Patents by Inventor LIBO ZHAO
LIBO ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240099137Abstract: An alginate hydrogel-based thin-film heat flux sensor for billet crystallizer includes an alginate hydrogel substrate. The alginate hydrogel substrate is configured in a U-shaped planar structure. The U-shaped planar structure includes a first side and a second side, and the first side is longer than the second side. An inner surface of the alginate hydrogel substrate is provided with a first film thermocouple and a second film thermocouple. The first film thermocouple is in crosslinking connection with the second film thermocouple.Type: ApplicationFiled: October 16, 2023Publication date: March 21, 2024Inventors: Zhongkai ZHANG, Jiaming LEI, Le LI, Shuimin LI, Bian TIAN, Libo ZHAO, Zhuangde JIANG
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Patent number: 11686637Abstract: A silicon carbide-based micro-electro-mechanical system (MEMS) combined temperature-pressure sensor chip and a preparation thereof. The chip includes a peripheric pressure-measuring unit and a center temperature-measuring unit. The pressure-measuring unit includes a silicon carbide substrate with a raised island and a pressure sensitive diaphragm formed by etching the back of the substrate. The raised island and the pressure-sensitive diaphragm constitute a membrane-island structure. Four piezoresistive strips are arranged symmetrically along a circumferential direction of a root of the pressure-sensitive diaphragm and between the raised island and the pressure-sensitive diaphragm. The temperature-measuring unit includes the raised island and a thin-film thermocouple arranged thereon.Type: GrantFiled: January 25, 2022Date of Patent: June 27, 2023Assignee: XI'AN JIAOTONG UNIVERSITYInventors: Xudong Fang, Ziyan Fang, Chen Wu, Hao Sun, Libo Zhao, Bian Tian, Zhuangde Jiang, Wubin Deng, Bonan Gao, Junxia Wu, Songli Wang, Nan Zhu
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Publication number: 20230156873Abstract: Disclosed is an electromagnetic-induction heating device for a thin film thermocouple on a ceramic blade, including a spiral coil. The ceramic blade is enveloped in the spiral coil, and two ends of the spiral coil are both connected to an electromagnetic-induction heater. The ceramic blade is arranged in an alumina ceramic chamber, and the thin-film thermocouple is arranged on a surface of the ceramic blade. One end of the air channel is connected to an end of the alumina ceramic chamber, and the other end of the air channel is connected to an infrared nod temperature instrument and a vacuum pump. The infrared nod temperature instrument, the electromagnetic-induction heater, and the vacuum pump controller are electrically connected to the controller.Type: ApplicationFiled: January 4, 2023Publication date: May 18, 2023Inventors: Zhongkai ZHANG, Bian TIAN, Hao LI, Bingfei ZHANG, Libo ZHAO
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Patent number: 11598676Abstract: Provided herein is a tungsten-rhenium composite thin film thermocouple based on a surface micropillar array with gas holes. A tungsten-rhenium thin film thermocouple is arranged on a surface of a flat alumina ceramic substrate. Two tails of the tungsten-rhenium thin film thermocouple are respectively connected to a lead wire. A surface of the tungsten-rhenium thin film thermocouple is arrayed with a plurality of micron alumina micropillars to form an alumina micropillar array. Air is filled between the micron alumina micropillars to form the gas holes. The flat alumina ceramic substrate, the tungsten-rhenium thin film thermocouple and the alumina micropillar array form a three-layered laminated structure.Type: GrantFiled: June 23, 2022Date of Patent: March 7, 2023Assignee: XI'AN JIAOTONG UNIVERSITYInventors: Zhongkai Zhang, Bian Tian, Bingfei Zhang, Jiangjiang Liu, Zhaojun Liu, Libo Zhao
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Publication number: 20220326092Abstract: Provided herein is a tungsten-rhenium composite thin film thermocouple based on a surface micropillar array with gas holes. A tungsten-rhenium thin film thermocouple is arranged on a surface of a flat alumina ceramic substrate. Two tails of the tungsten-rhenium thin film thermocouple are respectively connected to a lead wire. A surface of the tungsten-rhenium thin film thermocouple is arrayed with a plurality of micron alumina micropillars to form an alumina micropillar array. Air is filled between the micron alumina micropillars to form the gas holes. The flat alumina ceramic substrate, the tungsten-rhenium thin film thermocouple and the alumina micropillar array form a three-layered laminated structure.Type: ApplicationFiled: June 23, 2022Publication date: October 13, 2022Inventors: Zhongkai ZHANG, Bian TIAN, Bingfei ZHANG, Jiangjiang LIU, Zhaojun LIU, Libo ZHAO
