Patents by Inventor Leng-Siew Yeap

Leng-Siew Yeap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLURIPOTENCY ASSOCIATED EPIGENETIC FACTOR
    Publication number: 20110190152
    Abstract: A method for controlling the pluripotent phenotype of a cell comprising modulating the expression or activity of a ESET/SETDB1 polypeptide, or a homologue thereof, within the cell is provided. Pluripotent cells, cultures of such cells and methods for reprogramming somatic cells to a pluripotent phenotype comprising expressing a ESET/SETDB1 polypeptide in the cells, either alone or in combination with other pluripotency factors, are further provided. Methods for identifying modulators of pluripotency and their use in treating cancer or cancer stem cells are also provided.
    Type: Application
    Filed: June 4, 2009
    Publication date: August 4, 2011
    Inventors: Leng-Siew Yeap, Katsuhiko Hayashi, Azim Surani