Patents by Inventor LaVerne D. Boeck

LaVerne D. Boeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insecticide and miticide compositions containing A83543 compounds
    Patent number: 5571901
    Abstract: Fermentation product A83543, comprising major components A83543A and A83543D and minor components A83543B, A83543C, A83543E, A83543F, A83543G, A83543H and A83543J, is produced by a newly described species, Saccharopolyspora spinosa. The A83543 components and their acid-addition salts (A83543 compounds) are useful as insecticides, particularly against Lepidoptera and Diptera species. Insecticidal, miticidal or ectoparasiticidal combinations, compositions and methods are provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 5, 1996
    Assignee: DowElanco
    Inventors: LaVerne D. Boeck, Hang Chio, Tom E. Eaton, Otis W. Godfrey, Jr., Karl H. Michel, Walter M. Nakatsukasa, Raymond C. Yao
  • Insecticide and miticide A83543 compounds and their method of production by fermentation
    Patent number: 5496931
    Abstract: Fermentation product A83543, comprising major components A83543A and A83543D and minor components A83543B, A83543C, A83543E, A983543F, A83543G, A83543H and A83543J, is produced by a newly described species, Saccharopolyspora spinosa. The A83543 components and their acid-addition salts (A83543 compounds) are useful as insecticides, particularly against Lepidoptera and Diptera species. Insecticidal, miticidal or ecto-parasiticidal combinations, compositions and methods are provided.
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: March 5, 1996
    Assignee: DowElanco
    Inventors: LaVerne D. Boeck, Hang Chio, Tom E. Eaton, Otis W. Godfrey, Jr., Karl H. Michel, Walter M. Nakatsukasa, Raymond C. Yao
  • Process for producing A83543 compounds
    Patent number: 5362634
    Abstract: Fermentation product A83543, comprising major components A83543A and A83543D and minor components A83543B, A83543C, A83543E, A983543F, A83543G, A83543H and A83543J, is produced by a newly described species, Saccharopolyspora spinosa. The A83543 components and their acid-addition salts (A83543 compounds) are useful as insecticides, particularly against Lepidoptera and Diptera species. Insecticidal, miticidal or ecto-parasiticidal combinations, compositions and methods are provided.
    Type: Grant
    Filed: October 10, 1991
    Date of Patent: November 8, 1994
    Assignee: DowElanco
    Inventors: LaVerne D. Boeck, Hang Chio, Tom E. Eaton, Otis W. Godfrey, Jr., Karl H. Michel, Walter M. Nakatsukasa, Raymond C. Yao
  • Process for producing the A10255 complex and corresponding microorganism
    Patent number: 5286631
    Abstract: Newly-discovered antibiotic A10255 factors B, C, E, and F are produced by submerged aerobic fermentation of previously-unknown Streptomyces gardneri strain NRRL 15922, or an A10255-producing variant, mutant or recombinant thereof. The antibiotics are active against a wide variety of pathogenic bacteria, and also enhance feed-utilization efficiency in chickens, weanling pigs and cattle.
    Type: Grant
    Filed: February 28, 1991
    Date of Patent: February 15, 1994
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, Otis W. Godfrey, Jr., Karl H. Michel
  • Method of producing a polyether antibiotic from actinomadura fibrosa sp. nov. NRRL 18348 and actinomadura sp. NRRL 18880
    Patent number: 5278053
    Abstract: Improved processes for producing a polyether antibiotic compound represented by A82810 comprising: (1) cultivating Actinomadura fibrosa sp. nov. NRRL 18348 or Actinomadura sp. NRRL 18880, (2) feeding acid hydrolyzed casein at a rate from about 2.50-7.50 gm/L/day, (3) feeding glucose at a rate from about 2.50-7.50 gm/L/day, and (4) feeding propionate at a rate from about 0.50-1.5 gm/L/day to the appropriate culture medium during fermentation, are provided.
