Patent number: 9242938
Abstract: Disclosed are a glycine reuptake inhibitor and the use thereof. The glycine reuptake inhibitor is a compound of formula I, or isomers, pharmaceutically acceptable salts or solvates thereof, wherein R1 is one or more groups selected from hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, nitro, cyano, amino, hydroxyl, C1-6 haloalkyl, and C1-6 haloalkoxy; R2 is selected from hydrogen, C1-6 alkyl, C1-6 alkoxy, C1-6 haloalkyl, and C1-6 haloalkoxy; and each of R3 and R4 is independently selected from hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, nitro, cyano, amino, hydroxyl, C1-6 haloalkyl, and C1-6 haloalkoxy.
Type:
Grant
Filed:
November 21, 2012
Date of Patent:
January 26, 2016
Assignees:
Beijing Medisan Technology Co., Ltd, Harbin Medisan Pharmaceutical Co., Ltd.
Inventors:
Jinai Liu, Mingxin Wang, Fan Yang, Ailing Wang, Yan Zhu, Jin Cui, Lei Ji