Patents by Inventor Lawrence E. Crooks

Lawrence E. Crooks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4599565
    Abstract: An imaging NMR scanner generates multi-dimensional NMR spin echo responses from selected sub-volumes of an object. 90.degree. and 180.degree. r.f. nutation pulses are used together with a variable amplitude gradient between these nutation pulses to phase encode a second dimension in the spin echo response which is already phase-encoded in a first dimension by use of a magnetic gradient during signal readout. Two-dimensional Fourier transforms or multiple angle projection reconstruction processes are then used to generate an array of pixel value data signals representing a visual image of the point-by-point spatial distribution of nutated nuclei within the object. Image artifacts potentially caused by relatively moving elements of the object are avoided by selecting the spin echo generating sub-volumes to avoid the moving elements. High resolution images of sub-volumes of interest can be obtained by selection of a sub-volume of interest in conjunction with these reconstruction techniques.
    Type: Grant
    Filed: July 19, 1983
    Date of Patent: July 8, 1986
    Assignee: The Regents of the University of Calif.
    Inventors: John C. Hoenninger, III, Lawrence E. Crooks, Mitsuaki Arakawa, Jerome R. Singer
  • Patent number: 4471305
    Abstract: An imaging NMR scanner obtains plural spin echo signals during each of successive measurement cycles permitting determination of the T2 parameter for each display pixel after but a single measurement sequence. The amplitude of the NMR spin echo responses is dependent on an "a" machine parameter (the elapsed time between initiation of a given measurement cycle and the occurrence of the NMR response) and upon a "b" machine parameter (the elapsed time between initiation of successive measurement cycles). These a and b machine time parameters are selectively controlled to enhance resultant image contrast between different types of tissue or other internal structures of an object under examination. Special phase control circuits ensure the repeatability of relative phasing between successive NMR responses from the same measured volume and/or of reference RF signals utilized to frequency translate and synchronously demodulate the NMR responses in the successive measurement cycles of a complete measurement sequence.
    Type: Grant
    Filed: December 15, 1981
    Date of Patent: September 11, 1984
    Assignee: The Regents of the University of Calif.
    Inventors: Lawrence E. Crooks, John C. Hoenninger, III, Mitsuaki Arakawa
  • Patent number: 4318043
    Abstract: Densities of resonant nuclei within elemental volumes along a line are measured using the nuclear magnetic resonance phenomenon called "spin echo". A first planar volume of nuclei is selectively excited to nutate spins by approximately 90.degree.. Thereafter a second planar volume of nuclei, transverse to the first planar volume, is selectively excited to nutate spins by approximately 180.degree.. The nuclei in the line volume common to both of the planar volumes thereafter generate characteristic spin echo signals. A magnetic gradient is established along this line volume during the spin echo read out so that the resultant spin echo signals can be processed to determine the respective densities of resonant nuclei along the line volume. Appropriate phasing of the excitations enables interference with the spin echo signals by the free induction decay to be eliminated. To enable rapid development, successive line volumes are read out which do not lie in previously excited planes.
    Type: Grant
    Filed: February 12, 1980
    Date of Patent: March 2, 1982
    Assignee: The Regents of the University of California
    Inventors: Lawrence E. Crooks, John C. Hoenninger, III, Mitsuaki Arakawa
  • Patent number: 4297637
    Abstract: Densities of resonant nuclei within elemental volumes along a line are measured using the nuclear magnetic resonance phenomenon called "spin echo." A first planar volume of nuclei is selectively excited to nutate spins by approximately 90.degree.. Thereafter a second planar volume of nuclei, transverse to the first planar volume, is selectively excited to nutate spins by approximately 180.degree.. The nuclei in the line volume common to both of the planar volumes thereafter generate characteristic spin echo signals. A magnetic gradient is established along this line volume during the spin echo read out so that the resultant spin echo signals can be processed to determine the respective densities of resonant nuclei along the line volume. Special pulsing sequences for rapidly effecting measurement of successive multiple line volumes and suitable apparatus for effecting such sequences are also described.
    Type: Grant
    Filed: July 20, 1978
    Date of Patent: October 27, 1981
    Assignee: The Regents of the University of California
    Inventors: Lawrence E. Crooks, John C. Hoenninger, III, Mitsuaki Arakawa