Patents by Inventor Leland F. Velicer

Leland F. Velicer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6127112
    Abstract: A gene encoding for A antigen precursor, derived from a Avian herpesvirus, is described. The gene is preferably isolated from a Marek's disease herpesvirus virus (MDHV) and is approximately 1.8-1.9 kbp, found on a DNA fragment of about 2.35 kbp in size. The gene can be used as a building block for vaccines, directly as a diagnostic hybridization probe, to facilitate preparation of diagnostic test kits for MDHV by antigen production and subsequent antibody production, and as a potential source of regulatory elements such as signal peptides or promoters for use with other proteins.
    Type: Grant
    Filed: April 13, 1992
    Date of Patent: October 3, 2000
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Leland F. Velicer, Robert J. Isfort, Hsing-Jien Kung, Paul M. Coussens
  • Patent number: 6087127
    Abstract: DNA encoding glycoproteins gD, gI and gE from Marek's disease herpesvirus is described. The DNA is useful for probes to detect the DNA in the herpesvirus, for expression to produce the glycoproteins that can be used for producing the antibodies which specifically recognize the three glycoprotein antigens, and in the case of the latter two genes, for potential insertion sites for foreign genes and as possible sites for gene inactivation to attenuate MDV field isolates for vaccine purposes.
    Type: Grant
    Filed: July 25, 1991
    Date of Patent: July 11, 2000
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Leland F. Velicer, Peter Brunovskis, Paul M. Coussens
  • Patent number: 5976787
    Abstract: DNA encoding glycoproteins gD, gI and gE from Marek's disease herpesvirus is described The DNA is useful for probes to detect the DNA in the herpesvirus, for expression to produce the glycoproteins that can be used for producing the antibodies which specifically recognize the three glycoprotein antigens, and in the case of the latter two genes for potential insertion sites for foreign genes and as possible sites for gene inactivation to attenuate MDV field isolates for vaccine purposes.
    Type: Grant
    Filed: March 24, 1998
    Date of Patent: November 2, 1999
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Leland F. Velicer, Peter Brunovskis, Paul M. Coussens
  • Patent number: 5866697
    Abstract: DNA encoding glycoproteins gD, gI and part of gE from Marek's disease herpesvirus is described. The DNA is useful for probes to detect the DNA in the herpesvirus, for expression to produce the glycoproteins can be used for producing the antibodies which specifically recognize the three glycoprotein antigens, and in the case of the latter two genes, for potential insertion sites for foreign genes. Novel glycoproteins and regulatory sequences are also disclosed.
    Type: Grant
    Filed: January 28, 1992
    Date of Patent: February 2, 1999
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Leland F. Velicer, Peter Brunovskis, Paul M. Coussens
  • Patent number: 5252716
    Abstract: DNA encoding glycoproteins gD, gI and part of gE from Marek's disease herpesvirus is described. The DNA is useful for probes to detect the DNA in the herpesvirus, for expression to produce the glycoproteins can be used for producing the antibodies which specifically recognize the three glycoprotein antigens, and in the case of the latter two genes, for potential insertion sites for foreign genes. Novel glycoproteins and regulatory sequences are also disclosed.
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: October 12, 1993
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Leland F. Velicer, Peter Brunovskis, Paul M. Coussens
  • Patent number: 5252717
    Abstract: DNA encoding glycoproteins gD, gI and part of gE from Marek's disease herpesvirus is described. The DNA is useful for probes to detect the DNA in the herpesvirus, for expression to produce the glycoproteins can be used for producing the antibodies which specifically recognize the three glycoprotein antigens, and in the case of the latter two genes, for potential insertion sites for foreign genes. Novel glycoproteins and regulatory sequences are also disclosed.
    Type: Grant
    Filed: March 9, 1992
    Date of Patent: October 12, 1993
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Leland F. Velicer, Peter Brunovskis, Paul M. Coussens
  • Patent number: 5138033
    Abstract: DNA encoding glycopropteins gD, gI and part of gE from Marek's disease herpesvirus is described. The DNA is useful for probes to detect the DNA in the herpesvirus, for expression to produce the glycoproteins can be used for producing the antibodies which specifically recognize the three glycoprotein antigens, and in the case of the latter two genes, for potential insertion sites for foreign genes. Novel glycoproteins and regulatory sequences are also disclosed.
    Type: Grant
    Filed: August 24, 1990
    Date of Patent: August 11, 1992
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Leland F. Velicer, Peter Brunovskis, Paul M. Coussens