Abstract: A process for preparing 6-chloro-.alpha.-methylcarbazole-2-acetic acid and esters thereof by the steps of:(a) reacting 6-chloro-1,2,3,4-tetrahydrocarbazole-2-one with a trialkyl-.alpha.-methylphosphonoacetate to yield the corresponding 3,4-dihydro-.alpha.-methylcarbazole-2-acetic acid ester; and(b) aromatizing the reaction product of step (a), prior to or after saponification, to yield, respectively, 6-chloro-.alpha.-methylcarbazole-2-acetic acid or ester, is described. Additionally, there are described 6-chloro-1,2,3,4-tetrahydrocarbazole-2-one useful as an intermediate, and dihydrocarbazoles useful as intermediates and/or as anti-inflammatory and antirheumatic agents.

Abstract: A process for the preparation of 6-chloro-.alpha.-methylcarbazole-2-acetic acid from 6-chloro-.alpha.-hydroxy-.alpha.-methylcarbazole-2-acetic acid and/or 6-chloro-.alpha.-methylene-2-carboxylic acid, is described. The preparation of intermediates, such as, 6-chloro-.alpha.-hydroxy-.alpha.-methylcarbazole-2-acetic acid and lower alkyl carbazole-2-oxalate, inter alia, is also described.

Abstract: A process for the preparation of 6-chloro-.alpha.-methylcarbazole-2-acetic acid from 6-chloro-.alpha.-hydroxy-.alpha.-methylcarbazole-2-acetic acid and/or 6-chloro-.alpha.-methylene-2-carboxylic acid, is described. The preparation of intermediates, such as, 6-chloro-.alpha.-hydroxy-.alpha.-methylcarbazole-2-acetic acid and lower alkyl carbazole-2-oxalate, inter alia, is also described.

Abstract: A process for preparing 6-chloro-.alpha.-methylcarbazole-2-acetic acid and esters thereof by the steps of:(a) reacting 6-chloro-1,2,3,4-tetrahydrocarbazole-2-one with a trialkyl-.alpha.-methylphosphonoacetate to yield the corresponding 3,4-dihydro-.alpha.-methylcarbazole-2-acetic acid ester; and(b) aromatizing the reaction product of step (a), prior to or after saponification, to yield, respectively, 6-chloro-.alpha.-methylcarbazole-2-acetic acid or ester, is described. Additionally, there are described 6-chloro-1,2,3,4-tetrahydrocarbazole-2-one useful as an intermediate, and dihydrocarbazoles useful as intermediates and/or as anti-inflammatory and antirheumatic agents.

Abstract: Dibenzofurans of the formula ##STR1## wherein R, R.sub.1 and R.sub.2 are as hereinafter described, prepared, inter alia, from the correspondingly substituted phenol and haloketocyclohexane are described. The dibenzofurans of the invention are useful anti-inflammatory, analgesic and anti-rheumatic agents.

Abstract: Dibenzofurans of the formula ##STR1## wherein R, R.sub.1 and R.sub.2 are as hereinafter described PREPARED, INTER ALIA, FROM THE CORRESPONDINGLY SUBSTITUTED PHENOL AND HALOKETOCYCLOHEXANE ARE DESCRIBED. The dibenzofurans of the invention are useful antiinflammatory, analgesic and anti-rheumatic agents.

Abstract: 1,2,3,4-Tetrahydrocarbazoles and cyclopenta[b] indoles prepared from the corresponding phenyl hydrazines and corresponding cyclohexanones or cyclopentanones, respectively, are described. The products of the invention are useful anti-inflammatory, analgesic and anti-rheumatic agents.

Abstract: Tricyclic compounds of the formula ##SPC1##Wherein R.sub.1 is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, trifluoromethyl, cyano, carbamoyl, carboxy, lower alkoxy carbonyl, nitro, amino, mono-lower alkylamino, di-lower alkylamino, acyl, acylamido, sulfamoyl, di-lower alkylsulfamoyl, or difluoromethylsulfonyl; R.sub.2 is hydrogen, lower alkyl, amino-lower alkyl, mono-lower alkyl-amino-lower alkyl, or di-lower alkylamino-lower alkyl; n and r are independently 1 or 2; and X is oxygen or sulfur, prepared, inter alia, from the correspondingly substituted phenol or thiophenol and haloketocyclohexane or pentane carboxylic acid ester, are described. The end products are useful as anti-inflammatory and anti-rheumatic agents.