Publication number: 20150072953
Abstract: The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.
Type:
Application
Filed:
June 16, 2014
Publication date:
March 12, 2015
Inventors:
Lidia Alfaro Brownell, Min Chu, Mei-Feng Hong, Eu-Jin Hyun, Qi Jia, Ping Jiao, Hyun-Jin Kim, Mi-Ran Kim, Tae-Woo Kim, Bo-Su Lee, Young-Chul Lee, Breanna Moore, Jeong-Bum Nam, Mi-Sun Oh, Mi-Hye Park, Mesfin Yimam, Qian Zhang
Publication number: 20140004215
Abstract: The present disclosure provides Diels-Alder adducts of chalcone and prenylphenyl moieties capable of modulating the activity of cannabinoid receptors, and to oligomers of flavan-3-ol capable of modulating fat absorption and storage. Such Diels-Alder adducts of chalcone and prenylphenyl moieties or oligomers of flavan-3-ol can optionally be used in combination with other weight management agents, such as anorectic agents, a lipase inhibitors, other cannabinoid receptor modulators, psychotropic agents, insulin sensitizers, stimulants, or satiety agents, as well as to methods of use thereof such as treating or preventing weight gain or obesity, promoting weight loss, appetite suppression, modifying satiety, or the like.
Type:
Application
Filed:
May 29, 2013
Publication date:
January 2, 2014
Applicants:
Unigen, Inc., UNIGEN, INC.
Inventors:
Lidia Alfaro BROWNELL, Byong-Il CHOI, Brandon CORNELIUSEN, Mei-Feng HONG, Eu-Jin HYUN, Qi JIA, Ping JIAO, Hyun-Jin KIM, Mi-Ran KIM, Tae-Woo KIM, Bo-Su LEE, Young-Chul LEE, Jeong-Bum NAM, Mesfin YIMAN, Ji-Hye Hwang, Mi-Sun OH