Patents by Inventor Leslie Robert Evans

Leslie Robert Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene Expression Technique
    Publication number: 20130244277
    Abstract: The present invention provides a host cell suitable for enhanced production of a protein product of choice characterised in that the host cell is genetically modified to cause over-expression of two or more helper proteins selected from a DnaJ-like protein (such as JEM1), an Hsp70 family protein (such as LHS1) and SIL1, wherein at least one of the over-expressed two or more helper proteins is selected from JEM1, LHS1 and SIL1, and wherein the DnaJ-like protein is not SCJ1.
    Type: Application
    Filed: March 4, 2013
    Publication date: September 19, 2013
    Applicants: UNIVERSITY OF NOTTINGHAM, NOVOZYMES BIOPHARMA DK A/S
    Inventors: Thomas Payne, Darrell Sleep, Christopher John Arthur Finnis, Leslie Robert Evans
  • Method of Controlling O-Linked Glycosylation of Antibodies
    Publication number: 20120059155
    Abstract: A method for producing antibodies in fungal host cells is provided where the produced antibodies has a low degree of glycosylation.
    Type: Application
    Filed: May 7, 2010
    Publication date: March 8, 2012
    Applicant: NOVOZYMES BIOPHARMA DK A/S
    Inventors: Leslie Robert Evans, Miranda Hughes, Joanna Hay, Darrell Sleep, David John Tooth, Neil Dodsworth, Malcolm John Saxton, Joanne Patricia Waters, Steven Athwal
  • Gene Expression Technique
    Publication number: 20110020865
    Abstract: The present invention provides a host cell suitable for enhanced production of a protein product of choice characterised in that the host cell is genetically modified to cause over-expression of two or more helper proteins selected from a DnaJ-like protein (such as JEM1), an Hsp70 family protein (such as LHS1) and SIL1 wherein at least one of the over-expressed two or more helper proteins is selected from JEM1, LHS1 and SIL1, and wherein the DnaJ-like protein is not SCJ1.
    Type: Application
    Filed: June 22, 2006
    Publication date: January 27, 2011
    Applicants: Novozymes Delta Limited, University of Nottigham
    Inventors: Thomas Payne, Darrell Sleep, Christopher John Arthur Finnis, Leslie Robert Evans