. Brow, Monika de Arruda Indig, Robert Roeven
  • Electronic medical record, library of electronic medical records having polymorphism data, and computer systems and methods for use thereof
    Publication number: 20030104470
    Abstract: The present invention relates to electronic medical records having polymorphisms data, an electronic library of these electronic medical records, and systems and methods for managing genetic information. For example, the present invention provides system and methods for collecting, storing, and retrieving patient-specific genetic information from one or more electronic databases.
    Type: Application
    Filed: August 14, 2001
    Publication date: June 5, 2003
    Applicant: Third Wave Technologies, Inc.
    Inventors: Lance Fors, Rocky Ganske, Amy M. Brower, Witold Ziarno
  • Methods and systems for validating detection assays, developing in-vitro diagnostic DNA or RNA analysis products, and increasing revenue and/or profit margins from in-vitro diagnostic DNA or RNA analysis assays
    Publication number: 20030082544
    Abstract: The present invention provides systems and methods for acquiring and analyzing biological information. For example, the present invention provides systems and methods for the use of genetic information in the generation of assays for detecting the genetic identity of samples, the production of assays, the use of assays for gathering genetic information of individuals and populations, and the storage, analysis, and use of the obtained information.
    Type: Application
    Filed: July 25, 2001
    Publication date: May 1, 2003
    Applicant: Third Wave Technologies, Inc.
    Inventors: Lance Fors, Rocky Ganske
  • Polymorphism analysis by nucleic acid structure probing with structure-bridging oligonucleotides
    Publication number: 20020119454
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Application
    Filed: April 3, 2001
    Publication date: August 29, 2002
    Inventors: Victor I. Lyamichev, Fang Dong, Mary Ann D. Brow, Lance Fors, Bruce P. Neri
  • Target-dependent reactions using structure-bridging oligonucleotides
    Patent number: 6358691
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: March 19, 2002
    Assignee: Third Wave Technologies, Inc.
    Inventors: Bruce Neri, Fang Dong, Victor Lyamichev, Mary Ann D. Brow, Lance Fors
  • Target-dependent reactions using structure-bridging oligonucleotides
    Patent number: 6355437
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: March 12, 2002
    Assignee: Third Wave Technologies, Inc.
    Inventors: Bruce Neri, Fang Dong, Victor Lyamichev, Mary Ann D. Brow, Lance Fors
  • Polymorphism analysis by nucleic acid structure probing
    Patent number: 6214545
    Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: April 10, 2001
    Assignee: Third Wave Technologies, Inc
    Inventors: Fang Dong, Victor I. Lyamichev, James R. Prudent, James E. Dahlberg, Lance Fors