Patents by Inventor Leon W. Terstappen

Leon W. Terstappen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenotypic characterization of the hematopoietic stem cell
    Patent number: 5840580
    Abstract: One or more population of cells enriched for human hematopoietic stem cells is disclosed. HSC in this population of cells are capable of limited self-renewal and are capable of differentiating into all elements of the hematopoietic system. This population of cells has the phenotype of CD34.sup.+ /CD38.sup.- and more preferably CD34.sup.+ /CD38.sup.- /HLA-DR.sup.+. Cells within this population have been found to express CD13, CD33 and CD71. Hematopoietic stem cells can be used in a number of therapies, including autologous transplantation and in gene therapy.
    Type: Grant
    Filed: May 14, 1997
    Date of Patent: November 24, 1998
    Assignee: Becton Dickinson and Company
    Inventors: Leon W. Terstappen, Michael R. Loken, Shiang Huang, Johanna Olweus, Fridtjof Lund-Johansen