Abstract: A method and apparatus for finishing a surface of a metal component made by additive manufacturing are provided. The method comprises: containing the component 41 in a fluid 43 that comprises abrasive particles 48; and generating pressure fluctuations that produce acoustic cavitation in the fluid by applying ultrasonic vibration into the fluid by an ultrasonic horn 45, thereby removing material from the surface of the component by a combination of cavitation bubble collapse on the surface and the striking of the surface by abrasive particles 48 accelerated by cavitation bubble collapse.

Abstract: A device having a memory configured to store information indicating debounce times for the device's switches and having circuits configured to determine whether the switches are depressed and closed based on the debounce times. The debounce times are updated based on the age of the device and/or switch usage. The method for debouncing may be performed by a computer having computer-readable media directed to adjusting the debounce times based on the age of the device containing the switches.

Abstract: The present invention relates to an antigen-binding protein, preferably a monoclonal antibody, against annexin A2 (ANXA2), comprising (i) a heavy chain variable domain comprising a VHCDR1 of sequence GYSITSGYSWH, a VHCDR2 of sequence YIHYSGSTKYNPSLKS and a VHCDR3 of sequence GSNYGFDY; and (ii) a light chain variable domain comprising a VLCDR1 of sequence KSSQSLLYSNDQKNYLA, a VLCDR2 of sequence WASIRES, and a VLCDR3 of sequence QQYYIYPLT. Also provided is an ANXA2 binding protein comprising (i) a heavy chain variable domain comprising a VHCDR1 of sequence VYSITSGYSWH; a VHCDR2 of sequence YIHYSGSTKYNPSLKS, and a VHCDR3 of sequence GTDNAVDY; and (ii) a light chain variable domain comprising a VLCDR1 of sequence KSSQSLLYSSNQKNYLA, a VLCDR2 of sequence WASSRES, and a VLCDR3 of sequence QQYYIYPLT. The antibodies preferably bind to an N-linked glycan on ANXA2, and are internalised upon binding. They may be conjugated with cytotoxins and may be used in the treatment or detection of cancer.

Abstract: Most computer operating systems are able to automatically configure the coupled computer peripheral audio device for use with the computer operating system without the need for installation of a specific driver. However, when these computer peripheral audio devices are detected by the computing system, a generic audio device control configuration is often assigned to them and whatever customised settings previously configured by the user will be lost and replaced with a new set of unfamiliar setting. This poses much inconvenience and hassle to gainers when they use a different computing system or machine. Described according to an embodiment of the invention is a headset device and a device profile management method, operating on a computing cloud, comprising steps for receiving client data provided by a computing system detecting coupling of an audio device thereto and for retrieving configuration data corresponding to the client data for use in configuring the audio device by the computing system.

Abstract: According to various embodiments, an energy monitoring method may be provided. The energy monitoring method may include: determining internal energy information indicating a charge state of an internal battery of a computing device; wirelessly receiving external energy information indicating a charge state of an external battery for the computing device; determining a combined energy information indicating a combined charge state of the internal battery and external battery based on the internal energy information and based on the external energy information; and providing a notification to a user of the computing device based on the combined energy information.

Abstract: A mouse for communication with a processor-based device. The mouse may include a housing having a base surface. The base surface may be configured to face a tracking surface on which the mouse may be placed on. The mouse may further include a plurality of mouse foot protrusions projecting from the base surface. A distal end of at least one of the plurality of mouse foot protrusions may be configured to contact the tracking surface on which the mouse may be placed on and the distal end may include a first color. An intermediate portion of the at least one of the plurality of mouse foot protrusions between the distal end of the at least one of the plurality of mouse foot protrusions and the base surface may include a second color, which may be different from the first color.

Abstract: This invention proposes an inductor's electromagnetic balance improvement method which equips protective box inside magnet ring with an arc-shaped shield. It can block out electromagnetism of magnet ring from all angles to reduce remanence, improve inductor's electromagnetic balance, and shorten the gap between action current of fire wire and that of naught wire. In this way, product yield rate can be increased.

Abstract: The present disclosure relates to the field of pharmaceutical synthesis, and more particularly, relates to a monocyclic ?-lactam-siderophore conjugate as well as a method for synthesizing same and its use in the treatment of bacterial infectious diseases. Provided are a monocyclic ?-lactam-siderophore conjugate represented by formula (I) as described herein, an optical isomer thereof or a pharmaceutically acceptable salt thereof, and a method for synthesizing same, and a use thereof in treating bacterial infectious diseases.

