Patents by Inventor Les Jones

Les Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODULATING RSV INFECTION AND IMMUNITY
    Publication number: 20140288267
    Abstract: Compositions and methods are provided for the treatment or prevention of RSV disease by modulating RSV infection and immunity. In particular, amino acid sequences in the RSV G glycoprotein, containing the chemokine motif defined as C-X-X-X-C (or CX3C), are identified that are essential in causing RSV infection and disease. The chemokine motif is biologically active and participates in virus binding to and infection of susceptible cells. The prevention or treatment of RSV infection is achieved by interfering with the motif, such as by administering a vaccine in which the motif is altered or by administration or induction of blocking molecules that inhibit the biological activity of the motif.
    Type: Application
    Filed: April 15, 2014
    Publication date: September 25, 2014
    Applicant: The U.S.A., as represented by the Secretary, Department of Health and Human Service
    Inventors: Ralph A. Tripp, Les Jones, Larry J. Anderson
  • Compositions and methods for modulating RSV infection and immunity
    Patent number: 8778354
    Abstract: Compositions and methods are provided for the treatment or prevention of RSV disease by modulating RSV infection and immunity. In particular, amino acid sequences in the RSV G glycoprotein, containing the chemokine motif defined as C-X-X-X-C (or CX3C), are identified that are essential in causing RSV infection and disease. The chemokine motif is biologically active and participates in virus binding to and infection of susceptible cells. The prevention or treatment of RSV infection is achieved by interfering with the motif, such as by administering a vaccine in which the motif is altered or by administration or induction of blocking molecules that inhibit the biological activity of the motif.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: July 15, 2014
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Ralph A. Tripp, Les Jones, Larry J. Anderson
  • COMPOSITIONS AND METHODS FOR MODULATING RSV INFECTION AND IMMUNITY
    Publication number: 20120258111
    Abstract: Compositions and methods are provided for the treatment or prevention of RSV disease by modulating RSV infection and immunity. In particular, amino acid sequences in the RSV G glycoprotein, containing the chemokine motif defined as C-X-X-X-C (or CX3C), are identified that are essential in causing RSV infection and disease. The chemokine motif is biologically active and participates in virus binding to and infection of susceptible cells. The prevention or treatment of RSV infection is achieved by interfering with the motif, such as by administering a vaccine in which the motif is altered or by administration or induction of blocking molecules that inhibit the biological activity of the motif.
    Type: Application
    Filed: January 25, 2012
    Publication date: October 11, 2012
    Applicants: Services
    Inventors: Ralph A. Tripp, Les Jones, Larry J. Anderson
  • Compositions and methods for modulating RSV infection and immunity
    Patent number: 8173131
    Abstract: Compositions and methods are provided for the treatment or prevention of RSV disease by modulating RSV infection and immunity. In particular, amino acid sequences in the RSV G glycoprotein, containing the chemokine motif defined as C-X-X-X-C (or CX3C), are identified that are essential in causing RSV infection and disease. The chemokine motif is biologically active and participates in virus binding to and infection of susceptible cells. The prevention or treatment of RSV infection is achieved by interfering with the motif, such as by administering a vaccine in which the motif is altered or by administration or induction of blocking molecules that inhibit the biological activity of the motif.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: May 8, 2012
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Ralph A. Tripp, Les Jones, Larry J. Anderson
  • Detection of biomolecules
    Publication number: 20070092870
    Abstract: Compositions, systems and methods for the detection of analytes with labeled nanostructures are provided. In particular, compositions and systems including labeled nanostructures for detecting a biomolecule of interest, and methods of use thereof, are provided.
    Type: Application
    Filed: October 20, 2006
    Publication date: April 26, 2007
    Inventors: Yiping Zhao, Ralph Tripp, Junxue Fu, Les Jones, Rene Alvarez
  • Compositions and methods for modulating RSV infection and immunity
    Publication number: 20060018925
    Abstract: Compositions and methods are provided for the treatment or prevention of RSV disease by modulating RSV infection and immunity. In particular, amino acid sequences in the RSV G glycoprotein, containing the chemokine motif defined as C-X-X-X-C (or CX3C), are identified that are essential in causing RSV infection and disease. The chemokine motif is biologically active and participates in virus binding to and infection of susceptible cells. The prevention or treatment of RSV infection is achieved by interfering with the motif, such as by administering a vaccine in which the motif is altered or by administration or induction of blocking molecules that inhibit the biological activity of the motif.
    Type: Application
    Filed: May 26, 2005
    Publication date: January 26, 2006
    Inventors: Ralph Tripp, Les Jones, Larry Anderson
  • Compositions and methods for modulating RSV infection and immunity
    Publication number: 20040009177
    Abstract: Compositions and methods are provided for the treatment or prevention of RSV disease by modulating RSV infection and immunity. In particular, amino acid sequences in the RSV G glycoprotein, containing the chemokine motif defined as C-X-X-X-C (or CX3C), are identified that are essential in causing RSV infection and disease. The chemokine motif is biologically active and participates in virus binding to and infection of susceptible cells. The prevention or treatment of RSV infection is achieved by interfering with the motif, such as by administering a vaccine in which the motif is altered or by administration or induction of blocking molecules that inhibit the biological activity of the motif.
    Type: Application
    Filed: April 18, 2003
    Publication date: January 15, 2004
    Inventors: Ralph A. Tripp, Les Jones, Larry J. Anderson