Patents by Inventor Lesley Michalowsky

Lesley Michalowsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for fetal DNA detection and allele quantitation
    Publication number: 20030211522
    Abstract: The present invention provides non-invasive methods to distinguish fetal DNA from maternal DNA and thereby detect fetal aneuploidies and alleles. The methods require isolation of fetal DNA from maternal serum and treatment with a reagent that creates primary sequence differences between maternal and fetal DNA that exhibit differential methylation. Various methods including quantitative PCR is used to identify detect fetal aneuploidies and alleles. In one embodiment, the method is useful to identify imprinting genes in subjects, including adults.
    Type: Application
    Filed: January 17, 2003
    Publication date: November 13, 2003
    Inventors: Gregory M. Landes, Lesley Michalowsky, Glenn Miller, William Weber