Abstract: The present invention relates to a powder composition I comprising nanoparticles A blended with a polyolefinic powder II, said polyolefinic powder II containing particles B embedded in a polyolefinic matrix C, nanoparticles A being metal or metal oxide nanoparticles and particles B being metal, nitride, carbide or metal oxide micro or nanoparticles, said powder composition I containing at least 90 wt % of polyolefinic matrix C relative to the total weight of the powder composition I. The invention further relates to the preparation of said powder composition I and its use in an additive process for the preparation of a 3D printed article.

Abstract: This invention relates to pyrimidine prodrug derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.

Abstract: Crystalline forms of seletalisib, designated as Form B and Form F and characterized herein, being selective inhibitors of PI3 kinase enzymes, in particular of the human PBK? isoform, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

Abstract: This invention relates to pyrimidine prodrug derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.

Abstract: The invention relates to a part of revolution (60) intended to be rotated, comprising a hub (62) intended to be tightly adjusted on a rotary shaft (24), and a body (14) extending radially outwards from an axial end of the hub. In order to increase the critical speed up to which the tightening can be retained, the hub (62) comprises three relatively thick annular regions (68, 66, 70) separated from one another by two relatively thin annular regions (64a, 64b), in such a way that when the part of revolution is subject to a centrifugal force (F), the two relatively thin annular regions (64a, 64b) form privileged deformation zones acting as a double pivot. Such a part can advantageously be used as a piston for balancing in a turbine test bench or in a turbomachine.

Abstract: Crystalline forms of seletalisib, designated as Form B and Form F and characterized herein, being selective inhibitors of PI3 kinase enzymes, in particular of the human PBK? isoform, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

Abstract: This invention relates to pyrimidine prodrug derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.

Abstract: An omnidirectional sensor array system, for example a panoptic camera, comprising a plurality of sensors arranged on a support of predetermined shape to acquire data, wherein said sensors are directional and wherein each sensor is attached to a processing node which comprises integrated electronics that carries out at least a portion of the signal processing algorithms locally in order to reduce the computational load of a central hardware unit.

Abstract: The invention relates to a part of revolution (60) intended to be rotated, comprising a hub (62) intended to be tightly adjusted on a rotary shaft (24), and a body (14) extending radially outwards from an axial end of the hub. In order to increase the critical speed up to which the tightening can be retained, the hub (62) comprises three relatively thick annular regions (68, 66, 70) separated from one another by two relatively thin annular regions (64a, 64b), in such a way that when the part of revolution is subject to a centrifugal force (F), the two relatively thin annular regions (64a, 64b) form privileged deformation zones acting as a double pivot. Such a part can advantageously be used as a piston for balancing in a turbine test bench or in a turbomachine.

Abstract: The invention relates to a trunnion (23) for a high-pressure turbine (11), to be arranged between a shaft of a low-pressure turbine (9) and an inner surface (34) of a seal mounting (26) of the low-pressure turbine (8), the trunnion (23) being characterized in that it includes a drop-launching extension (32) arranged such as to extend opposite a flared portion (33) of the inner surface (34) of the seal mounting (26), such that when the trunnion (23) is rotated about the shaft of the low-pressure turbine (9), oil (H2), which tends to penetrate between the trunnion (23) and the seal mounting (26), is thrown by centrifugal effect from the drop-launching extension (32) toward the flared portion (33) of the inner surface (34) of the seal mounting (26).

Abstract: An omnidirectional sensor array system, for example a panoptic camera, comprising a plurality of sensors arranged on a support of predetermined shape to acquire data, wherein said sensors are directional and wherein each sensor is attached to a processing node which comprises integrated electronics that carries out at least a portion of the signal processing algorithms locally in order to reduce the computational load of a central hardware unit.

Abstract: An omnidirectional sensor array system, for example a panoptic camera, comprising a plurality of sensors arranged on a support of predetermined shape to acquire data, wherein said sensors are directional and wherein each sensor is attached to a processing node which comprises integrated electronics that carries out at least a portion of the signal processing algorithms locally in order to reduce the computational load of a central hardware unit.

Abstract: Methods and systems are provided for an electromagnetic coil assembly for a surgical navigation tracking system which may be used during image-guided surgery. A medical instrument assembly for an electromagnetic surgical navigation system, may comprise a tracking sensor interface included within a handle of a medical instrument, the interface having a first mating surface. Further, the assembly may include a tracking sensor including a second mating surface and one or more electromagnetic coils, where the tracking sensor is removably coupled to the tracking sensor interface of the medical instrument via an attachment device included on one or more of the first mating surface and second mating surface.

Abstract: Methods and systems are provided for a patient reference assembly for an electromagnetic tracking system for use in image-guided surgery. In one embodiment, a patient reference assembly for an electromagnetic surgical navigation system includes a mounting platform including a first mating interface and an attachment interface shaped to couple to a patient.

Abstract: A hybrid tracking system utilizing at least one combined light emitting diode (LED) and magnetoresistance sensor. The hybrid tracking system includes optical tracking technology and electromagnetic (EM) tracking technology with at least one combined LED and magnetoresistance reference sensor attached to a fixed object, at least one combined LED and magnetoresistance sensor attached to an object being tracked, and a processor coupled to the at least one combined LED and magnetoresistance reference sensor and the at least one combined LED and magnetoresistance sensor for processing signals from the at least one combined LED and magnetoresistance reference sensor and the at least one combined LED and magnetoresistance sensor. The combined LED and magnetoresistance sensor includes at least one magnetoresistance sensor and at least one LED that are integrated into a single package.

Abstract: The novel biomaterial fillers containing cross-linked sodium alginate and the method for manufacturing same are used in the medical field and are intended for filling tissue lesions having a layered structure of varying compositions, such as cartilage, skin or the epithelium. These novel biomaterials have the special feature of being multiphasic, composite and functionalized, for medical use and, in particular, for treating tissue lesions having a layered structure of varying compositions. The biomaterials are particularly suitable for treating focal lesions of the articular cartilage.

Abstract: An omnidirectional sensor array system, for example a panoptic camera, comprising a plurality of sensors arranged on a support of predetermined shape to acquire data, wherein said sensors are directional and wherein each sensor is attached to a processing node which comprises integrated electronics that carries out at least a portion of the signal processing algorithms locally in order to reduce the computational load of a central hardware unit.

Abstract: A hybrid tracking system utilizing at least one combined light emitting diode (LED) and magnetoresistance sensor. The hybrid tracking system includes optical tracking technology and electromagnetic (EM) tracking technology with at least one combined LED and magnetoresistance reference sensor attached to a fixed object, at least one combined LED and magnetoresistance sensor attached to an object being tracked, and a processor coupled to the at least one combined LED and magnetoresistance reference sensor and the at least one combined LED and magnetoresistance sensor for processing signals from the at least one combined LED and magnetoresistance reference sensor and the at least one combined LED and magnetoresistance sensor. The combined LED and magnetoresistance sensor includes at least one magnetoresistance sensor and at least one LED that are integrated into a single package.