Abstract: An acellular, anion-depleted platelet-derived peptide-rich composition comprising proteins, polypeptides and peptides <10 kDa in size, wherein the composition has anti-microbial and/or anti-inflammatory activity is disclosed. The composition can be substantially free of non-active and immunogenic factors. The composition can have a platelet-to-bacteria ratio ?1000:1. The composition can comprise plasma at a range of ?10% to ?50% plasma, optionally about 10% plasma. Methods of using the composition are also disclosed.

Abstract: Non-human animal compression therapy devices and methods. In some embodiments, the compression therapy devices includes one or more sleeves, each of the one or more sleeves being configured to fit a limb of a non-human animal, and each of the one or more sleeves comprising one or more inflatable chambers; and a controllable air source operably connected with the one or more inflatable chambers and configured to controllably inflate and deflate the one or more inflatable chambers. In some embodiments, at least one cycle of inflating and deflating of the one or more chambers starts by inflating the most distal chamber. In some embodiments, the compression therapy is given to eliminate or ease suffering from a disease or disorder or a sporting or work-related injury.

Abstract: An acellular, anion-depleted platelet-derived peptide-rich composition comprising proteins, polypeptides and peptides <10 kDa in size, wherein the composition has anti-microbial and/or anti-inflammatory activity is disclosed. The composition can be substantially free of non-active and immunogenic factors. The composition can have a platelet-to-bacteria ratio ?1000:1. The composition can comprise plasma at a range of ?10% to ?50% plasma, optionally about 10% plasma. Methods of using the composition are also disclosed.