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Publication number: 20220146352Abstract: A silicon carbide-based micro-electro-mechanical system (MEMS) combined temperature-pressure sensor chip and a preparation thereof. The chip includes a peripheric pressure-measuring unit and a center temperature-measuring unit. The pressure-measuring unit includes a silicon carbide substrate with a raised island and a pressure sensitive diaphragm formed by etching the back of the substrate. The raised island and the pressure-sensitive diaphragm constitute a membrane-island structure. Four piezoresistive strips are arranged symmetrically along a circumferential direction of a root of the pressure-sensitive diaphragm and between the raised island and the pressure-sensitive diaphragm. The temperature-measuring unit includes the raised island and a thin-film thermocouple arranged thereon.Type: ApplicationFiled: January 25, 2022Publication date: May 12, 2022Inventors: Xudong FANG, Ziyan FANG, Chen WU, Hao SUN, Libo ZHAO, Bian TIAN, Zhuangde JIANG, Wubin DENG, Bonan GAO, Junxia WU, Songli WANG, Nan ZHU
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Patent number: 10634587Abstract: A system for isolating preselected cell types from a fluid sample that includes a plurality of cell types includes a cell-capture fluidic chip, and a chip holder configured to receive the cell-capture fluidic chip and to maintain the cell-capture fluidic chip with a substantially fluid-tight seal while in operation. The chip holder is further configured to release the cell-capture fluidic chip to be removed from the chip holder for further processing. The cell-capture fluidic chip includes a substrate, a laser micro-dissection membrane disposed on the substrate, and a channel-defining layer disposed on the laser micro-dissection membrane. The laser micro-dissection membrane has a surface adapted to capture preselected cell types preferentially over other cell types of the plurality of cell types. The channel-defining layer is removable from the laser micro-dissection membrane for further processing of the cell-capture fluidic chip.Type: GrantFiled: April 9, 2018Date of Patent: April 28, 2020Assignee: The Regents of the University of CaliforniaInventors: Hsian-Rong Tseng, Mitch A. Garcia, Min Song, Libo Zhao, Shuang Hou, Tom Lee
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Patent number: 10444233Abstract: A device for capturing preselected cell types from a fluid sample that includes a plurality of cell types includes a substrate, a plurality of nanowires at least one of attached to or integral with a surface of the substrate such that each nanowire of the plurality of nanowires has an unattached end, and a layer of temperature-responsive material formed on at least the unattached end of each of the plurality of nanowires. The layer of temperature-responsive material has a compact configuration at a first temperature and an expanded configuration at a second temperature so as to facilitate release of cells captured at the first temperature to be released at the second temperature.Type: GrantFiled: July 31, 2013Date of Patent: October 15, 2019Assignees: The Regents of the University of California, RikenInventors: Hsian-Rong Tseng, Shuang Hou, Libo Zhao, Hsiao-Hua Yu, Shyh-Chyang Luo, Haichao Zhao
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Publication number: 20180231441Abstract: A system for isolating preselected cell types from a fluid sample that includes a plurality of cell types includes a cell-capture fluidic chip, and a chip holder configured to receive the cell-capture fluidic chip and to maintain the cell-capture fluidic chip with a substantially fluid-tight seal while in operation. The chip holder is further configured to release the cell-capture fluidic chip to be removed from the chip holder for further processing. The cell-capture fluidic chip includes a substrate, a laser micro-dissection membrane disposed on the substrate, and a channel-defining layer disposed on the laser micro-dissection membrane. The laser micro-dissection membrane has a surface adapted to capture preselected cell types preferentially over other cell types of the plurality of cell types. The channel-defining layer is removable from the laser micro-dissection membrane for further processing of the cell-capture fluidic chip.Type: ApplicationFiled: April 9, 2018Publication date: August 16, 2018Applicant: The Regents of the University of CaliforniaInventors: Hsian-Rong Tseng, Mitch A. Garcia, Min Song, Libo Zhao, Shuang Hou, Tom Lee
