Abstract: A system or computer usable program product for representing a piece of a road as a first ordered series of line segments connected in an end-to-end fashion; representing the piece of the road as a second ordered series of line segments connected in an end-to-end fashion; for each given pair of two consecutive points of the second ordered series of points, determining a corresponding plurality of in-between points from the first ordered series of points; for each given line segment of the second ordered series of line segments, determining a first traffic characteristic value corresponding to the given line segment and a portion of the piece of the road which the given line segment represents; and presenting a visual representation of the piece of the road.

Abstract: A method for mapping infrastructure layout between non-corresponding datasets including accessing from a memory a set of long links with points that trace the curvature of a set of linestrings, accessing from the memory a set of short links that are short enough for analytical purposes wherein each short link represents a straight line, and from the set of long links and the set of short links, using a processor to create a set of hybrid links for storage in the memory, each hybrid link corresponding to one short link for analytic purposes, a plurality of the hybrid links including at least one of the points for tracing the curvature of the set of linestrings.

Abstract: A method for mapping infrastructure layout between non-corresponding datasets including accessing from a memory a set of long links with points that trace the curvature of a set of linestrings, accessing from the memory a set of short links that are short enough for analytical purposes wherein each short link represents a straight line, and from the set of long links and the set of short links, using a processor to create a set of hybrid links for storage in the memory, each hybrid link corresponding to one short link for analytic purposes, a plurality of the hybrid links including at least one of the points for tracing the curvature of the set of linestrings.

Abstract: A system or computer usable program product for representing a piece of a road as a first ordered series of line segments connected in an end-to-end fashion; representing the piece of the road as a second ordered series of line segments connected in an end-to-end fashion; for each given pair of two consecutive points of the second ordered series of points, determining a corresponding plurality of in-between points from the first ordered series of points; for each given line segment of the second ordered series of line segments, determining a first traffic characteristic value corresponding to the given line segment and a portion of the piece of the road which the given line segment represents; and presenting a visual representation of the piece of the road.

Abstract: A system or computer usable program product for mapping infrastructure layout between non-corresponding datasets including accessing from a memory a set of long links with points that trace the curvature of a set of linestrings, accessing from the memory a set of short links that are short enough for analytical purposes wherein each short link represents a straight line, and from the set of long links and the set of short links, using a processor to create a set of hybrid links for storage in the memory, each hybrid link corresponding to one short link for analytic purposes, a plurality of the hybrid links including at least one of the points for tracing the curvature of the set of linestrings.

Abstract: Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) inhibits cell growth and promotes apoptosis by sequestering free Insulin-like Growth Factor (IGF), and also demonstrates IGF-independent, pro-apoptotic, anti-proliferative effects on prostate cancer cells. Prostate tumor size was significantly attenuated in transgenic mice over-expressing IGFBP-3 compared with wild-type mice. In addition, a marked reduction in late-stage tumor growth was apparent in transgenic mice over expressing mutant-IGFBP-3 indicating that the IGF-independent effects of IGFBP-3 are related to inhibiting tumor progression.

Abstract: A method of identifying compounds capable of modulating trans-glutaminase (TG) kinase activity is described. The method involves adding a test compound to a mixture of TG and a suitable TG kinase substrate, incubating the mixture under conditions promoting TG kinase activity, and determining if the test compound activates or modulates TG kinase activity as indicated by greater than expected TG-mediated phosphorylation of the TG kinase substrate or if the test compound inhibits TG kinase activity as indicated by lower than expected TG-mediated phosphorylation of the TG kinase substrate as compared to a control comprising TG and a suitable TG kinase substrate incubated under conditions promoting TG kinase activity.