Abstract: Methods and compositions for the treatment of a corneal dystrophy in a subject in need thereof are provided. In one aspect, the method includes the step of obtaining a plurality of stem cells comprising a nucleic acid mutation in a corneal dystrophy target nucleic acid from the subject and manipulating the nucleic acid mutation in one or more stem cells of the plurality of stem cells to correct the nucleic acid mutation, thereby forming one or more manipulated stem cells. The manipulated stem cells are isolated and then transplanted into the subject. In some embodiments, the nucleic acid mutation is manipulated using CRISPR system.

Abstract: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds.

Abstract: An impact tool head is provided, configured to be disposed on an impact tool, the impact tool head including: a rod body and a flange radially protruding from the rod body, the rod body including a working end portion, the flange including an inclined surface facing toward the working end portion and an outermost peripheral edge, a contact position being defined as a position where the inclined surface configured to be contact with at least one projection of the impact tool; wherein as viewed along the axial direction, a distance between the contact position and the outermost peripheral edge is larger than or equal to 0.5 mm.

Abstract: One or more Wireless Access Points (WAPs) are provided for a transportation vehicle. One WAP includes a combined board having a first area with micro-processor components and a second area with antenna elements, the second area located at a periphery of the combined board; a metallic cover placed over the first area; and a non-metallic cover placed over the metallic cover and the second area.

Abstract: A universal joint is provided, including: a seat, including a receiving room extending in an axial direction and at least one through hole in communication with the receiving room; a connecting member, including a ball head rotatably received within the receiving room; and an assembling mechanism, including at least one blocking member and a sleeve member sleeved around the seat, the at least one blocking member being received within the at least one through hole and blockable with the ball head in the axial direction, the sleeve member covering the at least one through hole; wherein the seat has a first hardness, the sleeve member has a second hardness smaller than the first hardness, an outer circumferential wall of the seat is partially embedded within an inner circumferential wall of the sleeve member.

Abstract: A method for enhancing speech control in a subject includes applying a first vibrotactile stimulation and applying a second vibrotactile stimulation to a thyroid area of the subject. The first vibrotactile stimulation has a first vibrating property and the second vibrotactile stimulation has a second vibrating property different than the first vibrating property. Example vibrating properties include vibrating frequency, vibrating frequency range, wave shape, continuousness, frequency phase, and direction of mechanical force. A collar may be configured to position the first vibrational transducer and the second vibrational transducer over a neck of a subject.

Abstract: An impact tool head is provided and configured to be disposed on a front end of an impact tool. The impact tool head includes: a rod body and a flange radially protruding from the rod body. The flange includes an inclined flat surface facing toward the front end and an outermost peripheral edge. A contact position is defined as a position where the inclined flat surface contact with at least one projection of the impact tool. Wherein each of the at least one projection is a ball member, and as viewed in the axial direction, a ratio of a distance between the contact position and the outermost peripheral edge to a radius of the at least one projection is between 0.1 and 0.6.

Abstract: A wind turbine rotor blade assembly which incorporates automatic-aerodynamic control of the blade pitch angle is disclosed. The airfoil of the rotor blade (110) is free to rotate about a strategically located longitudinal blade axis which forms the spar stub (115) and is connected to the hub (120) of a horizontal axis wind turbine. The location of this blade axis is precisely set with respect to the turbine blade's aerodynamic center and center of mass. By further incorporating a reflexed airfoil with positive pitching moment this arrangement aerodynamically induces an automatic and self-regulating alignment of the rotor blade pitch such that the airfoil is always operating at or near optimal angle of attack. Details are disclosed on these strategic relationships which enable the successful operation of the new blade design.

Abstract: A socket wrench is provided, including: a sleeving portion, including a sleeving hole disposed therethrough along a first direction; a connecting arm, extending from the sleeving portion in a direction lateral to the first direction; an operation rod; and a pin member, pinning the connecting arm and the operation rod in a direction non-perpendicular to the first direction so that the operation rod is rotatable about the pin member relative to the sleeving portion.

Abstract: A quick-release tool connecting rod is provided, including: a rod body, a quick-release mechanism and a second sleeve member. The rod body includes an inner space extending in an axial direction and a through hole communicated with the inner space. The quick-release mechanism includes a push rod received within the inner space, a locking member disposed within the through hole and a first sleeve member sleeved to the rod body. The first sleeve member is movable relative to the rod body in the axial direction to drive the push rod to move. The second sleeve member is co-movably sleeved to the first sleeve member, and the first sleeve member is partially embedded within an inner peripheral wall of the second sleeve member. The first sleeve member has a first hardness, and the second sleeve member has a second hardness which is smaller than the first hardness.

Abstract: A valve puller is provided, including: a main body; at least one valve assembly, connected to the main body, configured to be connected with at least one valve head; and a support mechanism, including a connection portion and at least one support body, the connection portion being connected to the main body, the at least one support body being changeably connected with the connection portion, the at least one support body being configured to be abutted against a rim to serve as a fulcrum such that the main body is swingable relative to the rim.

