Abstract: Embodiments relate to a modified T cell comprising an antigen binding molecule, wherein expression and/or function of CDC42 in the modified cell has been enhanced. In embodiments, the modified cell has an increased level of cytokine release in response to an antigen that the antigen binding molecule binds as compared to a corresponding T cell that does not overexpress CDC42. In embodiments, the cytokine release comprises a cytokine release of IFN?. In embodiments, the modified cell has an enhanced migration capability in response to a chemokine as compared to a corresponding T cell that does not overexpress CDC42.

Abstract: Establishing a data store of content metadata includes receiving, from a content player executing on a client device, an indication of content played by the content player, the indication comprising one or more pieces of metadata associated with the content. It further includes selecting a set of one or more rules applicable to parsing the metadata associated with the content. It further includes processing the metadata at least in part by applying the selected parsing rules to at least a portion of the metadata associated with the content. It further includes storing, to a data store, at least some of the processed metadata associated with the content.

Abstract: The present invention discloses a right-angle turning method for small-diameter TBM exploration adit excavation and belongs to the field of geological exploration of water conservancy and hydropower projects.

Abstract: The compositions and methods described herein are directed to treating solid tumors using CAR T therapy and/or antibodies targeting GCC. The compositions include CAR comprising an extracellular domain that binds GCC.

Abstract: A building photovoltaic data interpolation method based on WGAN and whale optimization algorithm is provided, which includes: obtaining historical building roof photovoltaic output data, perform preprocessing on the historical building roof photovoltaic output data, and uses CNN to build a GAN; describing missing value position of preprocessed data by using a binary mask matrix, and setting Wasserstein distance to define a loss function of a GAN generator and a discriminator; taking the loss function as a fitness function, optimizing an input to the GAN generator through a whale optimization algorithm and obtaining optimized candidate samples; fusing the optimized candidate samples and a photovoltaic data processed by the binary mask matrix to obtain completed reconstructed samples, so as to improve the complementary accuracy, optimize the random noise, remove the unfavorable influencing components, and provide services for building rooftop PV data interpolation more accurately.

Abstract: An integrated semiconductor device includes a substrate, semiconductor circuit layers, a first insulating layer, a second insulating layer, and an interconnection layer. The semiconductor circuit layers are disposed above the substrate. The semiconductor circuit layers have device portions and isolating portions, and the isolating portions are located among the device portions. The first insulating layer is disposed on the semiconductor circuit layers, and the second insulating layer is disposed on the first insulating layer, and the interconnection layer is disposed on the semiconductor circuit layers. The interconnection layer penetrates the first and second insulating layers to electrically connect the device portions of the semiconductor circuit layers. The second insulating layer or the first and second insulating layers collectively form one or more isolating structures above the isolating portion of the semiconductor circuit layers.

Abstract: An integrated semiconductor device includes a substrate, semiconductor circuit layers, an insulating material, and an interconnection layer. The semiconductor circuit layers are disposed above the substrate. The semiconductor circuit layers have device portions and isolating portions, and the isolating portions are located among the device portions. The insulating material is disposed on the semiconductor circuit layers, and the interconnection layer is embedded in the insulating material and electrically connected to the semiconductor circuit layers. The isolating portions provide electrical isolation between adjacent device portions. The interconnection layer has circuits embedded in the insulating material on the device portions. The insulating material has isolating structures raised from top surfaces of the circuits on the device portion, and some of the semiconductor circuit layers form at least one heterojunction.

Abstract: This disclosure provides a data processing method. The method includes: A backup server receives a metadata obtaining command, where the metadata obtaining command is used to obtain file system metadata in a first format, and the command includes an identifier of a to-be-read target directory. The backup server obtains, from a metadata storage area of an archive storage based on the identifier of the target directory, file system metadata that is in a second format and that corresponds to the target directory, converts the file system metadata that is in the second format and that corresponds to the target directory into file system metadata that is in the first format and that corresponds to the target directory, and returns the file system metadata.

Abstract: The present invention relates to an indole carboxamide compound, preparation therefor and use thereof. The indole carboxamide is represented by the following general formula (I). The compound of the present invention is more stable and active and can be used for prophylaxis or treatment of nephropathy, sepsis, arthritis, pulmonary hypertension or tumor.

Abstract: A method for generating a computation flow graph scheduling scheme includes grouping original vertexes in an original computation flow graph, so as to obtain first computation flow graphs; determining the number N of computing units required to process a single batch of computation data in parallel; copying N first computation flow graphs, so as to obtain second computation flow graphs; adding auxiliary vertexes to the second computation flow graphs, so as to obtain third computation flow graphs; constructing integer linear programming according to the third computation flow graphs; and solving the integer linear programming, so as to obtain a scheduling scheme for the third computation flow graphs. The method converts an original computation flow graph into third computation flow graphs and integer linear programming is constructed to obtain a scheduling scheme.

Abstract: Provided are a method and apparatus for translating words in a picture, an electronic device, and a storage medium. The method includes: recognizing words embedded in a target picture to obtain at least one text line, each of which corresponds to one line of words; perform paragraph combination on the at least one text line to obtain at least one text paragraph; translating the at least one text paragraph into at least one target text paragraph in a specified language; and replacing the words in the target picture with the at least one target text paragraph.

