Abstract: Described herein are crystalline forms of (R)-3-(2-(trans-4-(2-aminoethylamino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid. In some embodiments, the crystalline forms are formulated for treating a subject in need thereof with a bacterial infection.

Abstract: Described herein are crystalline forms of (R)-3-(2-(trans-4-(2-aminoethylamino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid. In some embodiments, the crystalline forms are formulated for treating a subject in need thereof with a bacterial infection.

Abstract: Disclosed herein are crystalline forms of ((2-Ethylbutanoyl)oxy)methyl (R)-2-hydroxy-3-propionamido-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylate. Also disclosed herein are methods of treating a bacterial with a crystalline form of ((2-Ethylbutanoyl)oxy)methyl (R)-2-hydroxy-3-propionamido-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylate.

Abstract: The present invention relates to pharmaceutical compositions containing boron-containing compounds and their use as inhibitors of beta-lactamase enzymes and as antibacterial agents in combination with a beta-lactam antibiotic.

Abstract: A magnetic toy construction block includes an inner shell and an outer shell which are arranged to form a module having a shell-within-a-shell construction. Disc-shaped magnets are rotatably received and maintained in pockets formed in the inner shell of the module. The inner shell is permanently housed within the outer shell such that the magnets lie in close proximity to its sidewalls and hence sidewalls of the module itself.

Abstract: Described herein are crystalline forms of (R)-3-(2-(trans-4-(2-aminoethylamino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid. In some embodiments, the crystalline forms are formulated for treating a subject in need thereof with a bacterial infection.

Abstract: A magnetic toy construction block has an interior configured to house a radially magnetized ring magnet, which is rotatably supported within the block by a pair of pedestals extending into the interior of the block from opposite ends thereof. The positions of the poles of the ring magnet are variable relative to the sides of the block in response to the rotation of the ring magnet.

Abstract: An amusement device includes a housing and a light unit positioned on the housing. A mounting ring is rotatably positioned on the housing, encircling the light unit. The amusement device also includes a rotatable, dome-shaped cover sized and shaped so as to be mounted on the mounting ring for conjoint rotation therewith. The rotatable, dome-shaped cover has an outer hemispherical surface adapted for covering the light unit and for placement of markings thereon. The light unit is adapted to illuminate the rotatable cover and any markings placed thereon. A motor unit is positioned in the housing for rotating the mounting ring and hence the cover and any markings thereon. Optionally, the amusement device may be provided with a stationary, dome-shaped cover having an outer hemispherical surface which is sized and shaped so as to be positioned over the rotatable cover and in spaced relationship thereto.

Abstract: Described herein are crystalline forms of (R)-3-(2-(trans-4-(2-aminoethylamino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid. In some embodiments, the crystalline forms are formulated for treating a subject in need thereof with a bacterial infection.

Abstract: A magnetic toy construction block has an interior configured to house a radially magnetized ring magnet, which is rotatably supported within the block by a pair of pedestals extending into the interior of the block from opposite ends thereof. The positions of the poles of the ring magnet are variable relative to the sides of the block in response to the rotation of the ring magnet.

Abstract: A magnetic toy construction block includes an inner shell and an outer shell which are arranged to form a module having a shell-within-a-shell construction. Disc-shaped magnets are rotatably received and maintained in pockets formed in the inner shell of the module. The inner shell is permanently housed within the outer shell such that the magnets lie in close proximity to its sidewalls and hence sidewalls of the module itself.

Abstract: An amusement device includes a housing and a light unit positioned on the housing. A mounting ring is rotatably positioned on the housing, encircling the light unit. The amusement device also includes a rotatable, dome-shaped cover sized and shaped so as to be mounted on the mounting ring for conjoint rotation therewith. The rotatable, dome-shaped cover has an outer hemispherical surface adapted for covering the light unit and for placement of markings thereon. The light unit is adapted to illuminate the rotatable cover and any markings placed thereon. A motor unit is positioned in the housing for rotating the mounting ring and hence the cover and any markings thereon. Optionally, the amusement device may be provided with a stationary, dome-shaped cover having an outer hemispherical surface which is sized and shaped so as to be positioned over the rotatable cover and in spaced relationship thereto.

Abstract: Described herein are crystalline forms of (R)-3-(2-(trans-4-(2-aminoethylamino)cyclohexyl)acetamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid. In some embodiments, the crystalline forms are formulated for treating a subject in need thereof with a bacterial infection.

Abstract: A module for a toy construction kit includes an elongated, monolithic body made from a non-magnetic material and having a central section, a pair of opposed ends, and a pair of tapered neck sections, one of which is positioned between the central section and one end of the body and the other of which is positioned between the central section and the other end of the body. One end of the body is at least partially covered by a pair of dome-shaped shells positioned on opposed sides thereof. The other end of the body is at least partially covered by another pair of dome-shaped shells positioned on diametrically opposed sides thereof. Each one of the shells is made from a magnetic material and is provided with a receptacle for receiving a plug of the non-magnetic material which forms a corresponding end of the body to thereby secure the shells to the body when the body and shells are integrated by way of a co-molding process.

Abstract: An activator formulation is disclosed for use in making an entertaining slime product. The activator includes water, a glycerol and/or a glycol, triethanolamine and a preservative. Glycols such as propylene glycol are suitable, while glycerols such as glycerin are appropriate. When added to a mixture of water and glue and then manually manipulated, an amusing play gel can be formed safely and quickly.

Abstract: The present disclosure relates to toy construction kits and assemblies and, more particularly, to connectors that are mechanically attached to and extend from the corners of geometric frame-like modules. The connectors are also adapted to interface with and magnetically connect to linear magnetic modules, whereby a user can create multiple construction platforms upon which a number of diverse and interesting structures can be assembled.

Abstract: The present disclosure relates to a magnetic module assembly having opposing geometric frames and a plurality of connector struts that connect and extend between the geometric frames. Each of the geometric frames has a plurality of segments, with each segment having a magnet enclosure integrated in the segment. The segments are interposed between attachment points formed in the geometric frame, each attachment point having a pair of receptacles that are sized and shaped to receive a corresponding pair of connector pins from a connector strut. The segments of a geometric frame have a larger thickness compared to that of the attachment points, making the attachment points of the frame frangible.

Abstract: A module for a toy construction kit includes an elongated, monolithic body made from a non-magnetic material and having a central section, a pair of opposed ends, and a pair of tapered neck sections, one of which is positioned between the central section and one end of the body and the other of which is positioned between the central section and the other end of the body. One end of the body is at least partially covered by a pair of dome-shaped shells positioned on opposed sides thereof. The other end of the body is at least partially covered by another pair of dome-shaped shells positioned on diametrically opposed sides thereof. Each one of the shells is made from a magnetic material and is provided with a receptacle for receiving a plug of the non-magnetic material which forms a corresponding end of the body to thereby secure the shells to the body when the body and shells are integrated by way of a co-molding process.