Abstract: The present disclosure relates to the field of pharmaceutical synthesis, and more particularly, relates to a monocyclic ?-lactam-siderophore conjugate as well as a method for synthesizing same and its use in the treatment of bacterial infectious diseases. Provided are a monocyclic ?-lactam-siderophore conjugate represented by formula (I) as described herein, an optical isomer thereof or a pharmaceutically acceptable salt thereof, and a method for synthesizing same, and a use thereof in treating bacterial infectious diseases.

Abstract: An electronic device and a heat-dissipation device for an electronic device are provided. The heat-dissipation device comprises an airflow channel; an airflow source located in the airflow channel; a plurality of elongated heat-dissipation fins arranged in the airflow channel; and a plurality of heat-dissipation flow-guiding devices arranged in the airflow channel and between the airflow source and the plurality of elongated heat-dissipation fins, wherein the plurality of heat-dissipation flow-guiding devices include a first heat-dissipation flow-guiding device in a central position of the airflow channel and a second heat-dissipation flow-guiding device on two sides of the airflow channel, and a longitudinal distance between the first heat-dissipation flow-guiding device and the airflow source is less than the distance between the second heat-dissipation flow-guiding device and the airflow source.

Abstract: There is disclosed a method and apparatus for finishing an internal channel of a component. The method comprises installing the component in a flow circuit which is configured to drive a fluid flow through the internal channel and controlling the fluid flow through the internal channel so that cavitation bubbles are continuously generated by a hydrodynamic effect to erode the internal channel by implosion of the cavitation bubbles. The fluid flow may comprise abrasive media which may abrade the internal channel.

Abstract: According to various embodiments, a display device may be provided. The display device may include: a receiver configured to receive user data based on an electroencephalography measurement; at least one light source; and a controller configured to control the at least one light source based on the user data.

Abstract: A package for contact lenses is disclosed. The package may include a body defining an inner volume and a cover extending over an opening when being closed. The package may also include at least one removable section connected between the cover and the body such that after its removal or in its absence the lid portion would be able to open and expose the inner volume of the body. The package can be reclosed by fitting at least one tab into a corresponding groove. A package with at least one attaching element for resealing the inner volume is also disclosed.

Abstract: A method, a computer readable medium, and an apparatus for providing haptic feedback through a plurality of haptic devices are provided. The apparatus may receive a multi-channel audio stream. The apparatus may split the multi-channel audio stream into a plurality of audio channels. For each haptic signal of a plurality of haptic signals, the apparatus may generate the haptic signal based on one or more audio channels of the plurality of audio channels. For each haptic signal of the plurality of haptic signals, the apparatus may transmit the haptic signal to a corresponding haptic device of the plurality of haptic devices to produce the haptic feedback.

Abstract: The present disclosure relates to the field of pharmaceutical synthesis, and more particularly, relates to a monocyclic ?-lactam-siderophore conjugate as well as a method for synthesizing same and its use in the treatment of bacterial infectious diseases. Provided are a monocyclic ?-lactam-siderophore conjugate represented by formula (I) as described herein, an optical isomer thereof or a pharmaceutically acceptable salt thereof, and a method for synthesizing same, and a use thereof in treating bacterial infectious diseases.

Abstract: The present invention relates to an antigen-binding protein, preferably a monoclonal antibody, against annexin A2 (ANXA2), comprising (i) a heavy chain variable domain comprising a VHCDR1 of sequence GYSITSGYSWH, a VHCDR2 of sequence YIHYSGSTKYNPSLKS and a VHCDR3 of sequence GSNYGFDY; and (ii) a light chain variable domain comprising a VLCDR1 of sequence KSSQSLLYSNDQKNYLA, a VLCDR2 of sequence WASIRES, and a VLCDR3 of sequence QQYYIYPLT. Also provided is an ANXA2 binding protein comprising (i) a heavy chain variable domain comprising a VHCDR1 of sequence VYSITSGYSWH; a VHCDR2 of sequence YIHYSGSTKYNPSLKS, and a VHCDR3 of sequence GTDNAVDY; and (ii) a light chain variable domain comprising a VLCDR1 of sequence KSSQSLLYSSNQKNYLA, a VLCDR2 of sequence WASSRES, and a VLCDR3 of sequence QQYYIYPLT. The antibodies preferably bind to an N-linked glycan on ANXA2, and are internalised upon binding. They may be conjugated with cytotoxins and may be used in the treatment or detection of cancer.

Abstract: According to various embodiments, a device may be provided. The device may include: a switch; a memory configured to store information indicating a debounce time; a switch closed determination circuit configured to determine whether the switch is depressed based on the debounce time; and an age compensation circuit configured to update the debounce time based on an age of the device.