Abstract: A filling and covering machine for centrifuge tubes with tethered caps includes a conveying device, a cap-flapping device, a filling device, and a cap-pressing device. The cap-flapping device has an upper planar surface and a cap-guiding member having a starting end portion, an ending end portion that is opposite to the starting end portion, and a guiding surface extending from the starting end portion to the ending end portion, and cooperates with the upper planar surface to define an included angle therebetween decreasing gradually from the starting end portion to the ending end portion to guide a cap of each of the centrifuge tubes with tethered caps toward a tube body thereof.

Abstract: A message addressed to a user is received. A first model is applied to the message to produce a first output indicative of whether the message is representative of a non-malicious message. The first model is trained using past messages that have been verified as non-malicious messages. It is determined, based on the first output, that the message is potentially a malicious message. Responsive to determining that the message is potentially a malicious email based on the first output, apply a second model to the message to produce a second output indicative of whether the message is representative of a given type of attack. The second model is one of a plurality of models. At least one model included in the plurality of models is associated with characterizing a goal of the malicious message. An action is performed with respect to the message based on the second output.

Abstract: The present disclosure provides engineered WNT agonists and methods of treating gastrointestinal disorders with modulators of the WNT signaling pathway.

Abstract: The present invention provides anti-LRP5/6 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for treating diseases and disorders associated with Wnt pathway signaling.

Abstract: The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.

Abstract: Conventional email filtering services are not suitable for recognizing sophisticated malicious emails, and therefore may allow sophisticated malicious emails to reach inboxes by mistake. Introduced here are threat detection platforms designed to take an integrative approach to detecting security threats. For example, after receiving input indicative of an approval from an individual to access past email received by employees of an enterprise, a threat detection platform can download past emails to build a machine learning (ML) model that understands the norms of communication with internal contacts (e.g., other employees) and/or external contacts (e.g., vendors). By applying the ML model to incoming email, the threat detection platform can identify security threats in real time in a targeted manner.

Abstract: The present disclosure provides tissue-specific Wnt signal enhancing molecules, and related methods of using these molecules to increase Wnt signaling in targeted tissues.

Abstract: Introduced here are computer programs and computer-implemented techniques for discovering malicious emails and then remediating the threat posed by those malicious emails in an automated manner. A threat detection platform may monitor a mailbox to which employees of an enterprise are able to forward emails deemed to be suspicious for analysis. This mailbox may be referred to as an “abuse mailbox” or “phishing mailbox.” The threat detection platform can examine emails contained in the abuse mailbox and then determine whether any of those emails represent threats to the security of the enterprise. For example, the threat detection platform may classify each email contained in the abuse mailbox as being malicious or non-malicious. Thereafter, the threat detection platform may determine what remediation actions, if any, are appropriate for addressing the threat posed by those emails determined to be malicious.

Abstract: A semiconductor device comprises a fin structure disposed over a substrate; a gate structure disposed over part of the fin structure; a source/drain structure, which includes part of the fin structure not covered by the gate structure; an interlayer dielectric layer formed over the fin structure, the gate structure, and the source/drain structure; a contact hole formed in the interlayer dielectric layer; and a contact material disposed in the contact hole. The fin structure extends in a first direction and includes an upper layer, wherein a part of the upper layer is exposed from an isolation insulating layer. The gate structure extends in a second direction perpendicular to the first direction. The contact material includes a silicon phosphide layer and a metal layer.

Abstract: A mobile terminal, includes a housing, and a middle frame and a display that are disposed in the housing. The display is coupled to the middle frame. An accommodation space is formed between the display and the middle frame. In addition, the mobile terminal further includes a first magnet and a second magnet, and a part of the first magnet and a part of the second magnet are disposed in the accommodation space. The first magnet is disposed on a back facet of the display, the second magnet is disposed on the middle frame, and the first magnet and the second magnet are disposed face to face.

Abstract: A double patterning method of manufacturing select gates and word lines is provided in the present invention, including forming first string patterns composed of word line patterns and select gate patterns on a target layer, forming a conformal spacer layer on first string patterns, wherein the spacer layer forms trenches between first string patterns, forming a fill layer filling up the trenches on the spacer layer, removing fill layer outside of the trenches, so that fill layer in the trenches forms second string patterns, wherein the second string patterns and the first string patterns are spaced apart, removing exposed spacer layer, so that the first string patterns and the second string patterns constitute target patterns spaced apart from each other on the target layer, and performing an etching process using those target patterns as a mask to remove exposed target layer, so as to form word lines and select gates.

Abstract: Semiconductor device structures having metal gate structures with tunable work function values are provided. In one example, a first gate structure and a second gate structure formed on a substrate, wherein the first gate structure includes a first work function metal having a first material, and the second gate structure includes a second work function metal having a second material, the first material being different from the second material, wherein the first gate structure further includes a gate dielectric layer, a self-protective layer having metal phosphate, and the first work function metal on the self-protective layer.

