Patents by Inventor Lewis G. Scharpf, Jr.

Lewis G. Scharpf, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8273381
    Abstract: A composition, system and method for modifying an olfactory response to an odorant is disclosed. In some embodiments, the composition includes crystalline metal nanoparticles dispersed in an aqueous medium. The composition is applied to olfactory tissues using a suitable applicator or dispenser. The metal nanoparticles are believed to interact with a G-protein coupled to receptor located in the cilia to moderate (enhance or reduce) sensitivity or ability to smell particular odorants. In accordance with an embodiment of the invention, the composition includes one or more odorants.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: September 25, 2012
    Assignee: Auburn University
    Inventors: Vitaly J. Vodyanoy, Lewis G. Scharpf, Jr., Alexandre Samoylov, Nilmini Viswaprakash, Ludmila Petrovna Globa, Edward E. Morrison
  • Patent number: 6913906
    Abstract: A modified thaumatin protein and an antibody thereto are provided. Further, nucleic acid sequences and vectors capable of expressing thaumatin or monellin are provided.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: July 5, 2005
    Inventors: Paul L. Bolen, Paul L. Cihak, Lewis G. Scharpf, Jr., Kevin P. Miller, Nicolas Kossiakoff, Regina D. Hawn
  • Patent number: 6844178
    Abstract: The present invention provides kPGE and derivative polypeptides which are capable of being produced by genetic recombination and used to produce EMCs. This invention further provides nucleic acid sequences encoding kPGE and derivative polypeptides which can be used to create recombinant host cells that express kPGE and derivative polypeptides. A further subject of the present of invention is a fusion polypeptide called polyHis-enterokinase which increases expression of esterases and lipases when fused to the N-terminal of the esterase or lipase. This invention also provides a method for treating animals with an esterase or lipase deficiency by administering rkPGE to the animal in a therapeutically effective amount.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: January 18, 2005
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Paul L. Bolen, Paul L. Cihak, Lewis G. Scharpf, Jr.
  • Patent number: 6582948
    Abstract: The present invention provides kPGE and derivative polypeptides which are capable of being produced by genetic recombination and used to produce EMCs. This invention further provides nucleic acid sequences encoding kPGE and derivative polypeptides which can be used to create recombinant host cells that express kPGE and derivative polypeptides. A further subject of the present of invention is a fusion polypeptide called polyHis-enterokinase which increases expression of esterases and lipases when fused to the N-terminal of the esterase or lipase. This invention also provides a method for treating animals with an esterase or lipase deficiency by administering rkPGE to the animal in a therapeutically effective amount.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: June 24, 2003
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Paul L. Bolen, Paul L. Cihak, Lewis G. Scharpf, Jr.
  • Patent number: 6420527
    Abstract: Flavor active proteins and methods for their manufacture and use are provided. The proteins are modified versions of the thaumatin and monellin proteins. Also provided are the cDNA sequences encoding these modified proteins.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: July 16, 2002
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Paul L. Bolen, Paul L. Cihak, Lewis G. Scharpf, Jr., Kevin P. Miller, Nicolas Kossiakoff, Regina D. Hawn
  • Patent number: 6375947
    Abstract: The present invention provides kPGE and derivative polypeptides which are capable of being produced by genetic recombination and used to produce EMCs. This invention further provides nucleic acid sequences encoding kPGE and derivative polypeptides which can be used to create recombinant host cells that express kPGE and derivative polypeptides. A further subject of the present of invention is a fusion polypeptide called polyHis-enterokinase which increases expression of esterases and lipases when fused to the N-terminal of the esterase or lipase. This invention also provides a method for treating animals with an esterase or lipase deficiency by administering rkPGE to the animal in a therapeutically effective amount.
    Type: Grant
    Filed: November 5, 1998
    Date of Patent: April 23, 2002
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Paul L. Bolen, Paul L. Cihak, Lewis G. Scharpf, Jr.
  • Patent number: 6001410
    Abstract: Described is the use of a recombinant single-strand monellin taken alone or further together with sclareolide and/or succinic acid for enhancing the alcoholic impact of a fruit liqueur beverage.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: December 14, 1999
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Paul L. Bolen, Nicholas Kossiakoff, Regina D. Hawn, Lewis G. Scharpf, Jr.
  • Patent number: 5577668
    Abstract: A toroidal manifold sparger having a hollow toroid member with an upper portion and a lower portion and having a plurality of first openings substantially evenly spaced along the lower portion thereof and all oriented perpendicular to the upper portion in a first and vertically downward direction, a plurality of second openings substantially evenly spaced along the lower portion of the toroid member and all oriented in a second direction, the first openings and the second openings being spaced apart from each other, each of the openings having a trajectory such that the trajectory of all of the first openings is parallel to each other and in a downward direction, and the second openings having a trajectory that radially inwardly converges in a downward direction, the first and second openings being the only openings in the lower portion, the toroid member being suspended from the upper portion.
    Type: Grant
    Filed: January 18, 1995
    Date of Patent: November 26, 1996
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Chwan-Kong King, Chee-Teck Tan, Lewis G. Scharpf, Jr., David P. O'Chat, Marvin Schulman
  • Patent number: 5525367
    Abstract: An encapsulated flavoring and coloring agent is made by spray chilling.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: June 11, 1996
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Chwan-Kong King, Chee-Teck Tan, Lewis G. Scharpf, Jr., David P. O'Chat, Marvin Schulman
  • Patent number: 5476675
    Abstract: A process is disclosed for preparing a substantially dry edible flavor fiber product by admixing water, a powdered flavor, a binder and fiber together and extruding the resulting mixture. The process can be carried out by first admixing a powdered flavor material with a fiber to form a flavor-fiber and mixture, then the flavor-fiber mixture is introduced into an extruder where water is simultaneously introduced and the resulting composition, containing water, fiber and flavor is extruded to form a product. The flavor fiber product can be an instant beverage, such as chocolate.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: December 19, 1995
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Wen C. Lou, Chee-Teck Tan, Lewis G. Scharpf, Jr., Joseph Panarisi
  • Patent number: 5417153
    Abstract: A toroidal sparger is disclosed for use in a fluidized spray chilling system for the production of encapsulated flavoring and coloring agents.
    Type: Grant
    Filed: August 9, 1993
    Date of Patent: May 23, 1995
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Chwan-Kong King, Chee-Teck Tan, Lewis G. Scharpf, Jr., David P. O'Chat, Marvin Schulman