Abstract: A universal joint is provided, including: a seat, including a receiving room extending in an axial direction and at least one through hole in communication with the receiving room; a connecting member, including a ball head rotatably received within the receiving room; and an assembling mechanism, including at least one blocking member and a sleeve member sleeved around the seat, the at least one blocking member being received within the at least one through hole and blockable with the ball head in the axial direction, the sleeve member covering the at least one through hole; wherein the seat has a first hardness, the sleeve member has a second hardness smaller than the first hardness, an outer circumferential wall of the seat is partially embedded within an inner circumferential wall of the sleeve member.

Abstract: A wind turbine rotor blade assembly which incorporates automatic-aerodynamic control of the blade pitch angle is disclosed. The airfoil of the rotor blade (110) is free to rotate about a strategically located longitudinal blade axis which forms the spar stub (115) and is connected to the hub (120) of a horizontal axis wind turbine. The location of this blade axis is precisely set with respect to the turbine blade's aerodynamic center and center of mass. By further incorporating a reflexed airfoil with positive pitching moment this arrangement aerodynamically induces an automatic and self-regulating alignment of the rotor blade pitch such that the airfoil is always operating at or near optimal angle of attack. Details are disclosed on these strategic relationships which enable the successful operation of the new blade design.

Abstract: A socket wrench is provided, including: a sleeving portion, including a sleeving hole disposed therethrough along a first direction; a connecting arm, extending from the sleeving portion in a direction lateral to the first direction; an operation rod; and a pin member, pinning the connecting arm and the operation rod in a direction non-perpendicular to the first direction so that the operation rod is rotatable about the pin member relative to the sleeving portion.

Abstract: A quick-release tool connecting rod is provided, including: a rod body, a quick-release mechanism and a second sleeve member. The rod body includes an inner space extending in an axial direction and a through hole communicated with the inner space. The quick-release mechanism includes a push rod received within the inner space, a locking member disposed within the through hole and a first sleeve member sleeved to the rod body. The first sleeve member is movable relative to the rod body in the axial direction to drive the push rod to move. The second sleeve member is co-movably sleeved to the first sleeve member, and the first sleeve member is partially embedded within an inner peripheral wall of the second sleeve member. The first sleeve member has a first hardness, and the second sleeve member has a second hardness which is smaller than the first hardness.

Abstract: A device includes a first vibrational transducer and a second vibrational transducer. The first vibrational transducer has a first vibrating property. The second vibrotactile stimulator has a second vibrating property different than the first vibrating property. A collar may be configured to position the first vibrational transducer and the second vibrational transducer over a neck of a subject. A method for stimulating swallowing in a subject includes applying a first vibrotactile stimulation and applying a second vibrotactile stimulation to a throat area of the subject. The first vibrotactile stimulation has a first vibrating property and the second vibrotactile stimulation has a second vibrating property different than the first vibrating property. Example vibrating properties include vibrating frequency, vibrating frequency range, wave shape, continuousness, frequency phase, and direction of mechanical force.

Abstract: A brooder system includes a stock tank having opposed sides, a pair of attachment members each having a first portion secured to one of to the opposed sides of the stock tank and a second portion having a vertically-extending passage, a cross member having first and second end portions downwardly extending into the vertically-extending passages of the attachment members so that the cross member extends over the stock tank, and a heat lamp secured to the cross member over the stock tank. The cross member can be slidable within the vertically-extending passages to adjust a height of the heat lamp over the stock tank. The cross member can be flexible and elongate to bend to form an arch over the stock tank.

Abstract: A device includes a first vibrational transducer and a second vibrational transducer. The first vibrational transducer has a first vibrating property. The second vibrotactile stimulator has a second vibrating property different than the first vibrating property. A collar may be configured to position the first vibrational transducer and the second vibrational transducer over a neck of a subject. A method for stimulating swallowing in a subject includes applying a first vibrotactile stimulation and applying a second vibrotactile stimulation to a throat area of the subject. The first vibrotactile stimulation has a first vibrating property and the second vibrotactile stimulation has a second vibrating property different than the first vibrating property. Example vibrating properties include vibrating frequency, vibrating frequency range, wave shape, continuousness, frequency phase, and direction of mechanical force.

Abstract: An impact tool head assembling mechanism is provided, including: an engaging sleeve, disposed on a front end of an impact tool, including a tubular wall and at least one projection, the tubular wall defining an axial direction, the at least one projection being protrudingly and retractably disposed on an inner wall of the tubular wall; an impact tool head, including a rod body and a flange which includes an inclined surface facing toward the front end and an outermost peripheral edge, a contact position being defined as a position where the inclined surface contact with the at least one projection; wherein a reference plane is defined as passing through the outermost peripheral edge and perpendicular to the axial direction, and an included angle between a line from the contact position to the outermost peripheral edge and the reference plane is between 25 and 65 degrees.