Abstract: The use of a genetic method to down-regulate RBO/EFR3/EFR3A/EFR3B proteins, TTC7 protein or PI4KIII? enzyme protein which interacts with RBO/EFR3/EFR3A/EFR3B proteins and TTC7 protein, or the use of a drug to inhibit PI4KIII? protein kinase activity reduces the accumulation of A?42 within neurons and age-dependent synaptic transmission failure and other obstacles in a fruit fly AD model, and obtains an effect of improving the learning and memory abilities of AD model mice. Provided is a method for using an RBO/EFR3/EFR3A/EFR3B inhibitor, a TTC7 inhibitor and a PI4KIII? inhibitor to treat Alzheimer's disease. Also provided is a method for screening a drug treating Alzheimer's disease by whether A? secretion by nerve cells is promoted or not.

Abstract: A method may include determining a combination of values of attributes represented by reference data associated with computing devices by training a machine learning model based on an association between (i) respective values of the attributes and (ii) the computing devices entering a device state. The combination may be correlated with entry into the device state. The method may also include selecting a subset of the computing devices that is associated with the combination of values. The method may additionally include determining a first rate at which computing devices of the subset have entered the device state during a first time period and a second rate at which one or more computing devices associated with the combination have entered the device state during a second time period, and generating an indication that the two rates differ.

Abstract: The present disclosure relates to the field of screw pump technologies, and in particular to a rotary mold extrusion molding process of a screw pump rotor. The rotary mold extrusion molding process of a screw pump rotor includes: performing isothermal spheroidizing annealing for a metal embryo material after treating the metal embryo material ultrasonically for 8˜30 s; performing cylindrical turning for the annealed metal embryo material and then performing sand-blasting, and soaking the metal embryo material in saponified oil for 10˜30 min for lubrication treatment, where the saponified oil contains a nano-silicon carbide of 0.5%˜8% which is a nano-silicon carbide mixture with particle sizes of 20˜60 nm and 140˜200 nm with a mixed weight ratio of 1:(2.8˜4); at room temperature, placing the metal embryo material into an extrusion cylinder to perform rotary mold extrusion molding so as to obtain a finished product.

Abstract: A transparent plate includes: a grating structure layer, including a first surface and a second surface opposite to each other, where a grating structure is disposed on the first surface; and a micro-texture layer, disposed on the second surface, where a surface of the micro-texture layer away from the second surface includes a plurality of micro-texture stripes, and light interferes between the grating structure and the micro-texture layer and forms moire stripes.

Abstract: A method and apparatus for training an information adjustment model of a charging station, an electronic device, and a storage medium are provided. An implementation comprises: acquiring a battery charging request, and determining environment state information corresponding to each charging station in a charging station set; determining, through an initial policy network, target operational information of each charging station in the charging station set for the battery charging request, according to the environment state information; determining, through an initial value network, a cumulative reward expectation corresponding to the battery charging request according to the environment state information and the target operational information; training the initial policy network and the initial value network by using a deep deterministic policy gradient algorithm; and determining the trained policy network as an information adjustment model corresponding to each charging station.

Abstract: In an approach to generating and using a sentence model for answer generation, one or more computer processors ingest a first corpus of a plurality of text sentences. One or more computer processors convert the plurality of text sentences into a plurality of sentence vectors. One or more computer processors group the plurality of sentence vectors into a plurality of sentence clusters, wherein a sentence cluster is composed of sentences that are semantically similar. One or more computer processors receive a second corpus. One or more computer processors determine, for each sentence cluster of the plurality of sentence clusters, a frequency each sentence cluster appears in the second corpus. Based on the determined frequency, one or more computer processors calculate a probability of each sentence cluster of the plurality of sentence clusters. Based on the calculated probabilities, one or more computer processors generate a first sentence model.

Abstract: A method and apparatus for automatically measuring and storing a various measured values of an item, or a sequence of measured values of one or more item(s) suitable for single-handed use by a user. In particular, the present invention relates to a mobile computing device with one or more sensors for determining when to measure and record a particular value of one or more items. The mobile computing device may automatically measure the values based on sensing a change in the temperature value or through using proximity as detected by one or more onboard sensors. Additionally, the mobile computing device may automatically measure the values based on coming within range of an external proximity device. In response to automatically measuring the values, the measured values are stored along with additional information for record keeping purposes.

