Abstract: The present disclosure relates to compositions, for treating interleukin 5 (IL-5) mediated diseases, and related methods.

Abstract: A protocol is implemented for remotely preparing quantum states, with application to blind and verifiable delegated quantum computation. A remote-state preparation protocol relies on the use of cryptographic primitives known as Noisy Trapdoor Claw-Free (NTCF) functions. The NTCF functions are based on conjectured post-quantum secure problems. The NTCF functions are evaluated in superposition on a Noisy-Intermediate Size Quantum (NISQ) device. Thereby, the potential of NISQ devices for cryptographic applications is assessed.

Abstract: An imaging-based biomarker that indicates a neurological state of a subject is generated from magnetic resonance imaging data acquired from the subject while the subject was sleeping, or during both a sleep state and wake state. These magnetic resonance imaging data are acquired in such a way so that they simultaneously enable measurement of cerebrospinal fluid (“CSF”) flow and blood-oxygenation-level dependent (“BOLD”) signals. The imaging-based biomarker can be generated based on a correlation between CSF signals and BOLD signals extracted from these magnetic resonance imaging data. Using electroencephalography (“EEG”) data, CSF flow dynamics can also be estimated based on a physiological model in which coherent neural activity is modeled as entraining oscillations in blood volume and CSF.

Abstract: Methods and devices including amorphous magnetic microwires are provided for biomedical energy transfer for diagnosis or therapy, to promote cellular growth, or to deliver pharmaceutical agents. Applications of the technology include in sensors, actuators, and therapeutic coatings, and for increasing the amount, directionality, or length of nerve growth. The technology also can be utilized for nerve regeneration, hyperthermic treatment of tumors, vascular theranostics, probing a nerve, stimulating a nerve, sensing a biological condition, catheterization, and micro-actuation.

Abstract: A magnetocaloric effect heterostructure having a core layer of a magnetostructural material with a giant magnetocaloric effect having a magnetic transition temperature equal to or greater than 150 K, and a constricting material layer coated on at least one surface of the magnetocaloric material core layer. The constricting material layer may enhance the magnetocaloric effect by restriction of volume changes of the core layer during application of a magnetic field to the heterostructure. A magnetocaloric effect heterostructure powder comprising a plurality of core particles of a magnetostructural material with a giant magnetocaloric effect having a magnetic transition temperature equal to or greater than 150 K, wherein each of the core particles is encapsulated within a coating of a constricting material is also disclosed.

Abstract: A method of providing energy efficiency changes to a plurality of energy consumers. The method includes calculating the energy efficiency changes for the consumers based on energy consumption histories and weather data, wherein the energy efficiency changes are calculated using individual data for each of the consumers. The method also includes reporting the energy efficiency changes to each of the consumers.

Abstract: A method of providing one of a good or a service to at least one entity at one of a payment, rate, or price that is capped at a pre-determined amount. The method includes producing an offer for the entity, wherein the offer represents one of a capped maximum payment, a capped maximum rate, or a capped maximum price amount and receiving an insurance premium. The method also includes providing the good or service to the entity at one of a payment, rate, or price that may fluctuate, wherein the payment, rate, or price cannot exceed the capped maximum payment, capped maximum rate, or capped maximum price amount and paying an insurance proceed when an actual price of the good or service exceeds the capped maximum payment, capped maximum rate, or capped maximum price amount.

Abstract: A cooling system and related method of defrosting a refrigeration unit or a freezer unit involves the steps of (a) monitoring a compressor running time, (b) monitoring an evaporator coil temperature, (c) monitoring a first time period since a last cooled compartment door open alarm of the unit, (d) monitoring a second time period since a last defrost operation, (e) monitoring a third time period during which the cooled compartment door is closed, and (f) controlling initiation of a defrost operation as a function of the monitored compressor running time, the monitored evaporator coil temperature, the monitored first time period, the monitored second time period, and the monitored third time period. Various sets of conditions may be established for triggering initiation of the defrost operation. The system may also detect refrigerant leaks and a clogged condenser as a function of compressor running time and compressor discharge line temperature.

Abstract: A cooling system and related method of defrosting a refrigeration unit or a freezer unit involves the steps of (a) monitoring a compressor running time, (b) monitoring an evaporator coil temperature, (c) monitoring a first time period since a last cooled compartment door open alarm of the unit, (d) monitoring a second time period since a last defrost operation, (e) monitoring a third time period during which the cooled compartment door is closed, and (f) controlling initiation of a defrost operation as a function of the monitored compressor running time, the monitored evaporator coil temperature, the monitored first time period, the monitored second time period, and the monitored third time period. Various sets of conditions may be established for triggering initiation of the defrost operation. The system may also detect refrigerant leaks and a clogged condenser as a function of compressor running time and compressor discharge line temperature.

Abstract: A cooling system and related method of defrosting a refrigeration unit or a freezer unit involves the steps of (a) monitoring a compressor running time, (b) monitoring an evaporator coil temperature, (c) monitoring a first time period since a last cooled compartment door open alarm of the unit, (d) monitoring a second time period since a last defrost operation, (e) monitoring a third time period during which the cooled compartment door is closed, and (f) controlling initiation of a defrost operation as a function of the monitored compressor running time, the monitored evaporator coil temperature, the monitored first time period, the monitored second time period, and the monitored third time period. Various sets of conditions may be established for triggering initiation of the defrost operation. The system may also detect refrigerant leaks and a clogged condenser as a function of compressor running time and compressor discharge line temperature.