    Type: Grant
    Filed: September 16, 1991
    Date of Patent: January 11, 1994
    Assignee: Eli Lilly and Company
    Inventor: LaVerne D. Boeck
  • A54145 antibiotics and process for their production
    Patent number: 4994270
    Abstract: New peptide antibiotic A54145, individual A54145 components A, A.sub.1, B, B.sub.1, C, D, E and F and their pharmaceutically acceptable salts, are useful antibacterial agents which also improve growth performance in animals, especially poultry. Biologically pure cultures of the A54145-producing Streptomyces fradiae cultures NRRL 18158, NRRL 18159 and NRRL 18160 cultures and methods of making antibiotic A54145 using those cultures are also provided.
    Type: Grant
    Filed: April 11, 1988
    Date of Patent: February 19, 1991
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, David S. Fukuda, Jon S. Mynderse, Marvin M. Hoehn, Ralph E. Kastner, Harold R. Papiska
  • Processes for preparing A54145 compounds
    Patent number: 4977083
    Abstract: Improved processes for preparing A54145 components and cyclic peptide derivatives (A54145 compounds) comprising: (1) feeding alkanoic or alkenoic acids or alcohols, or esters or salts thereof, (2) feeding glucose at a rate from about 6-9 g/L/day, or (3) feeding enzymatic soy digest at a rate from about 2-4 g/L/day to an A54145-producing culture during its fermentation and recovering the A54145 compound, are provided.
    Type: Grant
    Filed: April 11, 1988
    Date of Patent: December 11, 1990
    Assignee: Eli Lilly and Company
    Inventor: LaVerne D. Boeck
  • A-51568B antibiotic
    Patent number: 4717714
    Abstract: The novel glycopeptide antibiotic A-51568B is produced by submerged, aerobic fermentation of Nocardia orientalis NRRL 15232. A-51568B demonstrates antibiotic activity against gram-positive bacteria.
    Type: Grant
    Filed: September 12, 1986
    Date of Patent: January 5, 1988
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, Gary G. Marconi, Marvin M. Hoehn
  • Process for producing antibiotic A80190
    Patent number: 4683204
    Abstract: Improved fermentation process for producing the polyether antibiotic A80190 which comprises cultivating a new strain of Actinomodura Oligospora, NRRL 15878, and the biologically purified culture of this microorganism are provided.
    Type: Grant
    Filed: October 9, 1984
    Date of Patent: July 28, 1987
    Assignee: Eli Lilly and Company
    Inventor: LaVerne D. Boeck
  • Glycopeptide antibiotic CUC/CSV and process for its production
    Patent number: 4663282
    Abstract: New glycopeptide antibiotic CUC/CSV which has the formula: ##STR1## wherein R is L-ristosaminyl;R.sub.1 is the disaccharide mannosyl-glucosyl; andR.sub.2 and R.sub.3 are mannosyl, and its salts, particularly the pharmaceutically acceptable salts, are useful new antibiotics are active against gram-positive bacteria and increase feed-efficiency utilization and enhance milk production in ruminants.
    Type: Grant
    Filed: May 2, 1985
    Date of Patent: May 5, 1987
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, Gladys M. Clem, Charles L. Hershberger, Marie T. Anderson, Karl H. Michel
  • Glycopeptide bioconversion products
    Patent number: 4563442
    Abstract: New glycopeptide antibiotics of the formula: ##STR1## wherein W is the remaining portion of a glycopeptide antibiotic selected from actaplanin factors B.sub.1, B.sub.2, B.sub.3, C.sub.1, C.sub.2, C.sub.3, D.sub.1, D.sub.2, E.sub.1, G, K, L, M, N, O and actaplanin .psi.aglycone, and salts thereof, particularly the pharmaceutically acceptable salts, are useful new antibiotics are active against gram-positive bacteria and increase feed-efficiency utilization and enhance milk production in ruminants.
