Abstract: A system for forming horizontally stacked groups of containers includes an infeed screw set, an orienting screw set, and a grouping mechanism. Containers are presented to the infeed screw in a vertical orientation, and are progressed from the infeed screw set to the orienting screw set via a transitioning pocket defined by overlapping pockets of the infeed and orienting screw sets. As containers are progressed through the orienting screw the containers are rotated via a series of orienting pockets to a horizontal orientation and progressed via a series of nesting pockets to form a series of horizontally nested containers. The series is discharged to a grouping mechanism which separates a predefined number of containers from the series to form a horizontally stacked group, which is outfed from the stacking system.

Abstract: A system for forming horizontally stacked groups of containers includes an infeed screw set, an orienting screw set, and a grouping mechanism. Containers are presented to the infeed screw in a vertical orientation, and are progressed from the infeed screw set to the orienting screw set via a transitioning pocket defined by overlapping pockets of the infeed and orienting screw sets. As containers are progressed through the orienting screw the containers are rotated via a series of orienting pockets to a horizontal orientation and progressed via a series of nesting pockets to form a series of horizontally nested containers. The series is discharged to a grouping mechanism which separates a predefined number of containers from the series to form a horizontally stacked group, which is outfed from the stacking system.

Abstract: The present disclosure is directed to compositions comprising blended materials comprising a substantially crystalline HCV nucleotide polymerase inhibitor; a first solid dispersion formulation, which comprises an HCV NS5a inhibitor or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable polymers or a mixture thereof, and optionally one or more pharmaceutically acceptable surfactants or a mixture thereof, and optionally one or more excipients, and a second solid dispersion formulation, which comprises an HCV NS3 inhibitor or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable polymers or a mixture thereof, and optionally one or more pharmaceutically acceptable surfactants or a mixture thereof, and optionally one or more excipients.

Abstract: The present disclosure is directed to compositions comprising blended materials comprising a substantially crystalline HCV nucleotide polymerase inhibitor; a solid dispersion formulation, which comprises an HCV NS5a inhibitor or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable polymers or a mixture thereof, and optionally one or more pharmaceutically acceptable surfactants or a mixture thereof; and optionally one or more pharmaceutically acceptable surfactants or a mixture thereof; and optionally one or more excipients.

Abstract: The present disclosure is directed to compositions comprising blended materials comprising a substantially crystalline HCV nucleotide polymerase inhibitor; a first solid dispersion formulation, which comprises an HCV NS5a inhibitor or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable polymers or a mixture thereof; and optionally one or more pharmaceutically acceptable surfactants or a mixture thereof; and optionally one or more excipients; and a second solid dispersion formulation, which comprises an HCV NS3 inhibitor or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable polymers or a mixture thereof; and optionally one or more pharmaceutically acceptable surfactants or a mixture thereof; and optionally one or more excipients.

Abstract: A gripper formed as a single component includes a hoop portion connecting facing arms. Each arm may have a tang end, a jaw end and a pivot intermediate the tang and jaw ends and be attached to the hoop portion at the pivot to be pivotable to change the size of a jaw opening defined by the jaw ends. The hoop portion is cyclically loaded in use and configured to act as a stress concentrator for the gripper and provide a failure point for consistently initiating a failure crack in the hoop portion at time of failure of the gripper. Each of the facing arms is attachable to a base such that at failure, the fractured portions of the gripper are retained to the base.

Abstract: A gripper formed as a single component includes a hoop portion connecting facing arms. Each arm may have a tang end, a jaw end and a pivot intermediate the tang and jaw ends and be attached to the hoop portion at the pivot to be pivotable to change the size of a jaw opening defined by the jaw ends. The hoop portion is cyclically loaded in use and configured to act as a stress concentrator for the gripper and provide a failure point for consistently initiating a failure crack in the hoop portion at time of failure of the gripper. Each of the facing arms is attachable to a base such that at failure, the fractured portions of the gripper are retained to the base.

Abstract: A gripper formed as a single component includes a hoop portion connecting facing arms. Each arm may have a tang end, a jaw end and a pivot intermediate the tang and jaw ends and be attached to the hoop portion at the pivot to be pivotable to change the size of a jaw opening defined by the jaw ends. The hoop portion is cyclically loaded in use and configured to act as a stress concentrator for the gripper and provide a failure point for consistently initiating a failure crack in the hoop portion at time of failure of the gripper. Each of the facing arms is attachable to a base such that at failure, the fractured portions of the gripper are retained to the base.