Abstract: A semi-trailer is assembled by constructing a semi-trailer body at a remote location. The semi-trailer body is transported from the remote location to an originating port by highway or rail and loaded onto a vessel by lifting the semi-trailer body using a plurality of upper female ISO connection points. The semi-trailer body is arranged in a stacked configuration on the vessel using the upper female ISO connection points and vertical load carrying members. The semi-trailer body is unloaded from the vessel at a destination port and a running gear assembly, a landing gear assembly, and a rear under-ride guard are attached to form an assembled semi-trailer.