Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: The present disclosure relates to a kit comprising: (i) a first part comprising a food bowl assembly including a first bowl having side walls and a base; a second feeding bowl disposed within the first bowl, the second feeding bowl having side walls and a solid base, the inner surface of said side walls and solid base being a closed surface; a separating module adapted to hold an olfactive product, the separating module being arranged to fit between the solid base of the second feeding bowl and the first bowl, and a vent arranged to allow odours from the separating module to exit the food bowl assembly between the first bowl and the side walls of the second feeding bowl so that odours do not pass through the second feeding bowl; and (ii) a second part comprising of a container comprising at least one olfactive product.

Abstract: The present disclosure provides cell lysis buffers and method of use. Cell lysis buffers may comprise an aqueous solution comprising a buffering agent, a detergent, and cyanate or thiocyanate. The cell lysis buffers may be free or substantially free of urea and/or carbonic acid. Such lysis buffers may be used to lyse cells, e.g., in tissues. The cell lysis buffers may be suitable for use with isotachophoresis.

Abstract: Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic channels of a capillary structure. The methods and apparatuses can include providing at least one capillary barrier that positions a meniscus of the first liquid at a fluid-interface region using capillary forces within the capillary structure. Additionally, a path is provided along one of the channels for the second liquid to flow toward the fluid-interface region. Additionally, gas pressure is released, via a gas-outflow port, from the fluid-interface region while flow of the first liquid is arrested. Further, the first liquid and the second liquid contact in the fluid-interface region with the capillary barrier holding the first liquid at the fluid-interface region.

Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: A data-fetching and data-rendering system may, in response to receiving a page display request, construct a static, possibly nested query for retrieving all the data to be rendered for the page and store the query result in a data store. For a future page display request, the system may similarly construct a query and determine whether the query can be resolved from the data store. If not, the system may construct a “diff query” to fetch only the missing data. In some embodiments, in response to a subsequent page update request, the system may retrieve from the server all the data likely to be viewed or updated and render the data changes corresponding to the requested update. The system may then submit the data changes to the server and undo the rendering of the data changes when the server fails to process the data changes.

Abstract: Disclosed herein are diaminopyridine compounds or pharmaceutically acceptable salts thereof having antimalarial activation effect.

Abstract: Embodiments are disclosed for fast data fetching and rendering. In some embodiments, in response to receiving a page display request, a system constructs a static, possibly nested query for retrieving all the data to be rendered for the page and stores the query result in a data store. For a future page display request, the system similarly constructs a query and determines whether the query can be resolved from the data store. If not, the system constructs a “diff query” to fetch only the missing data. In some embodiments, in response to a subsequent page update request, the system retrieves from the server all the data likely to be viewed or updated and renders the data changes corresponding to the requested update. The system then submits the data changes to the server and undoes the rendering of the data changes when the server fails to process the data changes.

Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic channels of a capillary structure. The methods and apparatuses can include providing at least one capillary barrier that positions a meniscus of the first liquid at a fluid-interface region using capillary forces within the capillary structure. Additionally, a path is provided along one of the channels for the second liquid to flow toward the fluid-interface region. Additionally, gas pressure is released, via a gas-outflow port, from the fluid-interface region while flow of the first liquid is arrested. Further, the first liquid and the second liquid contact in the fluid-interface region with the capillary barrier holding the first liquid at the fluid-interface region.

Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic channels of a capillary structure. The methods and apparatuses can include providing at least one capillary barrier that positions a meniscus of the first liquid at a fluid-interface region using capillary forces within the capillary structure. Additionally, a path is provided along one of the channels for the second liquid to flow toward the fluid-interface region. Additionally, gas pressure is released, via a gas-outflow port, from the fluid-interface region while flow of the first liquid is arrested. Further, the first liquid and the second liquid contact in the fluid-interface region with the capillary barrier holding the first liquid at the fluid-interface region.

Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: Embodiments are disclosed for fast data fetching and rendering. In some embodiments, in response to receiving a page display request, a system constructs a static, possibly nested query for retrieving all the data to be rendered for the page and stores the query result in a data store. For a future page display request, the system similarly constructs a query and determines whether the query can be resolved from the data store. If not, the system constructs a “diff query” to fetch only the missing data. In some embodiments, in response to a subsequent page update request, the system retrieves from the server all the data likely to be viewed or updated and renders the data changes corresponding to the requested update. The system then submits the data changes to the server and undoes the rendering of the data changes when the server fails to process the data changes.

Abstract: Embodiments are disclosed for fast data fetching and rendering. In some embodiments, in response to receiving a page display request, a system constructs a static, possibly nested query for retrieving all the data to be rendered for the page and stores the query result in a data store. For a future page display request, the system similarly constructs a query and determines whether the query can be resolved from the data store. If not, the system constructs a “diff query” to fetch only the missing data. In some embodiments, in response to a subsequent page update request, the system retrieves from the server all the data likely to be viewed or updated and renders the data changes corresponding to the requested update. The system then submits the data changes to the server and undoes the rendering of the data changes when the server fails to process the data changes.

Abstract: Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic channels of a capillary structure. The methods and apparatuses can include providing at least one capillary barrier that positions a meniscus of the first liquid at a fluid-interface region using capillary forces within the capillary structure. Additionally, a path is provided along one of the channels for the second liquid to flow toward the fluid-interface region. Additionally, gas pressure is released, via a gas-outflow port, from the fluid-interface region while flow of the first liquid is arrested. Further, the first liquid and the second liquid contact in the fluid-interface region with the capillary barrier holding the first liquid at the fluid-interface region.