Abstract: The present invention relates to novel methods of synthesis and isolation of dendrimer systems. In particular, the present invention is directed to novel dendrimer conjugates with defined and limited numbers of ligand conjugates and high levels of structural uniformity, methods of synthesizing the same, compositions comprising the conjugates, as well systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, pain therapy, etc.)).

Abstract: A cylindrical drum assembly is rotatably mounted transversely on the front of the boom member of a continuous miner. The drum assembly comprises a pair of independently operable drum sections. Each drum section is driven through an input shaft connected to a motor. The drum sections may be connected by a coupler to form a unitary drum assembly which may be operated by only one of the motors. Torque is transmitted from the input shafts to a bevel gear rotatably supported in the drum section. The bevel gear is nonrotatably connected to a sun gear which in turn drives a plurality of planetary gears connected to a cylindrical planetary cage with a bore defining an inner surface. The cage is connected to a cylindrical inner housing on its outer surface and to an output shaft on its inner surface through a cylindrical shear coupler. A puller shaft is provided to remove the output shaft and the shear coupler.

Abstract: A self-propelled continuous mining machine which includes a mobile frame assembly having a material dislodging device, and a conveying system. A dust collecting system is positioned on the mobile frame assembly for inducing a flow of air through a duct system. As material is dislodged from a mine face, the dust collecting system draws airborne dust created by the dislodging device through the duct system and into the collecting system mounted on the mobile frame assembly. The duct system has two sets of vertical walls each connected to and spaced by a horizontal wall with one set of vertical walls fitting channel-like into the other set of vertical walls. The duct assembly has a gasket, seal or other means of preventing airborne dust from escaping through the two sets of vertical walls. The duct assembly is expandable to increase the capacity of the duct system.