Abstract: The present disclosure relates to a medical device and methods of using the same. In embodiments, the medical device may be a buttress formed of nucleophilic buttress components and electrophilic buttress components which react to both form the buttress and provide the buttress with self-sealing capabilities after a staple or some other fixation device is placed therethrough, thereby enhancing its hemostatic properties. In other embodiments, the medical device is a hernia patch formed of a fibrous substrate, nucleophilic precursor components and electrophilic precursor components.

Abstract: The present disclosure relates to compositions suitable for use as medical devices and/or coatings thereon. In embodiments, the compositions may be used to adhere and/or seal tissue. In other embodiments, coatings may be used to at least temporarily affix a medical device to tissue. The coatings may affix a medical device to tissue without the need for additional fixation devices or, in embodiments, may be used with other fixation devices to affix a medical device to tissue.

Abstract: The present disclosure relates to a medical device and methods of using the same. In embodiments, the medical device may be a buttress formed of nucleophilic buttress components and electrophilic buttress components which react to both form the buttress and provide the buttress with self-sealing capabilities after a staple or some other fixation device is placed therethrough, thereby enhancing its hemostatic properties. In other embodiments, the medical device is a hernia patch formed of a fibrous substrate, nucleophilic precursor components and electrophilic precursor components.