Patents by Inventor Leslie Ina Gold

Leslie Ina Gold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generation of native recombinant secreted human endoplasmic reticulum chaperones by using their native signal sequences in yeast expression systems
    Patent number: 9796971
    Abstract: A method using yeast as a host for production of human ER chaperone proteins, using endogenous signal peptides of intracellular human proteins that are recognized and correctly processed in the yeast cells to subsequently lead to the secretion of the human proteins. The resultant proteins possessed native amino acid sequence and were biologically active. Moreover, secretion allowed simple one-step purification of native recombinant human proteins with high yields.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: October 24, 2017
    Assignee: UAB BALTYMAS
    Inventors: Evaldas Ciplys, Rimantas Slibinskas, Kestutis Sasnauskas, Marek Michalak, Leslie Ina Gold
  • Generation of Native Recombinant Secreted Human Endoplasmic Reticulum Chaperones by Using Their Native Signal Sequences in Yeast Expression Systems
    Publication number: 20150191713
    Abstract: A method using yeast as a host for production of human ER chaperone proteins, using endogenous signal peptides of intracellular human proteins that are recognized and correctly processed in the yeast cells to subsequently lead to the secretion of the human proteins. The resultant proteins possessed native amino acid sequence and were biologically active. Moreover, secretion allowed simple one-step purification of native recombinant human proteins with high yields.
    Type: Application
    Filed: January 12, 2015
    Publication date: July 9, 2015
    Applicant: UAB BALTYMAS
    Inventors: Evaldas Ciplys, Rimantas Slibinskas, Kestutis Sasnauskas, Marek Michalak, Leslie Ina Gold