Abstract: The present disclosure relates to the field of screw pump technologies, and in particular to a rotary mold extrusion molding process of a screw pump rotor. The rotary mold extrusion molding process of a screw pump rotor includes: performing isothermal spheroidizing annealing for a metal embryo material after treating the metal embryo material ultrasonically for 8˜30 s; performing cylindrical turning for the annealed metal embryo material and then performing sand-blasting, and soaking the metal embryo material in saponified oil for 10˜30 min for lubrication treatment, where the saponified oil contains a nano-silicon carbide of 0.5%˜8% which is a nano-silicon carbide mixture with particle sizes of 20˜60 nm and 140˜200 nm with a mixed weight ratio of 1:(2.8˜4); at room temperature, placing the metal embryo material into an extrusion cylinder to perform rotary mold extrusion molding so as to obtain a finished product.

Abstract: An approach is provided for a gaming overlay application to provide automatic in-game subtitles and/or closed captions for video game applications. The overlay application accesses an audio stream and a video stream generated by an executing game application. The overlay application processes the audio stream through a text conversion engine to generate at least one subtitle. The overlay application determines a display position to associate with the at least one subtitle. The overlay application generates a subtitle overlay comprising the at least one subtitle located at the associated display position. The overlay application causes a portion of the video stream to be displayed with the subtitle overlay.

Abstract: Disclosed is a framework for providing microservices for database with embedded container service in a container cloud platform. The framework includes a container cloud manager for performing distributed management of resources in a data center. The container cloud manager includes an orchestrator with a flexible job scheduler and operator pool. The flexible job scheduler and container cloud master form a flexible job management platform for managing jobs of the data center. The flexible job management framework can isolate various types of jobs as well as mix various jobs for efficient usage of hosts or resources in the data center. The operator pool includes optional components of a database. The orchestrator facilitates quick customization and release of database products, such as a HANA database with optional services, as requested by a user in the container cloud platform.

Abstract: Methods, systems, and computer-readable storage media for receiving, by a cross-process scheduling engine executed within a cloud platform, work scenario metadata and sensitivity metadata, generating, by the cross-process scheduling engine, a lineage graph representing relationships between one or more of data and processes to be executed for a work scenario represented by the work scenario metadata, defining, by the cross-process scheduling engine, a set of tile segments for the work scenario based on the lineage graph and the sensitivity metadata, dispatching, by the cross-process scheduling engine, a first sub-set of tile segments for execution in a private deployment including one or more private nodes, and dispatching, by the cross-process scheduling engine, a second sub-set of tile segments for execution in a public deployment including one or more public nodes.

Abstract: In an example embodiment, a new solution is provided for an in-memory database provided in a cloud as a service that enables “job cross running” instead of “parallel job running.” Specifically, job scripts are clustered based on a shared service. A primary job script in the cluster is compiled and executed, but secondary job scripts in the cluster are not compiled until after the execution of the primary job script has begun. A mock library is inserted into each of the secondary job scripts to cause service calls for the shared service in the secondary job scripts to be replaced with mock service calls. The secondary job scripts are then scheduled and executed, and upon completion the primary job script is permitted to delete the shared service.

Abstract: The present disclosure provides a connection mode configuration method, a base station and a communication system. The configuration method includes: the CU-CP of the first base station determines a connection mode adopted by a UE after being switched to a second base station according to a UE capability of the UE and a connection mode supported by the CU-UP of the first base station, and sends a handover request to the second base station; the CU-CP indicates the CU-UP to update the bearer configuration according to the bearer configuration information included in the secondary base station adding request; the CU-CP generates the first access configuration information according to an updating result of the bearer configuration of the CU-UP and sends the first access configuration information to the second base station; the CU-CP indicates the CU-UP to update the bearer configuration according to the bearer configuration information.

Abstract: A large-width cathode roller for producing high-strength ultra-thin copper foil includes titanium side plates and a titanium cylinder sealed by the titanium side plates, and a cathode roller core penetrated through the titanium side plates. Steel-copper explosive clad cylinders and a steel support plate are disposed in/on the side plate, inner ring surfaces of the side plates and the copper plates are connected to a copper sleeve around the cathode roller core, outer ring surfaces of the copper plates and the steel support plates are connected to a copper cylinder, inner ring surfaces of the steel support plates are connected to the cathode roller core; and multiple electrically conductive support rings on the copper cylinder are connected to the copper plates on two sides through the electrically conductive copper bars to form a conducting loop to improve the distribution uniformity of the current on the surface of the cathode roller.