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Patent number: 9228929Abstract: The present invention provides a method of on-line rapid fluid density measurement using a piezoresistive micro-cantilever, the present invention can achieve on-line measurement without changing the existing device; more importantly, without acquiring the resonant frequency of the cantilever in fluid to be detected, thus remarkably reducing measurement time, and guaranteeing the real on-line rapid measurement. By using the method of the present invention, measurement of the density of fluid to be detected by a calibrated piezoresistive micro-cantilever may be achieved within seconds or even shorter.Type: GrantFiled: October 23, 2012Date of Patent: January 5, 2016Assignee: XI'AN JIAOTONG UNIVERSITYInventors: Zhuangde Jiang, Guiming Zhang, Libo Zhao, Enze Huang, Longqi Xu, Yulong Zhao, Xiaopo Wang, Bo Song, Zhigang Liu
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Publication number: 20150285717Abstract: A system for isolating preselected cell types from a fluid sample that includes a plurality of cell types includes a cell-capture fluidic chip, and a chip holder configured to receive the cell-capture fluidic chip and to maintain the cell-capture fluidic chip with a substantially fluid-tight seal while in operation. The chip holder is further configured to release the cell-capture fluidic chip to be removed from the chip holder for further processing. The cell-capture fluidic chip includes a substrate, a laser micro-dissection membrane disposed on the substrate, and a channel-defining layer disposed on the laser micro-dissection membrane. The laser micro-dissection membrane has a surface adapted to capture preselected cell types preferentially over other cell types of the plurality of cell types. The channel-defining layer is removable from the laser micro-dissection membrane for further processing of the cell-capture fluidic chip.Type: ApplicationFiled: May 29, 2013Publication date: October 8, 2015Applicants: The Regents of the University of California, CytoLumina Technologies Corp, Inc.Inventors: Hsian-Rong Tseng, Mitch A. Garcia, Min Song, Libo Zhao, Shuang Hou, Tom Lee, Daniel Wang, Bo Tao
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Publication number: 20150260710Abstract: A device for capturing preselected cell types from a fluid sample that includes a plurality of cell types includes a substrate, a plurality of nanowires at least one of attached to or integral with a surface of the substrate such that each nanowire of the plurality of nanowires has an unattached end, and a layer of temperature-responsive material formed on at least the unattached end of each of the plurality of nanowires. The layer of temperature-responsive material has a compact configuration at a first temperature and an expanded configuration at a second temperature so as to facilitate release of cells captured at the first temperature to be released at the second temperature.Type: ApplicationFiled: July 31, 2013Publication date: September 17, 2015Inventors: Hsian-Rong Tseng, Shuang Hou, Libo Zhao, Hsiao-Hua Yu, Shyh-Chyang Luo, Haichao Zhao
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Publication number: 20150111787Abstract: Described herein is a digital microfluidic droplet generator (DMDG) and a microfluidic platform for processing material introduced into the DMDG. The combination is particularly suited for hydrogen/deuterium exchange and mass spectrometer (HDX-MS) processing and analysis of membrane proteins.Type: ApplicationFiled: June 4, 2012Publication date: April 23, 2015Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Kwang-Fu C. Shen, Julian P. Whitelegge, Kym Francis Faull, Libo Zhao, Christopher Miles Ryan
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Publication number: 20130261995Abstract: The present invention provides a method of on-line rapid fluid density measurement using a piezoresistive micro-cantilever, the present invention can achieve on-line measurement without changing the existing device; more importantly, without acquiring the resonant frequency of the cantilever in fluid to be detected, thus remarkably reducing measurement time, and guaranteeing the real on-line rapid measurement. By using the method of the present invention, measurement of the density of fluid to be detected by a calibrated piezoresistive micro-cantilever may be achieved within seconds or even shorter.Type: ApplicationFiled: October 23, 2012Publication date: October 3, 2013Applicant: XI'AN JIAOTONG UNIVERSITYInventors: ZHUANGDE JIANG, GUIMING ZHANG, LIBO ZHAO, ENZE HUANG, LONGQI XU, YULONG ZHAO, XIAOPO WANG, BO SONG, ZHIGANG LIU