Patents by Inventor Leif Lindholm

Leif Lindholm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7456008
    Abstract: A modified virus including one or more non-native polypeptides, and the use of such viruses in therapy, particularly in the treatment of tumours or other cancerous cells are disclosed. The polypeptides includes one or more framework moieties each containing one or more binding moieties, and is capable of being expressed in the cytoplasm and nucleus of a mammalian host cell in a conformation which is maintained in the absence of a ligand for the binding moieties. The conformation allows the binding moieties subsequently to bind with the ligand, and the polypeptide is capable of transport through the nuclear membrane, wherein the modified virus has an altered tropism conferred by the binding moieties.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: November 25, 2008
    Assignee: Got-A-Gene AB
    Inventors: Leif Lindholm, Anna Karin Nord, Pierre Alain Boulanger
  • Patent number: 6981466
    Abstract: A milk metering apparatus having a metering chamber 7 which is repeatedly filled and emptied many times in the course of milking an animal is provided with a probe 15 which extends down into the metering chamber 7 and which includes a sampling tube as well as conductivity and light absorption sensors. Milk samples can be taken and conductivity and light absorption measurements can be made during each filling and emptying cycle so that data from the sample analysis and the measurements over the whole period of milking can be compared with corresponding data from previous milkings of the same animal thereby providing valuable information for herd management purposes.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: January 3, 2006
    Assignee: Delaval Holding AB
    Inventor: Leif Lindholm
  • Publication number: 20040168644
    Abstract: A milk metering apparatus having a metering chamber 7 which is repeatedly filled and emptied many times in the course of milking an animal is provided with a probe 15 which extends down into the metering chamber 7 and which includes a sampling tube as well as conductivity and light absorption sensors. Milk samples can be taken and conductivity and light absorption measurements can be made during each filling and emptying cycle so that data from the sample analysis and the measurements over the whole period of milking can be compared with corresponding data from previous milkings of the same animal thereby providing valuable information for herd management purposes.
    Type: Application
    Filed: January 26, 2004
    Publication date: September 2, 2004
    Inventor: Leif Lindholm
  • Publication number: 20040132007
    Abstract: The present invention describes a modified virus comprising one or more non-native polypeptides, which polypeptide comprises one or more framework moieties each containing one or more binding moieties, which polypeptide is capable of being expressed in the cytoplasm and nucleus of a mammalian host cell in a conformation which is maintained in the absence of a ligand for said binding moieties, said conformation allowing said binding moieties subsequently to bind with said ligand, and which polypeptide is capable of transport though the nuclear membrane, wherein said modified virus has an altered tropism conferred by said binding moieties and the use of such viruses in therapy, particularly in the treatment of tumours or other cancerous cells.
    Type: Application
    Filed: October 6, 2003
    Publication date: July 8, 2004
    Inventors: Leif Lindholm, Anna Karin Nord, Pierre Alain Boulanger
  • Patent number: 6371046
    Abstract: The present invention relates to a method for automatic separation of foremilk and/or milk not suitable for consumption from the milk line system of a milking plant and an apparatus for carrying out said method. A separating device (44) is arranged at the ends of a milk line (52) and a test milk line (56), said milk lines being parallel. The separating device is designed with a damper means (48) attached to a cup (46). When milk is fed through the outlet (16), the cup (46) is filled up and its weight pivots the separating device from a first position, in which the inlet to a milk line (52) is closed by means of the damper mean, to a second position, in which the milk in cup is poured into a test milk line (56) and the damper means is lifted off the inlet (50|) to the milk line (52).
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: April 16, 2002
    Assignee: De Laval Holding AB
    Inventors: Torbjorn Petterson, Jonas Lundwall, Otto Hellekant, Pernilla Hanssen, Thomas Axelsson, Leif Lindholm, Lars Andersson
  • Patent number: 6189486
    Abstract: An apparatus for and a method of performing an animal-related action regarding at least a part of the body of an animal is proposed. The apparatus includes a cleaning tool (15), adapted to be brought into contact with the part of the body, a support (16, 17) provided to support the cleaning tool (15), and a drive element (18, 24) provided to move the cleaning tool (15) along the contour of the part of the body. A sensor (34) is provided to sense the contact of the cleaning tool (15) and the animal. Furthermore, a processor (36) is provided to determine the position of the part in response to the sensor.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: February 20, 2001
    Assignee: Alfa Laval Agri AB
    Inventor: Leif Lindholm
  • Patent number: 5695991
    Abstract: A complex between a virus the cell binding receptor of which has been inactivated and an antibody, said antibody having the ability to interact with a specific antigen on the surface of a mammalian cell different from the cellular structure which would otherwise mediate binding of the virus to the cell surface and which antigen has the ability to mediate entrance of a virus vector or infectious virus into mammalian cells.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: December 9, 1997
    Assignee: Got-A-Gene AB
    Inventors: Leif Lindholm, Sven Enerback, Orjan Stranneg.ang.rd
  • Patent number: 4497660
    Abstract: In material applications in which besides a high wear resistance also excellent corrosion resistance, strength and toughness are required, conventional hard metal alloys have appeared inadequate. According to the invention a hard metal alloy now exists which fulfils these requirements. It is based on WC-Ni, and the binder phase of nickel is alloyed with low, well adjusted concentrations of above all Cr and Mo.
    Type: Grant
    Filed: March 13, 1984
    Date of Patent: February 5, 1985
    Assignee: Santrade Limited
    Inventor: Leif Lindholm