Abstract: The present disclosure provides a user plane data processing method and a base station. The method includes: each CU-UP determines a current service support capabilities according to first trigger information, and sends it to a CU-CP; the CU-CP selects a CU-UP for each service bearer of the UE according to the current service support capabilities of the each CU-UP if at least part of service bearers of the UE needs to be configured or updated according to second trigger information; the CU-CP sends first UP configuration information associated with the each service bearer to the UE and second UP configuration information associated with the each service bearer to the each CU-UP, thereby the UE determining whether to configure a PDCP status report according to the first UP configuration information, and each CU-UP determining whether to process the PDCP status report from the UE according to the second UP configuration information.

Abstract: A hot-spinning formation method for large-diameter titanium alloy cylindrical parts. A workblank is placed in a resistance furnace to heated to 600-650° C., is maintained at this temperature for 0.5-1 h and is then taken out of the resistance furnace; after the workblank is heated, the inner diameter of the workblank becomes larger; the heated workblank is installed on a mandrel, and spinning is started when a maximum clearance between the workblank and the mandrel is less than 0.5 mm; the mandrel and the spinning rollers do not need to be preheated, and a multi-pass spinning process is adopted, such that the workblank can deform more uniformly. A vertical spinning lathe is used for spinning, the mandrel is easy to change, and the workblank is easy to assemble and disassemble.

Abstract: The subject invention pertains to an evaporation strategy combined with low-molecular-weight polyacrylic acid (LPAA) to generate an antibacterial dental enamel-like structure. Polystyrene (PS) plates can be used as a removable substrate for the continuous growth of fluorapatite (FAP). The FAP-LPAA composition can be used to kill microorganisms. The LPAA contained dental enamel-like FAP provides an alternative to prevent secondary caries if a carious cavity is filled with shaped dental enamel-like FAP-LPAA.

Abstract: Methods for selectively depositing on self-assembled monolayer (SAM) are disclosed. Some embodiments of the disclosure utilize a precursor of a Formula (I), Formula (II), Formula (III), and Formula (IV): RnSi(NR?R?)(4-n) (III), RnSiX(4-n) (IV), wherein R1 and R2 are independently selected from substituted or unsubstituted C1-C20 alkyl, or R1 and R2 form a substituted or unsubstituted C1-C20 cycloalkyl ring, and wherein R3, R4, R5, R6, Rn are independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted C1-C20 alkoxy, and substituted or unsubstituted C1-C20 vinyl, X is a halide selected from Cl, Br, and I, and n is an integer from 1 to 3, to form a self-assembled monolayer (SAM) on a damaged silicon nitride layer to prevent critical dimension blow out of a feature in a silicon nitride layer substrate.

Abstract: The present disclosure provides a bone conduction based sound generating lollipop, a processing method and a system thereto. The bone conduction based sound generating lollipop includes a housing, a trigger, a controller and a sound generating component. The sound generating component, the controller and the trigger are integrated in a packaging cavity formed by the housing, and a separate packaging of the sound generating component is eliminated. When a supporting component of the housing enters a human oral cavity, the trigger sends an opening instruction to the controller, the controller drives the sound generating component to vibrate, and then a vibration signal is transmitted to a human auditory system in a bone conduction manner after passing through the supporting component of the housing and an edible object attached to the supporting component, and passing through an oral tissue or teeth of the human body.

Abstract: The present disclosure provides a bone conduction-based clamping device and processing method. The device includes a handle, a clamping structure provided on one side of the handle, and a sound generating processor provided inside the handle. A user puts food into his mouth cavity by clamping the food with the clamping structure, and a vibration signal generated by the sound generating processor is transmitted to the food by the clamping structure and then transmitted to the user’s auditory system by an oral tissue or teeth of the user, thereby avoiding the pressing feeling caused by wearing in a pressing manner. Putting the clamping structure into the user’s mouth cavity can also reduce sound leakage, improve sound quality and protect privacy. In addition, the food can be replaced by the clamping structure, thereby guaranteeing hygiene and health, improving the usage rate of the device, and realizing multi-user sharing.