Patents by Inventor Lianne Smith

Lianne Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES
    Publication number: 20160106772
    Abstract: Materials, formulations, production methods, and methods for delivery of CFTR mRNA for induction of CFTR expression, including in the mammalian lung are provided. The present invention is particularly useful for treating cystic fibrosis.
    Type: Application
    Filed: October 6, 2015
    Publication date: April 21, 2016
    Inventors: Michael Heartlein, Braydon Charles Guild, Frank DeRosa, Carsten Rudolph, Christian Plank, Lianne Smith
  • CFTR mRNA compositions and related methods and uses
    Patent number: 9181321
    Abstract: Materials, formulations, production methods, and methods for delivery of CFTR mRNA for induction of CFTR expression, including in the mammalian lung are provided. The present invention is particularly useful for treating cystic fibrosis.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: November 10, 2015
    Assignees: Shire Human Genetic Therapies, Inc., Ethris GMBH
    Inventors: Michael Heartlein, Braydon Charles Guild, Frank DeRosa, Carsten Rudolph, Christian Plank, Lianne Smith
  • MRNA THERAPY FOR ARGININOSUCCINATE SYNTHETASE DEFICIENCY
    Publication number: 20150110859
    Abstract: The present invention provides, among other things, methods of treating Argininosuccinate Synthetase Deficiency (ASD), including administering to a subject in need of treatment a composition comprising an mRNA encoding argininosuccinate synthetase (ASS1) at an effective dose and an administration interval such that at least one symptom or feature of ASD is reduced in intensity, severity, or frequency or has delayed in onset.
    Type: Application
    Filed: October 22, 2014
    Publication date: April 23, 2015
    Inventors: Michael Heartlein, Frank DeRosa, Lianne Smith
  • CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES
    Publication number: 20150038556
    Abstract: Materials, formulations, production methods, and methods for delivery of CFTR mRNA for induction of CFTR expression, including in the mammalian lung are provided. The present invention is particularly useful for treating cystic fibrosis.
    Type: Application
    Filed: June 17, 2014
    Publication date: February 5, 2015
    Inventors: Michael Heartlein, Braydon Charles Guild, Frank DeRosa, Carsten Rudolph, Christian Plank, Lianne Smith