Patents by Inventor Lars Rose

Lars Rose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF REGORAFENIB AND PD-1/PD-L1(2) INHIBITORS FOR TREATING CANCER
    Publication number: 20200188372
    Abstract: The present invention relates to pharmaceutical compositions and combinations comprising regorafenib or its hydrate, solvate, metabolite or pharmaceutically acceptable salt or a polymorph thereof and a PD-1/PD-L1(2) inhibitor for treating, preventing or managing diseases and conditions including hyperproliferative disorders such as cancer in humans and other mammals.
    Type: Application
    Filed: December 31, 2019
    Publication date: June 18, 2020
    Applicant: BAYER AKTIENGESELLSCHAFT
    Inventors: Sabine HOFF, Lars ROSE, Dieter ZOPF, Fabian KIESSLING, Wiltrud LEDERLE, Dennis DOLESCHEL
  • COMBINATION OF REGORAFENIB AND PD-1/PD-L1(2) INHIBITORS FOR TREATING CANCER
    Publication number: 20200179354
    Abstract: The present invention relates to pharmaceutical compositions and combinations comprising regorafenib or its hydrate, solvate, metabolite or pharmaceutically acceptable salt or a polymorph thereof and a PD-1/PD-L1(2) inhibitor for treating, preventing or managing diseases and conditions including hyperproliferative disorders such as cancer in humans and other mammals.
    Type: Application
    Filed: May 25, 2018
    Publication date: June 11, 2020
    Applicant: BAYER AKTIENGESELLSCHAFT
    Inventors: Sabine HOFF, Lars ROSE, Dieter ZOPF, Fabian KIESSLING, Wiltrud LEDERLE, Dennis DOLESCHEL
  • COMBINATION OF REGORAFENIB AND PD-1/PD-L1(2) INHIBITORS FOR TREATING CANCER
    Publication number: 20200155674
    Abstract: The present invention relates to pharmaceutical compositions and combinations comprising regorafenib or its hydrate, solvate, metabolite or pharmaceutically acceptable salt or a polymorph thereof and a PD-1/PD-L1(2) inhibitor for treating, preventing or managing diseases and conditions including hyperproliferative disorders such as cancer in humans and other mammals.
    Type: Application
    Filed: December 31, 2019
    Publication date: May 21, 2020
    Applicant: BAYER AKTIENGESELLSCHAFT
    Inventors: Sabine HOFF, Lars ROSE, Dieter ZOPF, Fabian KIESSLING, Wiltrud LEDERLE, Dennis DOLESCHEL
  • APPLICATION OF 18-METHYL-15SS,16SS-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONE SYSTEMS IN THE TREATMENT OF MENORRHAGIA, AS WELL AS INTRAUTERINE SYSTEMS CONTAINING 18-METHYL-15SS,16SS-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONE FOR TREATING UTERINE BLEEDING DISORDERS
    Publication number: 20150119372
    Abstract: The present invention describes intrauterine use of 18-methyl-15?,16?-methylene-19-nor-20-spirox-4-en-3-ones of the general formula (1) wherein R6 and R7 are hydrogen or a methylene group, in the treatment of menorrhagia, of uterine haemorrhages in general, and an intrauterine system for said use, comprising a compound of formula 1.
    Type: Application
    Filed: April 19, 2013
    Publication date: April 30, 2015
    Inventors: Norbert Schmees, Lars Röse, Tuula Valo, Katja Prelle, Reinhard Nubbemeyer, Henriikka Korolainen, Harri Jukarainen
  • INTRAUTERINE APPLICATION OF 18-METHYL-15SS,16SS-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONE SYSTEMS, INTRAUTERINE SYSTEMS CONTAINING 18-METHYL-15SS,16SS-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONE, AS WELL AS THE USE THEREOF IN CONTRACEPTION AND GYNAECOLOGICAL THERAPY
    Publication number: 20150065472
    Abstract: The present invention describes intrauterine use of 18-methyl-15?,16?-methylene-19-nor-20-spirox-4-en-3-ones of the general formula (1) in contraception and gynaecological treatment, and an intrauterine system comprising compounds of formula 1.
    Type: Application
    Filed: April 19, 2013
    Publication date: March 5, 2015
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Norbert Schmees, Lars Röse, Tuula Valo, Katja Prelle, Reinhard Nubbemeyer, Henriikka Korolainen, Harri Jukarainen
  • DENSIFIED CERAMIC MATERIALS AND RELATED METHODS
    Publication number: 20100092842
    Abstract: A method for making a densified ceramic layer comprises plasma spraying a layer of the ceramic onto a substrate; spin-coating the plasma-sprayed layer with a sol, and firing the spin-coated ceramic layer. The method may be applied in producing layers of yttria stabilized zirconia (YSZ) having application as electrolyte layers for solid oxide fuel cells or thermal barrier coatings, for example. The firing may be performed at a relatively low temperature such as 650° C. or even below. A method for enhancing electrochemical properties of an interface involving a layer of YSZ or other ceramic comprises spin-coating or otherwise impregnating the layer with a sol and heating the spin-coated layer.
    Type: Application
    Filed: February 8, 2008
    Publication date: April 15, 2010
    Applicants: THE UNIVERSITY OF BRITISH COLUMBIA, NORTHWEST METTECH CORPORATION
    Inventors: Lars Rose, Olivera Kesler, Alan Burgess, Zhaolin Tang