Abstract: A portable cooler for use in transporting medicines or the like which must be kept at lower than room temperature includes an insulative housing containing a coolant compartment and a medicine compartment, each having its own lid, and heat sinks in the compartments thermally connected by a heat tube. Water ice, dry ice, or a chilled gel may be utilized as the coolant. The whole assembly is enclosed in a carrying case about the size and weight of a carrying case for binoculars or a camera.