Patents by Inventor LAURA SERWER

LAURA SERWER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymeric forms of H-NOX proteins
    Patent number: 11987614
    Abstract: The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
    Type: Grant
    Filed: August 9, 2021
    Date of Patent: May 21, 2024
    Assignee: OMNIOX, INC.
    Inventors: Gregory Kapp, Laura Serwer, Natacha Le Moan, Stephen P. L. Cary
  • METHODS AND COMPOSITIONS FOR TREATING LIPOPROTEIN-RELATED DISEASES
    Publication number: 20230293646
    Abstract: The present disclosure relates to methods, compositions and kits for modulating the expression of LPA gene and for treating lipoprotein-related diseases, for example cardiovascular diseases, in a subject by gene editing.
    Type: Application
    Filed: March 20, 2023
    Publication date: September 21, 2023
    Inventors: Sanjay D'Souza, Laura Serwer, Jonathan Terrett, John Kulman
  • METHODS AND COMPOSITIONS FOR TREATING ANGIOPOIETIN-LIKE 3 (ANGPTL3) RELATED CONDITIONS
    Publication number: 20230279376
    Abstract: The present disclosure relates to methods, compositions and kits for treating conditions that are related with angiopoietin-like 3 (ANGPTL3) by gene editing.
    Type: Application
    Filed: February 28, 2023
    Publication date: September 7, 2023
    Inventors: Yi-Shan Chen, Sandeep Soni, Laura Serwer, Jonathan Terrett, John Kulman
  • POLYMERIC FORMS OF H-NOX PROTEINS
    Publication number: 20220048977
    Abstract: The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
    Type: Application
    Filed: August 9, 2021
    Publication date: February 17, 2022
    Inventors: Gregory Kapp, Laura Serwer, Natacha Le Moan, Stephen P. L. Cary
  • Polymeric forms of H-NOX proteins
    Patent number: 11117952
    Abstract: The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: September 14, 2021
    Assignee: OMNIOX, INC.
    Inventors: Gregory Kapp, Laura Serwer, Natacha Le Moan, Stephen P. L. Cary
  • POLYMERIC FORMS OF H-NOX PROTEINS
    Publication number: 20210002351
    Abstract: The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
    Type: Application
    Filed: July 17, 2020
    Publication date: January 7, 2021
    Applicant: Omniox, Inc.
    Inventors: Gregory Kapp, Laura Serwer, Natacha Le Moan, Stephen P. L. Cary
  • Polymeric forms of H-NOX proteins
    Patent number: 10766947
    Abstract: The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: September 8, 2020
    Assignee: Omniox, Inc.
    Inventors: Gregory Kapp, Laura Serwer, Natacha Le Moan, Stephen P. L. Cary
  • POLYMERIC FORMS OF H-NOX PROTEINS
    Publication number: 20200017574
    Abstract: The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
    Type: Application
    Filed: June 24, 2019
    Publication date: January 16, 2020
    Applicant: Omniox, Inc.
    Inventors: Gregory Kapp, Laura Serwer, Natacha Le Moan, Stephen P. L. Cary
  • Polymeric forms of H-NOX proteins
    Patent number: 10385116
    Abstract: The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: August 20, 2019
    Assignee: Omniox, Inc.
    Inventors: Gregory Kapp, Laura Serwer, Natacha Le Moan, Stephen P. L. Cary
  • POLYMERIC FORMS OF H-NOX PROTEINS
    Publication number: 20160185839
    Abstract: The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
    Type: Application
    Filed: January 7, 2013
    Publication date: June 30, 2016
    Applicant: Omniox, Inc.
    Inventors: Gregory KAPP, Laura SERWER, Natacha LE MOAN, Stephen P.L. CARY
  • BIOMARKERS FOR H-NOX DELIVERY OF OXYGEN
    Publication number: 20150273024
    Abstract: The invention provides methods to monitor tumor oxygenation by H-NOX proteins. H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. For example, the invention provides methods to monitor brain tumor oxygenation by H-NOX proteins for enhanced treatment of brain cancers.
    Type: Application
    Filed: October 31, 2014
    Publication date: October 1, 2015
    Inventors: STEPHEN P. L. CARY, ANA KRTOLICA, NATACHA LE MOAN, LAURA SERWER, JENNIFER A. GETZ