Abstract: The present disclosure provides a bioprinter spray head assembly and a bioprinter, wherein the spray head assembly is internally provided with a first flow channel and a second flow channel, an outlet of the first flow channel is adjacent to an outlet of the second flow channel, and the outlet of the second flow channel is configured to make a second material sprayed therefrom move towards a first material out of the outlet of the first flow channel, such that the second material sprayed from the outlet of the second flow channel and the first material sprayed from the outlet of the first flow channel are combined together to form a fluid printing unit. The bioprinter spray head assembly can guide the auxiliary materials to wrap the cells for protection, thereby reducing the cell damage caused by the extrusion pressure and the frictional force subjected in the printing process, so as to improve the survival rate of the cells and present a high reliability.

Abstract: The present disclosure relates to a device for printing a lumen tissue construct, a method for using the same, and a 3D bioprinter. The device includes a spray head assembly for printing a biological construct; and a bioprinting platform for supporting a lumen tissue, and for carrying a biological construct printed by the spray head assembly, and for applying the biological construct to an inner surface of the lumen tissue. The device for printing a lumen tissue construct of the present disclosure provides the spray head assembly and the bioprinting platform, and the spray head assembly applies the biological construct onto the inner surface of the lumen tissue by the bioprinting platform, to avoid such problems as recurrence of thrombus and restenosis of a lumen after the lumen tissue has been implanted for a long time, thereby improving the biological reliability of the lumen tissue.

Abstract: The present invention relates to the technical field of a bioprinter, and in particular relates to a bioprinter temperature control system and a bioprinter. The bioprinter temperature control system provided by the present invention, comprises a flow channel temperature control system, for controlling a temperature of a flow channel between an outlet of a bioprinting material container of a bioprinter and a nozzle of the bioprinter, such that the temperature of the flow channel conforms to a desired temperature of a biological printing material. The temperature control system of the present invention can realize the temperature control of the biological printing material, improving the survival rate of the printing material, and ensuring the biological function of the printing material.

Abstract: A device and method for printing lumen tissue constructs and a 3D bioprinter are disclosed. The device has a spray sprayhead assembly and a bioprinting platform. The spray sprayhead assembly prints a biological construct on an inner surface of a lumen tissue by the bioprinting platform. Problems, such as, recurrence of thrombus and restenosis of a lumen after the lumen tissue has been transplanted for a long time, can be avoided. The biological reliability of the lumen tissue can be improved.

Abstract: The present disclosure provides a bioprinter spray head assembly and a bioprinter, wherein the spray head assembly is internally provided with a first flow channel and a second flow channel, an outlet of the first flow channel is adjacent to an outlet of the second flow channel, and the outlet of the second flow channel is configured to make a second material sprayed therefrom move towards a first material out of the outlet of the first flow channel, such that the second material sprayed from the outlet of the second flow channel and the first material sprayed from the outlet of the first flow channel are combined together to form a fluid printing unit. The bioprinter spray head assembly can guide the auxiliary materials to wrap the cells for protection, thereby reducing the cell damage caused by the extrusion pressure and the frictional force subjected in the printing process, so as to improve the survival rate of the cells and present a high reliability.

Abstract: A device and method for printing lumen tissue constructs and a 3D bioprinter are disclosed. The device has a spray sprayhead assembly and a bioprinting platform. The spray sprayhead assembly prints a biological construct on an inner surface of a lumen tissue by the bioprinting platform. Problems, such as, recurrence of thrombus and restenosis of a lumen after the lumen tissue has been transplanted for a long time, can be avoided. The biological reliability of the lumen tissue can be improved.

Abstract: The present disclosure relates to a bioprinter spray head assembly, comprising a mounting block having a passage and a spray head mounted in the passage, wherein a first flow channel is provided in the mounting block, one end of the first flow channel is provided with a port communicating with the passage; the spray head comprises an equal diameter portion away from an outlet of the passage and a reduced diameter portion close to the outlet of the passage, wherein a second flow channel is formed between the reduced diameter portion and the passage, an opening is formed between the reduced diameter portion and the port to communicate the first flow channel and the second flow channel, and the equal diameter portion is configured to occlude the port. The adjustment of the circulation area of the spray head assembly may be achieved by changing the relative positions of the reduced diameter portion and the port, so that the adjustment is convenient and easy to carry out, and there is a favorable implementability.