Abstract: Bands for wearable devices include multiple band retainers used to maintain engagement between an assembly (e.g., a pair) of bands. Some band retainers may be permanently affixed with the band at a certain location of the band, while other band retainers can be removable. The removable band retainers can be moved to different locations of the band, thus allowing the band retainer to retain another band at different locations. As a result, the assembly of bands can be used with different users, and in particular, users with different wrist sizes. Moreover, using multiple band retainers can provide an engagement force between the bands to withstand higher-impact events, such as swimming and diving. Additionally, bands and band retainers may include one or more liquid-resistant and corrosion-resistant materials.

Abstract: A method for designing a multi-objective primer pair is disclosed. The method includes inputting a DNA template fragment, a length of a forward primer, a length of a reverse primer, at least two objectives and optimal values for each of the at least two objectives to a computer system; generating, by the computer system, a plurality of primer pairs according to the DNA template fragment, the length of the forward primer and the length of the reverse primer; and calculating, by the computer system, numerical values of the at least two objectives of each of the plurality of primer pairs and inputting the numerical values of the at least two objectives of each of the plurality of primer pairs to a Pareto Chart tool to obtain at least one primer pair, and taking the primer pair as an optimal solution of the DNA template fragment.

Abstract: A lighting structure includes a surface cover plate, a lighting module, a light adjustment layer, an optical adhesive layer and an electronic paper display module. The surface cover plate has a visible area and a black bezel. The lighting module has a light guide plate and point light sources. The light adjustment layer has an optical thinning region and a frame-shaped adhesive. The optical thinning region is less than the light guide plate in refractive index. The surface cover plate and the lighting module are adhered by the frame-shaped adhesive. The optical thinning region is disposed on an upper surface of the light guide plate. The optical adhesive layer has a refractive index equal to or greater than a refractive index of the light guide plate. The electronic paper display module is disposed under the lighting module.

Abstract: A method for designing a multi-objective primer pair is disclosed. The method includes inputting a DNA template fragment, a length of a forward primer, a length of a reverse primer, at least two objectives and optimal values for each of the at least two objectives to a computer system; generating, by the computer system, a plurality of primer pairs according to the DNA template fragment, the length of the forward primer and the length of the reverse primer; and calculating, by the computer system, numerical values of the at least two objectives of each of the plurality of primer pairs and inputting the numerical values of the at least two objectives of each of the plurality of primer pairs to a Pareto Chart tool to obtain at least one primer pair, and taking the primer pair as an optimal solution of the DNA template fragment.

Abstract: The invention discloses a test circuit, a test method and an audio codec for testing a microphone module that includes a first microphone and a second microphone. The first microphone outputs the first data, and the second microphone outputs the second data. The test circuit includes a comparison circuit, a counter, and a decision circuit. The comparison circuit is configured to compare the first data with the second data and generate a comparison result. The counter is coupled to the comparison circuit and configured to generate a count value based on the comparison result. The decision circuit is coupled to the counter and configured to indicate, based on the count value and a threshold value, whether the microphone module has an error.

Abstract: The invention provides a switch device including a shell, an operating member, a spring, a movable conductor, a first pin, a second pin, two resistors, and two connecting conductors. The operating member is partially exposed out of the shell, and the movable conductor is displaced when the operating member is operated. One side of the shell is provided with the first pin and the spring, another side is provided with the second pin. The resistors are connected with the second pin and have different resistance values. The connecting conductors are arranged between the two pins. The first pin contacts with the movable conductor. The connecting conductors without disposal of any crossover part therebetween and respectively connected with the resistors. The connecting conductors are arranged at intervals along a displacement path of the movable conductor which contacted one connecting conductor before and after displacement and forming two conductive paths.

Abstract: A protection structure includes a substrate, a signal wire pattern, a protective ring and micro-blocks. The substrate has a touch sensing pattern including sensing strings. The signal wire pattern has conductive wires. Each conductive wire electrically connects one of the sensing strings to a signal processor. The protective ring is formed at a peripheral zone of the substrate and around the touch sensing pattern. The micro-blocks are disposed in the protective ring and have electric conductivity. A gap is disposed between every adjacent two of the micro-blocks for insulation.

Abstract: The invention discloses a test circuit, a test method and an audio codec for testing a microphone module that includes a first microphone and a second microphone. The first microphone outputs the first data, and the second microphone outputs the second data. The test circuit includes a comparison circuit, a counter, and a decision circuit. The comparison circuit is configured to compare the first data with the second data and generate a comparison result. The counter is coupled to the comparison circuit and configured to generate a count value based on the comparison result. The decision circuit is coupled to the counter and configured to indicate, based on the count value and a threshold value, whether the microphone module has an error.