Abstract: Disclosed is an intraocular lens (IOL) including an anterior surface, a posterior surface and an optical axis. At least one of the anterior or posterior surfaces has a diffractive profile formed thereon. The diffractive profile has diffractive focal points for far vision, intermediate vision, and near vision. The diffractive profile corresponds to a superposition of a first partial diffractive profile and a second partial diffractive profile, the first partial diffractive profile has a focal point of order +n that coincides with the diffractive focal point for intermediate vision or with the diffractive focal point for near vision, the second partial diffractive profile has a focal point of order +n that coincides with the diffractive focal point for far vision and a focal point of higher order than +n that coincides with the diffractive focal point for near vision.

Abstract: Disclosed is an intraocular lens (IOL) including an anterior surface, a posterior surface and an optical axis. At least one of the anterior or posterior surfaces has a diffractive profile formed thereon. The diffractive profile has diffractive focal points for far vision, intermediate vision, and near vision. The diffractive profile corresponds to a superposition of a first partial diffractive profile and a second partial diffractive profile, the first partial diffractive profile has a focal point of order +n that coincides with the diffractive focal point for intermediate vision or with the diffractive focal point for near vision, the second partial diffractive profile has a focal point of order +n that coincides with the diffractive focal point for far vision and a focal point of higher order than +n that coincides with the diffractive focal point for near vision.

Abstract: The present invention relates to compositions and methods for enhancing nucleic acid transfer into cells and especially for enhancing nucleic acid transfer into cells for which conventional non-viral transfection methods and compositions are inefficient. More specifically, the present invention is concerned with nucleic acid delivery compositions and methods comprising cationic polymers. The present invention particularly relates to compositions and methods for transfecting cells using a nucleic acid-cationic polymer-lipid mixture. The compositions and methods of the present invention display significantly improved transfection efficiency over other non-viral delivery formulations and methods.