Abstract: The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula: (T) where A, B, R1, X1, X2, and W are described herein.

Abstract: The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula: wherein A, X, Y, Z, Q, R1, R2, R3, R4, R5, and n are described herein.

Abstract: A heat exchanger for insertion in a tank which forms part of a vehicle cooler, has a plurality of stacked, flat tubes which consist of a first and a second tube half provided each with one circumferential edge flange, said flanges scalingly engaging with one another and forming a lap joint, and which have at each end a hole to establish communication between the tubes and to form an inlet chamber and an outlet chamber for the fluid to be cooled. The lap joint extends in the direction of the tube thickness in order to form a tube, the inner width of which differs from the outer width by the formulab.sub.i =b.sub.y -4twhereinb.sub.i =the inner width of the tube,b.sub.y =the outer width of the tube, andt=the thickness of the edge flange.

Abstract: Apparatus for a harvesting machine comprising a cutter bar, a reel assembly including a reel, and a rear table comprising a feeding auger and a feeding elevator, with the rear table being pivotable relative to the harvesting machine about a first horizontal axis of rotation. A pair of reel carrying arms are pivotally mounted about an axis of rotation on the rear table, and a movable feeding apron is mounted in front of the rear table. A cutter bar is provided at a leading end of the movable feeding apron, and a pair of levers are hingedly mounted on the rear table about a second horizontal axis of rotation. The levers have front arms and rear arms, with the sides of the feeding apron being connected to the front arms. A first hydraulic arrangement is mounted relative to the machine for pivotally moving the rear table about the first horizontal axis, and a second hydraulic arrangement is provided for supporting the reel assembly and causing pivotal movement of the pair of reel carrying arms.