Abstract: The present invention relates to the field of inland vessel identification and ranging technology, and discloses a method, system, medium, equipment and terminal for identifying and ranging inland vessels. In the stage of vessel identification, based on the classical YOLO-V4 network model, the MobileNetV1 network is used to replace the feature extraction network CSPDarknet53 of the YOLO-V4 model; In the stage of vessel ranging, a binocular stereo vision ranging model is established, and the FSRCNN is used for super-resolution reconstruction of the original image pairs to enhance the vessel feature information; the ORB algorithm is used to achieve feature detection and matching at the sub-pixel level to obtain the parallax value between image pairs, and the depth information of the vessel target is obtained by triangulation principle and coordinate conversion.

Abstract: The present disclosure describes compositions and methods for treating cancer. Embodiments relate to a cell modified to express one or more molecules at a level that is higher or lower than the level of the one or more molecules expressed by a cell that has not been modified to express the one or more molecules, wherein the one or more molecules comprise Cavin3, ZBED2, and MYC.

Abstract: The present disclosure discloses an electronic table card, a fixed seat of an electronic table card and an electronic table card assembly. The fixed seat includes a base seat and a fixing assembly. The base seat includes a bottom plate and two side plates. The two side plates cooperate with the bottom plate to form a triangular structure, and each of the side plates is provided with a mounting opening that has a shape corresponding to that of the protrusion of the electronic table card and allows the protrusion to probe into the triangular structure. The fixing assembly is configured to be clamped with the clamping slot of the protrusion extending into the triangular structure.

Abstract: A magnetically-isolated wireless charging assembly enabling temporary attachment by magnetism to a device requiring charge by induction includes a housing defining an accommodating space, a plurality of magnetic members disposed within the accommodating space, a wireless charging receiver covering the plurality of magnetic members, and a wireless charging receiver. The wireless charging receiver is disposed on a side of the magnetic shielding member facing the plurality of magnetic members and the magnetic shielding member prevents the magnetic field of the magnetic members extending through or beyond the shielding member.

Abstract: A non-invasive time domain reflection probe calibration method includes: using different volume ratio of ethanol and deionized water mixed solution to calculate a test target's medium weight coefficient and waveguide length of the non-invasive time domain reflection probes; using different concentrations of NaCl solutions to calibrate a waveguide geometric dimensioning of the non-invasive time domain reflection probes; preparing compacted soil samples with known different moisture contents and densities, and calibrating a correlation parameter of compacted soil samples' dielectric constant and conductivity with moisture content and density. The method not only determines the sensitivity of the test target medium of the non-invasive time domain reflection probes, but also obtains the waveguide length and geometric dimensioning of the probe, and realizes an accurate test of moisture content and density of the soil.

Abstract: Disclosed is a method for automatically generating interactive test cases. The method comprises: after a UI of an application program is displayed, traversing all views in a view tree corresponding to the UI of the application program, and recording a path, in the view tree, of each view therein that can be clicked on, so as to obtain a set of path information, in the view tree, of all the views that can be clicked on in the UI; and respectively generating a corresponding test case for each piece of path information in the set: in the test case, according to path information, in the view tree, of a view under test, finding the view in the UI interface of the application program, and triggering a click event therefore, that is, completing a click interaction test on the view. In the present invention, there is no strict requirements for the type and the running environment of an application program.

Abstract: A modular blade connection structure includes a first module, a second module and a structural adhesive module. The first module is provided on an end face thereof with a bonding flange extending into the second module; a gap between the butting surfaces of the first module and the second module is injected with a structural adhesive, which is extruded and cured to form a structural adhesive module; and the thickness of the first module at the starting end of the bonding flange extends towards the inner surface to form a first reinforcement, and the structural adhesive module extends inside the second module in a direction away from the bonding flange to form a second reinforcement. The present disclosure facilitates the control the bonding quality of the double-sided overlapping of the modular blade by means of the bonding flange and the improvement of the fatigue resistance at the assembling position.

Abstract: Waterborne dispersions including crosslinkable multistage polymeric particles useful in coating compositions are provided. The multistage particles have a last-formed layer that includes a diketone functionality that is capable of crosslinking via a dihydrazide component also included in the dispersion. Another embodiment of the waterborne dispersion further includes crosslinkable latex particles having a diketone functionality that are capable of crosslinking with each other and/or the multistage particles via the dihydrazide component. An emulsion polymerization process for forming the multistage particles also is provided. Also provided are coating compositions that contain either embodiment of the waterborne dispersions.

Abstract: Carrier signal generators are provided. The carrier signal generator includes a master processing module and a plurality of slave processing modules. Each slave processing module is used to control a corresponding one of universal power units of the UPS. The slave processing modules output, according to a synchronously received reference signal, control signals to control the universal power units to receive power from the mains or a rechargeable battery. When the mains is normal, each slave processing module synchronously generates a three-phase rectification control signal to rectify and output power from the mains. When the mains is abnormal, each slave processing module generates a first DC-DC control signal independently of the reference signal output by the master processing module, so as to convert and output power from the rechargeable battery. The carrier signal generator has improved compatibility and improved current conversion quality and is low cost.