Patents by Inventor Lauren Gutgesell

Lauren Gutgesell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS, COMPOSITIONS, AND SYSTEMS FOR SPATIAL ANALYSIS OF ANALYTES IN A BIOLOGICAL SAMPLE
    Publication number: 20240141327
    Abstract: Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.
    Type: Application
    Filed: January 10, 2024
    Publication date: May 2, 2024
    Inventors: Hanyoup Kim, David Sukovich, Layla Katiraee, Augusto Manuel Tentori, Lauren Gutgesell, Janine Hensel, Seayar Mohabbat
  • Methods, compositions, and systems for spatial analysis of analytes in a biological sample
    Patent number: 11873482
    Abstract: Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.
    Type: Grant
    Filed: April 27, 2023
    Date of Patent: January 16, 2024
    Assignee: 10x Genomics, Inc.
    Inventors: Hanyoup Kim, David Sukovich, Layla Katiraee, Augusto Manuel Tentori, Lauren Gutgesell, Janine Hensel, Seayar Mohabbat
  • SUBSTITUTED BENZOTHIOPHENE ANALOGS AS SELECTIVE ESTROGEN RECEPTOR DEGRADERS
    Publication number: 20230381137
    Abstract: In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Application
    Filed: August 3, 2023
    Publication date: November 30, 2023
    Inventors: Gregory R THATCHER, Rui XIONG, Jiong ZHAO, Yunlong LU, Lauren GUTGESELL, Carlo Ivan ROSALES, Yangfeng LI
  • METHODS, COMPOSITIONS, AND SYSTEMS FOR SPATIAL ANALYSIS OF ANALYTES IN A BIOLOGICAL SAMPLE
    Publication number: 20230332138
    Abstract: Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.
    Type: Application
    Filed: April 27, 2023
    Publication date: October 19, 2023
    Inventors: Hanyoup Kim, David Sukovich, Layla Katiraee, Augusto Manuel Tentori, Lauren Gutgesell, Janine Hensel, Seayar Mohabbat
  • Substituted benzothiophene analogs as selective estrogen receptor degraders
    Patent number: 11759450
    Abstract: In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: September 19, 2023
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Gregory R. Thatcher, Rui Xiong, Jiong Zhao, Yunlong Lu, Lauren Gutgesell, Carlo Ivan Rosales, Yangfeng Li
  • Methods, compositions, and systems for spatial analysis of analytes in a biological sample
    Patent number: 11680260
    Abstract: Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: June 20, 2023
    Assignee: 10x Genomics, Inc.
    Inventors: Hanyoup Kim, David Sukovich, Layla Katiraee, Augusto Manuel Tentori, Lauren Gutgesell, Janine Hensel, Seayar Mohabbat
  • METHODS, COMPOSITIONS, AND SYSTEMS FOR SPATIAL ANALYSIS OF ANALYTES IN A BIOLOGICAL SAMPLE
    Publication number: 20230113230
    Abstract: Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.
    Type: Application
    Filed: October 28, 2022
    Publication date: April 13, 2023
    Inventors: Hanyoup Kim, David Sukovich, Layla Katiraee, Augusto Manuel Tentori, Lauren Gutgesell, Janine Hensel, Seayar Mohabbat
  • SUBSTITUTED BENZOTHIOPHENE ANALOGS AS SELECTIVE ESTROGEN RECEPTOR DEGRADERS
    Publication number: 20220062230
    Abstract: In one aspect, the disclosure relates to relates to substituted benzothiophene analogs which are useful as selective degraders of estrogen receptor, methods of making same, pharmaceutical compositions comprising same, and methods of treating one or more clinical conditions associated with estrogen receptor, such as a cancer, including breast cancer, or osteoporosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Application
    Filed: February 6, 2019
    Publication date: March 3, 2022
    Inventors: Gregory R. Thatcher, Rui Xiong, Jiong Zhao, Yunlong Lu, Lauren Gutgesell, Carlo Ivan Rosales, Yanfeng Li