Abstract: A package for a medical device such as an intermittent catheter has a case and a cap connected by threads. The case includes a hollow tube which is closed at one end and open at the other. A shoulder is formed near one end of the case. Above the shoulder is a cylindrical ferrule that includes external threads. The cap has internal threads selectably engageable with the threads on the ferrule to form a liquid-tight seal between the cap and case when the cap is installed on the case.

Abstract: The present disclosure generally relates to managing weather information. In some embodiments, methods and user interfaces for managing weather information are described. In some embodiments, methods and user interfaces for displaying daily weather information are described.

Abstract: A molded article suitable for subsequent blow-molding into a final-shaped container. The article includes a neck portion; a gate portion; and a body portion extending between the neck portion and the gate portion, at least a majority of the body portion having an overall shape which is symmetric about a body axis extending longitudinally through a center of the body portion. The body portion includes an inner exterior layer and an outer exterior layer of a first polymeric material; and a core layer of a second polymeric material disposed between the inner exterior layer and the outer exterior layer. A radial thickness or a material of the core layer is selectively varied to govern non-uniform blow molding of the molded article into the final-shaped container.

Abstract: A molded article suitable for subsequent blow-molding into a final-shaped container. The article includes a neck portion; a gate portion; and a body portion extending between the neck portion and the gate portion, at least a majority of the body portion having an overall shape which is symmetric about a body axis extending longitudinally through a center of the body portion. The body portion includes an inner exterior layer and an outer exterior layer of a first polymeric material; and a core layer of a second polymeric material disposed between the inner exterior layer and the outer exterior layer. A radial thickness or a material of the core layer is selectively varied to govern non-uniform blow molding of the molded article into the final-shaped container.

Abstract: The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to HbS modulators of formula (I) or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, R2 and R3 are as defined in the description. HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).

Abstract: The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to HbS modulators of formula (I) or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, R2 and R3 are as defined in the description. HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).

Abstract: The present disclosure generally relates to managing weather information. In some embodiments, methods and user interfaces for managing weather information are described. In some embodiments, methods and user interfaces for displaying daily weather information are described.

Abstract: A method, according to one embodiment, includes, at a server in communication with a database and a network, receiving from a user a link to an internet webpage, via the network, analyzing, by the server, a Rich Site Summary (RSS) feed of the internet webpage and text in the internet webpage, categorizing, by the server, the internet webpage into a predetermined category based on the RSS feed of the internet webpage and the text in the internet webpage, creating, by the server, a summary of the internet webpage, utilizing the RSS feed of the internet webpage and the text in the internet webpage, identifying, by the server, an image from the internet webpage, resizing, by the server, the image from the internet webpage to create a resized image, including, by the server, the resized image in the summary of the internet webpage, upon determining that the resized image has a minimum size, meets predetermined aspect ratio limits, and is not repeated within the predetermined category, and in a webpage associated w

Abstract: A shear band for a tire includes a first belt layer extending circumferentially around the tire, a second belt layer extending circumferentially around the tire, and a shear band radially interposed between the first belt layer and the second belt layer. The shear band includes a first reinforcing ply radially adjacent the first belt layer, a third reinforcing ply radially adjacent the second belt layer, and a second reinforcing ply radially interposed between the first reinforcing ply and the second reinforcing ply. The first reinforcing ply includes a first flattened, braided tube layer enclosed by a first rubber layer. The second reinforcing ply includes a second flattened, braided tube layer enclosed by a second rubber layer. The third reinforcing ply includes a third flattened, braided tube layer enclosed by a third rubber layer.

Abstract: A shear band for a tire includes a first belt layer extending circumferentially around the tire, a second belt layer extending circumferentially around the tire, and a shear band radially interposed between the first belt layer and the second belt layer. The shear band includes a first reinforcing ply radially adjacent the first belt layer, a third reinforcing ply radially adjacent the second belt layer, and a second reinforcing ply radially interposed between the first reinforcing ply and the second reinforcing ply. The first reinforcing ply includes a first flattened, braided tube layer enclosed by a first rubber layer. The second reinforcing ply includes a second flattened, braided tube layer enclosed by a second rubber layer. The third reinforcing ply includes a third flattened, braided tube layer enclosed by a third rubber layer.

Abstract: The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to HbS modulators of formula (I) or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, R2 and R3 are as defined in the description. HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).

Abstract: The disclosure provides a process for manufacturing a tread molding element configured to mold at least a portion of a tire tread, the process comprising the steps of modeling a three-dimensional shape of a tread molding element through a modeling program that can be recognized by a 3D printer; providing one or more plastic compositions comprising one or more thermoplastic polymers having a melting point of at least 180° C.; forming a tread molding element by 3D printing from the one or more plastic compositions; and optionally annealing the tread molding element.

Abstract: Dirac semimetals, methods for modulating charge carrying density and/or band gap in a Dirac semimetal, devices including a Dirac semimetal layer, and methods for forming a Dirac semimetal layer on a substrate are described.

Abstract: A shear band for a tire includes a first belt layer extending circumferentially around the tire, a second belt layer extending circumferentially around the tire, and a shear band radially interposed between the first belt layer and the second belt layer. The shear band includes a first reinforcing ply radially adjacent the first belt layer, a third reinforcing ply radially adjacent the second belt layer, and a second reinforcing ply radially interposed between the first reinforcing ply and the second reinforcing ply. The first reinforcing ply includes a first flattened, braided tube layer enclosed by a first rubber layer. The second reinforcing ply includes a second flattened, braided tube layer enclosed by a second rubber layer. The third reinforcing ply includes a third flattened, braided tube layer enclosed by a third rubber layer.

Abstract: A shear band for a tire includes a first belt layer extending circumferentially around the tire, a second belt layer extending circumferentially around the tire, and a shear band coupon radially interposed between the first belt layer and the second belt layer. The shear band coupon includes a first reinforcing ply radially adjacent the first belt layer, a third reinforcing ply radially adjacent the second belt layer, and a second reinforcing ply radially interposed between the first reinforcing ply and the second reinforcing ply. The first reinforcing ply includes a first three dimensional layer enclosed by a first fabric layer. The second reinforcing ply includes a second three dimensional layer enclosed by a second fabric layer. The third reinforcing ply includes a third three dimensional layer enclosed by a third fabric layer.

Abstract: A method of making a non-pneumatic tire, the non-pneumatic tire comprising a ground contacting annular tread portion comprising a tread rubber composition, a shear band comprising a cord reinforced rubber composition and disposed radially inward of the tread portion, and at least one spoke disk disposed radially inward of the shear band; wherein the spoke disk has an outer ring, and an inner ring, and a first and second spoke extending radially between the outer ring and the inner ring, wherein the first and second spokes are connected at a joint; the method comprising the steps of: applying a curable adhesive as an interface between a radially outermost surface of the spoke disk and a radially innermost surface of the shear band in its uncured state; assembling the tread portion in an uncured state, the shear band in an uncured state, and the at least one spoke disk to form an pre-assembly; and curing the pre-assembly.

Abstract: The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to HbS modulators of formula (I) or tautomers thereof, or pharmaceutically acceptable salts of said modulators or tautomers thereof, wherein X, Y, R2 and R3 are as defined in the description. HbS modulators are potentially useful in the treatment of a wide range of disorders, including sickle cell disease (SCD).

Abstract: A system determines average values for bending stiffness and shear rigidity of a shear band coupon.