Abstract: In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.

Abstract: In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.

Abstract: A microprojection array is provided, comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a vaccine and a polymeric material. The array may have multiple layers. The vaccine may be placed in only one layer. In another embodiment of the invention, a method of preventing a disease is provided, comprising insertion into the skin of a patient an array of microprojections comprising a layer which comprises a vaccine for that disease and a polymer.

Abstract: In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.

Abstract: In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.

Abstract: In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.

Abstract: A microprojection array is provided, comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a vaccine and a polymeric material. The array may have multiple layers. The vaccine may be placed in only one layer. In another embodiment of the invention, a method of preventing a disease is provided, comprising insertion into the skin of a patient an array of microprojections comprising a layer which comprises a vaccine for that disease and a polymer.

Abstract: A microprojection array is provided, comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a vaccine and a polymeric material. The array may have multiple layers. The vaccine may be placed in only one layer. In another embodiment of the invention, a method of preventing a disease is provided, comprising insertion into the skin of a patient an array of microprojections comprising a layer which comprises a vaccine for that disease and a polymer.

Abstract: A microneedle applicator is provided which has two roughly concentric portions which may be, for example, a solid disk and an annulus surrounding it. On the skin-facing side of the inner portion of the applicator a microneedle array is located. The outer portion of the applicator is placed against the skin, contacting it at a zone. The microneedle array is then pressed towards the skin.

Abstract: In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.

Abstract: A composition comprising a plurality of discrete carrier-swellable polymer particles (preferably polyNIPAM particles) and a corresponding carrier (e.g. water), which particles have a low polydispersity index and are present in an amount of at least 0.1% by weight of the composition may be used to impart structural-image properties (such as structural colour) to a substrate by coating or printing methods. Additional benefits of adherence to low-energy surface substrates and enhanced rheological properties for printing compositions may also be provided. The compositions and methods used in the invention allow visual effects or security applications to be incorporated into substrates in a low-cost and convenient manner.

Abstract: This Pole Universal Drainage Bag Holder (U.D.B.H.) is formed from two molded unitary suitable polymeric materials (2) pivoting at its midpoint (Fig. H). It works as a collaboration of the following parts: The Clamp Front Opening (Fig. J.), the Middle Holding Section (Fig. I) and the Clamp Handles (Fig. H). The clamp front opening (1) and (2a) (Fig-J), is used to hold a catheter or I.V. bag or a drainage bag any general size. The Middle Holding Section (Fig. I) of the (U.D.B.H.) has an interior diameter coated with suitable synthetic polymeric material (2a) allowing the (U.D.B.H.) to clasp and hold firmly onto I.V. pole or object similar (i.e. Bedside pole) and is designed to hold both the weight of (U.D.B.H.) and the drainage bag and itself. The Clamp Handles (Fig. H) used to open and close the device and is held in place by a pivoting spiral coil (4).

Abstract: A microprojection array is provided, comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a vaccine and a polymeric material. The array may have multiple layers. The vaccine may be placed in only one layer. In another embodiment of the invention, a method of preventing a disease is provided, comprising insertion into the skin of a patient an array of microprojections comprising a layer which comprises a vaccine for that disease and a polymer.

Abstract: In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.

Abstract: A microneedle applicator is provided which has two roughly concentric portions which may be, for example, a solid disk and an annulus surrounding it. On the skin-facing side of the inner portion of the applicator a microneedle array is located. The outer portion of the applicator is placed against the skin, contacting it at a zone. The microneedle array is then pressed towards the skin.

Abstract: An article retention band includes a ring, a lever, and a clasp. The ring has an inner circumference and is configured to encircle and apply a compressive force around an exterior circumference of an article. The lever is attached to the ring and has an end surface. The lever is moveable between a first position in which the end surface is spaced from the ring and a second position in which the end surface is adjacent to the ring. Movement of the lever from the first position to the second position results in a reduction of the inner circumference of the ring. A clasp is configured for selectively retaining the lever in the second position such that the clasp at least partially covers the end surface of the lever. A drive assembly and a vehicle having a drive assembly are also provided.

Abstract: A protective cover for the underside of a vehicle is formed substantially from plastic and can provide a skid plate for the vehicle. The protective cover includes at least one fastening portion which is configured to facilitate attachment of the protective cover to the vehicle. In one embodiment, the protective cover includes a rib that is movable to matingly contact a feature on an underside of a vehicle so that loading from an impact is distributed in a predetermined manner. In another embodiment, the fastening portion includes an abutment wall that substantially transmits a shearing load from the protective cover to a vehicle. In yet another embodiment, the fastening portion is adjacent to an edge portion of the protective cover. The protective cover may be included in a vehicle.

Abstract: A suspension arm is configured for pivotable attachment to a vehicle's frame and for at least partially supporting a wheel knuckle. The suspension arm includes first and second elongated support members which each have proximal and distal ends. The suspension arm also includes a bracket formed from sheet metal. The support arm is configured for pivotable attachment to a vehicle's frame adjacent to the proximal ends of the first and second elongated support members. The distal ends of the first and second elongated support members are attached to the bracket. The bracket defines an opening configured for receiving a wheel knuckle. A pair of suspension arms and a vehicle having first and second suspension arms are also provided.

Abstract: The device is exactly 3.7187 inches in length and made from a metal material. There are two circular areas positioned in a row on one end running length ways on the device. The outside diameter both circles measure 0.7900 of an inch. The inside diameter of both circles measures 0.5900 of an inch. Positioned directly on top of each circular area will be a thin small white solid plastic circular disc. The outside diameter of each disc equals that of the circles. The stem or long thin middle area of the device measures 0.1000 in width. Positioned at the opposite end of the device will be a ½ inch in diameter button magnet. This magnet will be attached to a small circle of metal measuring 0.5000 of an inch in diameter.