Patents by Inventor Leonardo Manzoni

Leonardo Manzoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aza-tanshinone derivatives, process for their preparation and their use in therapy
    Patent number: 10689342
    Abstract: Object of the present invention are new aza-tanshinone derivatives, a method for their preparation and their use in therapy, particularly, but not limited to, as anti-tumor agents and anti-inflammatories. The invention comprises also the pharmaceutical compositions containing them.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: June 23, 2020
    Assignee: UNIVERSITA' DEGLI STUDI DI TRENTO
    Inventors: Alessandro Provenzani, Vito Giuseppe D'Agostino, Natthakan Thongon, Chiara Zucal, Preet Lal, Valentina Adami, Pierfausto Seneci, Leonardo Manzoni, Luciana Marinelli, Ettore Novellino, Marco Fragai, Claudio Luchinat, Linda Cerofolini, Carmelo Fuccio
  • AZA-TANSHINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY
    Publication number: 20190241516
    Abstract: Object of the present invention are new aza-tanshinone derivatives, a method for their preparation and their use in therapy, particularly, but not limited to, as anti-tumor agents and anti-inflammatories. The invention comprises also the pharmaceutical compositions containing them.
    Type: Application
    Filed: June 14, 2017
    Publication date: August 8, 2019
    Inventors: Alessandro PROVENZANI, Vito Giuseppe D'AGOSTINO, Natthakan THONGON, Chiara ZUCAL, Preet LAL, Valentina ADAMI, Pierfausto SENECI, Leonardo MANZONI, Luciana MARINELLI, Ettore NOVELLINO, Marco FRAGAI, Claudio LUCHINAT, Linda CEROFOLINI, Carmelo FUCCIO
  • Integrin targeted synthetic ligands for diagnostic and therapeutic applications
    Patent number: 9409951
    Abstract: The present invention relates to a novel class of diagnostically or therapeutically effective compounds comprising novel aza-bicycloalkane based cyclic peptides, acting as a targeting moiety towards integrin receptors.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: August 9, 2016
    Assignee: BRACCO IMAGING S.P.A.
    Inventors: Luciano Lattuada, Pierfrancesco Morosini, Fulvio Uggeri, Silvio Aime, Enzo Terreno, Daniela Delli Castelli, Carlo Scolastico, Leonardo Manzoni, Daniela Arosio
  • INTEGRIN TARGETED SYNTHETIC LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
    Publication number: 20140178302
    Abstract: The present invention relates to a novel class of diagnostically or therapeutically effective compounds comprising novel aza-bicycloalkane based cyclic peptides, acting as a targeting moiety towards integrin receptors.
    Type: Application
    Filed: January 13, 2014
    Publication date: June 26, 2014
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Luciano LATTUADA, Pierfrancesco Morosini, Fulvio Uggeri, Silvio Aime, Enzo Terreno, Daniela Delli Castelli, Carlo Scolastico, Leonardo Manzoni, Daniela Arosio
  • Integrin targeted synthetic ligands for diagnostic and therapeutic applications
    Patent number: 8636977
    Abstract: The present invention relates to a novel class of diagnostically or therapeutically effective compounds comprising novel aza-bicycloalkane based cyclic peptides, acting as a targeting moiety towards integrin receptors.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: January 28, 2014
    Assignee: Bracco Imaging S.p.A.
    Inventors: Luciano Lattuada, Pierfrancesco Morosini, Fulvio Uggeri, Silvio Aime, Enzo Terreno, Daniela Delli Castelli, Carlo Scolastico, Leonardo Manzoni, Daniela Arosio
  • Integrin Targeted Synthetic Ligands for Diagnostic and Therapeutic Applications
    Publication number: 20080317668
    Abstract: The present invention relates to a novel class of diagnostically or therapeutically effective compounds comprising novel aza-bicycloalkane based cyclic peptides, acting as a targeting moiety towards integrin receptors.
    Type: Application
    Filed: March 3, 2006
    Publication date: December 25, 2008
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Luciano Lattuada, Pierfrancesco Morosini, Fulvio Uggeri, Silvio Aime, Enzo Terreno, Daniela Delli Castelli, Carlo Scolastico, Leonardo Manzoni, Daniela Arosio
  • Peptidomimetic Compounds and Preparation of Biologically Active Derivatives
    Publication number: 20080139461
    Abstract: The invention relates to novel cyclic peptidomimetic compounds containing the sequence RGD for the preparation of appropriately functionalised antagonists of ?v?3 and ?v?5 integrins, and intended, for example, for the treatment of altered angiogenic phenomena or for the preparation of diagnostically useful compounds.
    Type: Application
    Filed: March 3, 2006
    Publication date: June 12, 2008
    Inventors: Carlo Scolastico, Leonardo Manzoni, Daniela Arosio
  • Peptido-mimetic compounds containing rgd sequence useful as integrin inhibitors, and intermediates thereof
    Publication number: 20070037845
    Abstract: The subject of the present invention are cyclic compounds, in particular having azabicycloalkane structures of the general formula (I) a process for their preparation, and their use as intermediates in the synthesis of biologically active peptidomimetic compounds containing the sequence RGD (Arg-Gly-Asp).
    Type: Application
    Filed: July 5, 2004
    Publication date: February 15, 2007
    Applicant: Universita' Degli Studi Di Milano
    Inventors: Carlo Scolastico, Leonardo Manzoni, Matteo Colombo, Marcello Di Giacomo