Abstract: The present disclosure relates to a bioprinter, which comprises a spray head, a connector and a bioprinting material container having a discharge pipe, wherein a first end of the connector is threadedly connected with the discharge pipe, and a second end of the connector is detachably connected with the spray head. The bioprinter is configured such that, a connector is provided between the discharge pipe of the bioprinting material container and the spray head, wherein the first end of the connector is threadedly connected with the discharge pipe, and the second end is detachably disposed on the spray head.

Abstract: The present disclosure relates to a bioprinter spray head assembly and a bioprinter, wherein the bioprinter spray head assembly comprises a spray head and an extension rod spaced from the spray head and disposed adjacent to an outlet of the spray head, wherein an elongated flow channel is provided in the extension rod to guide a fluid printing unit serving as a biological printing material in the flow channel to be orientedly sprayed. The bioprinter spray head assembly is configured such that a fluid print unit serving as a biological printing material is orientedly sprayed through the flow channel by providing an extension rod having an elongated flow channel adjacent to the outlet of the spray head. The elongated flow channel can perform an oriented sequence of the fluid printing unit, so as to reduce the possibility of clogging.

Abstract: The present disclosure relates to a device for printing lumen tissue construct, a method for using the same and 3D bioprinter. Wherein, the device includes a spray head assembly for printing a biological construct; and a bioprinting platform for supporting a lumen tissue, and for carrying a biological construct printed by the spray head assembly, and for applying the biological construct to an inner surface of the lumen tissue. The device for printing lumen tissue construct of the present disclosure provides the spray head assembly and the bioprinting platform, and the spray head assembly applies the biological construct onto the inner surface of the lumen tissue by the bioprinting platform, to avoid such problems as recurrence of thrombus and restenosis of a lumen after the lumen tissue has been implanted for a long time, thereby improving the biological reliability of the lumen tissue.

Abstract: The present invention relates to a device for printing lumen tissue construct, a method for using the same and a 3D bioprinter. Wherein, the device comprises a spray sprayhead assembly and a bioprinting platform, the spray sprayhead assembly prints a biological construct on an inner surface of a lumen tissue by the bioprinting platform. the device for printing lumen tissue construct of the present invention provides the sprayhead assembly and the bioprinting platform, and the sprayhead assembly prints the biological construct on the inner surface of the lumen tissue by the bioprinting platform, thus avoid such problems as recurrence of thrombus and restenosis of a lumen after the lumen tissue has been transplanted for a long time, thereby improving the biological reliability of the lumen tissue.

Abstract: The present disclosure relates to a bioprinter spray head assembly, comprising a mounting block having a passage and a spray head mounted in the passage, wherein a first flow channel is provided in the mounting block, one end of the first flow channel is provided with a port communicating with the passage; the spray head comprises an equal diameter portion away from an outlet of the passage and a reduced diameter portion close to the outlet of the passage, wherein a second flow channel is formed between the reduced diameter portion and the passage, an opening is formed between the reduced diameter portion and the port to communicate the first flow channel and the second flow channel, and the equal diameter portion is configured to occlude the port. The adjustment of the circulation area of the spray head assembly may be achieved by changing the relative positions of the reduced diameter portion and the port, so that the adjustment is convenient and easy to carry out, and there is a favorable implementability.

Abstract: The present invention relates to the technical field of a bioprinter, and in particular relates to a bioprinter temperature control system and a bioprinter. The bioprinter temperature control system provided by the present invention, comprises a flow channel temperature control system, for controlling a temperature of a flow channel between an outlet of a bioprinting material container of a bioprinter and a nozzle of the bioprinter, such that the temperature of the flow channel conforms to a desired temperature of a biological printing material. The temperature control system of the present invention can realize the temperature control of the biological printing material, improving the survival rate of the printing material, and ensuring the biological function of the printing material.

Abstract: The present disclosure relates to a bioprinter spray head assembly and a bioprinter, wherein the bioprinter spray head assembly comprises a spray head and an extension rod spaced from the spray head and disposed adjacent to an outlet of the spray head, wherein an elongated flow channel is provided in the extension rod to guide a fluid printing unit serving as a biological printing material in the flow channel to be orientedly sprayed. The bioprinter spray head assembly is configured such that a fluid print unit serving as a biological printing material is orientedly sprayed through the flow channel by providing an extension rod having an elongated flow channel adjacent to the outlet of the spray head. The elongated flow channel can perform an oriented sequence of the fluid printing unit, so as to reduce the possibility of clogging.