Patents by Inventor Laurent Martarello

Laurent Martarello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS
    Publication number: 20220290140
    Abstract: Featured are trans-cyclooctene and tetrazine compounds. Also provided are methods for evaluating the biodistribution and/or concentration of a biomolecule in a subject.
    Type: Application
    Filed: August 19, 2020
    Publication date: September 15, 2022
    Inventors: Brendon Ellery COOK, Maciej Adam KALISZCZAK, Laurent MARTARELLO, Nathan Edward GENUNG, Sivaraman DANDAPANI, Eric Edward SWAYZE, William John DRURY, III, Chrissa Ann DWYER
  • RADIOLABELED COMPOUNDS
    Publication number: 20160031878
    Abstract: The present invention relates to radiolabeled compounds of formula I wherein R1, R2, R3 and R4 are as defined herein.
    Type: Application
    Filed: July 30, 2015
    Publication date: February 4, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Edilio BORRONI, Alexander FLOHR, Luca GOBBI, Thomas HARTUNG, Raphael HOAREAU, Michael HONER, Laurent MARTARELLO
  • Radicicol Derivatives Useful for Position Emission Tomography
    Publication number: 20080311038
    Abstract: The present invention relates to novel radicicol derivatives of the formula I, in which R is R?, (CH2)nCOOR? or (CH2)nCONHR?, wherein R? is 11CH3, [3H]3C, [3H]2HC, [3H]H2C or (CH2)nHal, wherein Hal is 123I, 125I, 131I, I, 75Br, 76Br, 77Br, 82Br, Br, 18F or F, or R? is (CH2)n-1[3H]HCHal or (CH2)n-1[3H]2CHal, wherein Hal is I, Br or F, and n is, each independently, 1, 2, 3 or 4, in free form or in salt form, to their preparation, to their use as radiotracers/markers and to compositions containing them.
    Type: Application
    Filed: January 2, 2007
    Publication date: December 18, 2008
    Inventors: Yves Auberson, Mats Bergstroem, Emmanuelle Briard, Patrick Chene, Laurent Martarello, Joseph Schoepfer
  • 4-haloethenylphenyl tropane:serotonin transporter imaging agents
    Patent number: 6843979
    Abstract: A series of compounds in the 4-fluoroalkyl-3-halophenyl nortropanes and 4-haloethenylphenyl tropane families are described as diagnostic and therapeutic agents for diseases associated with serotonin transporter dysfunction. These compounds bind to serotonin transporter protein with high affinity and selectivity. The invention provides methods of synthesis which incorporate radioisotopic halogens at a last step which permit high radiochemical yield and maximum usable product life. The radiolabeled compounds of the invention are useful as imaging agents for visualizing the location and density of serotonin transporter by PET and SPECT imaging.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: January 18, 2005
    Assignee: Emory University
    Inventors: Mark M. Goodman, Laurent Martarello
  • 4-Haloethenyphenyl tropane:serotonin transporter imaging agents
    Publication number: 20020099184
    Abstract: A series of compounds in the 4-fluoroalkyl-3-halophenyl nortropanes and 4-haloethenylphenyl tropane families are described as diagnostic and therapeutic agents for diseases associated with serotonin transporter dysfunction. These compounds bind to serotonin transporter protein with high affinity and selectivity. The invention provides methods of synthesis which incorporate radioisotopic halogens at a last step which permit high radiochemical yield and maximum usable product life. The radiolabeled compounds of the invention are useful as imaging agents for visualizing the location and density of serotonin transporter by PET and SPECT imaging.
    Type: Application
    Filed: October 9, 2001
    Publication date: July 25, 2002
    Inventors: Mark M. Goodman, Laurent Martarello