    Type: Grant
    Filed: September 24, 1984
    Date of Patent: January 7, 1986
    Assignee: Eli Lilly and Company
    Inventors: Gladys M. Clem, LaVerne D. Boeck, Marie T. Anderson, Karl H. Michel
  • Antibiotic A39079 factor S-1
    Patent number: 4560509
    Abstract: A new antibiotic of the rifamycin class, A39079 factor S-1, which has the structure ##STR1## is an effective broad-spectrum antibiotic and increases feed-utilization efficiency in animals.
    Type: Grant
    Filed: November 16, 1983
    Date of Patent: December 24, 1985
    Assignee: Eli Lilly and Company
    Inventors: Ronald D. Johnson, Ralph E. Kastner, LaVerne D. Boeck
  • Process for production of A-51568B antibiotic
    Patent number: 4558008
    Abstract: The novel glycopeptide antibiotic A-51568B is produced by submerged, aerobic fermentation of Nocardia orientalis NRRL 15232. A-51568B demonstrates antibiotic activity against gram-positive bacteria.
    Type: Grant
    Filed: December 13, 1983
    Date of Patent: December 10, 1985
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, Gary G. Marconi, Marvin M. Hoehn
  • Process for producing antibiotic A-51568 by fermentation and microorganism
    Patent number: 4558009
    Abstract: Antibiotic A-51568 is produced by submerged, aerobic fermentation of new Nocardia orientalis NRRL 15232. The antibiotic is effective against gram-positive organisms.
    Type: Grant
    Filed: December 27, 1983
    Date of Patent: December 10, 1985
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, Marvin M. Hoehn, Gary G. Marconi
  • Glycopeptide antibiotic CUC/CSV and process for its production
    Patent number: 4537715
    Abstract: New glycopeptide antibiotic CUC/CSV which has the formula: ##STR1## wherein R is L-ristosaminyl;R.sub.1 is the disaccharide mannosyl-glucosyl; andR.sub.2 and R.sub.3 are mannosyl, and its salts, particularly the pharmaceutically acceptable salts, are useful new antibiotics are active against gram-positive bacteria and increase feed-efficiency utilization and enhance milk production in ruminants.
    Type: Grant
    Filed: October 21, 1983
    Date of Patent: August 27, 1985
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, Gladys M. Clem, Charles L. Hershberger, Marie T. Anderson, Karl H. Michel
  • Process for preparing tunicamycin
    Patent number: 4336333
    Abstract: Tunicamycin is produced by the cultivation of Streptomyces chartreusis Calhoun and Johnson, 1956, NRRL 12338. Methods of recovering tunicamycin and for separating and isolating individual factors A.sub.1, A.sub.2, B.sub.1, B.sub.2, C.sub.1, C.sub.2, D.sub.1 and D.sub.2 from tunicamycin complex are described.
    Type: Grant
    Filed: March 13, 1981
    Date of Patent: June 22, 1982
    Assignee: Eli Lilly and Company
    Inventors: Robert L. Hamill, Marvin M. Hoehn, LaVerne D. Boeck
  • Method of producing the A-30912 antibiotics
    Patent number: 4288549
    Abstract: The microorganism Aspergillus nidulans var. roseus NRRL 11440 and the method of producing the A-30912 antibiotics by submerged aerobic fermentation of this microorganism to give the A-42355 antibiotic complex. A-30912 factors A, B, D, and H are separated from the A-42355 complex by chromatography. The A-42355 complex and A-30912 factors A, B, D, and H are antifungal agents.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: September 8, 1981
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, Ralph E. Kastner
  • Antibiotic A-28086 recovery process
    Patent number: 4009262
    Abstract: Recovery of an antibiotic selected from the group consisting of antibiotic A-28086 factor A, antibiotic A-28086 factor B, antibiotic A-28086 factor D, and salinomycin by acidifying the fermentation broth in which said antibiotic is produced to about pH 2.0-4.0 and separating the antibiotic with the culture solids.
    Type: Grant
    Filed: April 21, 1975
    Date of Patent: February 22, 1977
    Assignee: Eli Lilly and Company
    Inventors: LaVerne D. Boeck, David H. Berg