Abstract: Disclosed are 2,8-diazaspiro[4.5]decane compounds, including (pyrido[3,4-d]pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane compounds, (2,6-naphthyridin-1-yl)-2,8-diazaspiro[4.5]decane compounds, and (1,7-naphthyridin-4-yl)-2,8-diazaspiro[4.5]decane compounds, that are inhibitors of LATS1/2, compositions containing these compounds, and methods for inhibiting LATS1/2 activity.

Abstract: Concepts and technologies disclosed herein are directed to machine learning model understanding as-a-service. According to one aspect of the concepts and technologies disclosed herein, a model understanding as-a-service system can receive, from a user system, a service request that includes a machine learning model created for a user associated with the user system. The model understanding as-a-service system can conduct an analysis of the machine learning model in accordance with the service request. The model understanding as-a-service system can compile, for the user, results of the analysis of the machine learning model in accordance with the service request. The model understanding as-a-service system can create a service response that includes the results of the analysis. The model understanding as-a-service system can provide the service response to the user system.

Abstract: Devices, computer-readable media, and methods for providing an enhanced indication of an object that is located via a visual feed in accordance with a user context are disclosed. For instance, in one example, a processing system including at least one processor may detect a user context from a visual feed, locate an object via the visual feed in accordance with the user context, and provide an enhanced indication of the object via an augmented reality display.

Abstract: A method for determining discharge area in hydraulic stimulation operations is provided that includes obtaining one or more treatment data inputs from a well system, and determining a discharge area by applying the one or more treatment data inputs to a function that determines discharge area in terms of volumetric flow rate of the fracturing fluid, wherein the discharge area is a total area of all downhole exits through which the fracturing fluid exits a wellbore into a subterranean formation.

Abstract: The present invention provides compositions comprising a recombinant AAV and one or more pharmaceutically acceptable excipients. The compositions have improved stability and shelf life as compared to other AAV compositions.

Abstract: A forestry machine includes a ground propulsion apparatus, a chassis supported by the ground propulsion apparatus, a cab, an engine and a work implement. The chassis includes a front chassis portion and a rear chassis portion. The front chassis portion includes an upper portion and a lower portion. The rear chassis portion has a wood basket supported thereon. The cab is rotatably supported on the front chassis portion by a rotatable connection about a cab rotation axis to be selectively rotated 360 degrees. The engine is integrated into the front chassis portion. At least a part of the engine is disposed below an upper most surface of the upper portion. The work implement is movably attached to the cab. The work implement includes a boom movably attached to the cab, an arm movably attached to the boom, and a work tool attached to the arm.

Abstract: In some embodiments, a device is adapted to conduct social network application (SNA) operations and other application operations by a user. The device includes a processor and a group of applications. The group of applications that are functionally linked on the device by sharing access to one or more common resources stored in memory of the device, wherein the one or more common resources are used by software code of the device to coordinate related application activities between respective applications of the group of applications, and, wherein the group of applications are configured during operation to communicate user activity data indicative of contemporaneous user engagement for a given application on the device during a corresponding application session to at least one server for tracking user activity across the group of applications on an integrated basis for the user of the device.

Abstract: In one embodiment, a method of sharing locations of users participating in a social networking service at a geographic location and communicating app related information of users participating in the social networking service, the method executed by a computer system and comprises: receiving location information and text descriptive information from a mobile device of a first user of the social networking service, the location information representing a geographic location of the first user, the text descriptive information manually provided by the first user on an input module of the mobile device; associating the location information with the text descriptive information of the first user in a database; sending the text descriptive information and the location information of the first user to a second user for display.

Abstract: A forestry machine includes a ground propulsion apparatus, a chassis supported by the ground propulsion apparatus, a cab, an engine and a work implement. The chassis includes a front chassis portion and a rear chassis portion. The front chassis portion includes an upper portion and a lower portion. The rear chassis portion has a wood basket supported thereon. The cab is rotatably supported on the front chassis portion by a rotatable connection about a cab rotation axis to be selectively rotated 360 degrees. The engine is integrated into the front chassis portion. At least a part of the engine is disposed below an upper most surface of the upper portion. The work implement is movably attached to the cab. The work implement includes a boom movably attached to the cab, an arm movably attached to the boom, and a work tool attached to the arm.

Abstract: In one embodiment, a method of sharing locations of users participating in a social networking service at a geographic location and communicating app related information of users participating in the social networking service, the method executed by a computer system and comprises: receiving location information and text descriptive information from a mobile device of a first user of the social networking service, the location information representing a geographic location of the first user, the text descriptive information manually provided by the first user on an input module of the mobile device; associating the location information with the text descriptive information of the first user in a database; sending the text descriptive information and the location information of the first user to a second user for display.

Abstract: In one embodiment, a method of sharing locations of users participating in a social networking service at a geographic location and communicating app related information of users participating in the social networking service, the method executed by a computer system and comprises: receiving location information and text descriptive information from a mobile device of a first user of the social networking service, the location information representing a geographic location of the first user, the text descriptive information manually provided by the first user on an input module of the mobile device; associating the location information with the text descriptive information of the first user in a database; sending the text descriptive information and the location information of the first user to a second user for display.

Abstract: A wall-mounting brace for mirrors, artwork, and similar objects is a device that is utilized to secure an object such as a mirror to a surface such as a wall. The device features an elongated brace that is used to hold the top of the mirror to the wall while the bottom of the mirror is held in place with a fastener such as a J-channel. A plurality of fastener holes present on a mounting plate of the elongated brace is utilized to secure the elongated brace to the surface. The mirror is held in place on the surface by a retention plate and a connector plate of the elongated brace. A cover plate is utilized to selectively cover and uncover the plurality of fastener holes. The cover plate may be hingedly attached to the elongated brace or removable from the elongated brace altogether.

Abstract: A wall-mounting brace for mirrors, artwork, and similar objects is a device that is utilized to secure an object such as a mirror to a surface such as a wall. The device features an elongated brace that is used to hold the top of the mirror to the wall while the bottom of the mirror is held in place with a fastener such as a J-channel. A plurality of fastener holes present on a mounting plate of the elongated brace is utilized to secure the elongated brace to the surface. The mirror is held in place on the surface by a retention plate and a connector plate of the elongated brace. A cover plate is utilized to selectively cover and uncover the plurality of fastener holes. The cover plate may be hingedly attached to the elongated brace or removable from the elongated brace altogether.

Abstract: In one embodiment, a method of sharing locations of users participating in a social networking service at a geographic location and communicating app related information of users participating in the social networking service, the method executed by a computer system and comprises: receiving location information and text descriptive information from a mobile device of a first user of the social networking service, the location information representing a geographic location of the first user, the text descriptive information manually provided by the first user on an input module of the mobile device; associating the location information with the text descriptive information of the first user in a database; sending the text descriptive information and the location information of the first user to a second user for display.