Abstract: This invention pertains to a class of autophagy inducing compounds that treat diseases caused by misfolded protein aggregates and a screening method for identifying these compounds.

Abstract: An integrated filter assembly is provided. The filter assembly includes a fastener that holds two substantially opposing elements of a housing together. Also included is a multi-purpose filter that has at least a particle filter component and a chemical filter component. The multi-purpose filter is attached to the fastener. The multi-purpose filter is within the housing when the fastener holds the two substantially opposing elements of the housing together.

Abstract: A data storage system includes a housing, one or more data storage media disposed within the housing, and an filter comprising activated carbon fibers disposed within the housing. The activated carbon fiber filter includes activated carbon fibers configured to adsorb both chemical contaminants and particulate contaminants within the housing. The activated carbon fiber filter may include a wide variety of active molecular functional groups, pores with sizes from macroscopic to nanoscopic scales, and a very high surface area per unit mass, in various embodiments. The activated carbon fiber filter may be mounted in a region of the data storage system having enhanced fluid pressure when the data storage system is in normal operation.

Abstract: The present invention provides a method for increasing storage capacity of a disc drive by physically skewing a transducer in relation to a slider supporting the transducer. The physical skew angle of the transducer is configured to provide a predetermined zero skew position on the medium, which is capable of providing an increased storage capacity to the medium. To ascertain this zero skew position, a storage density or storage capacity of the medium may be ascertained for each of various zero skew positions on the medium. A desired storage density or capacity level is selected according to storage capacity requirements and the corresponding zero skew position is ascertained. The corresponding zero skew position may be implemented by physically skewing a transducer relative to a slider.

Abstract: An integrated filter assembly is provided. The filter assembly includes a fastener that holds two substantially opposing elements of a housing together. Also included is a multi-purpose filter that has at least a particle filter component and a chemical filter component. The multi-purpose filter is attached to the fastener. The multi-purpose filter is within the housing when the fastener holds the two substantially opposing elements of the housing together.

Abstract: A disc drive utilizes ramp load unload technology. A ramp component of the disc drive includes a recess that reduces the contact surface area of the ramp component that supports an actuator assembly to unload a slider of the disc drive. The actuator assembly may include a lift tab that interacts with the ramp component to hold the slider off a media disc when the slider is unloaded.

Abstract: A data storage system includes a housing, one or more data storage media disposed within the housing, and an filter comprising activated carbon fibers disposed within the housing. The activated carbon fiber filter includes activated carbon fibers configured to adsorb both chemical contaminants and particulate contaminants within the housing. The activated carbon fiber filter may include a wide variety of active molecular functional groups, pores with sizes from macroscopic to nanoscopic scales, and a very high surface area per unit mass, in various embodiments. The activated carbon fiber filter may be mounted in a region of the data storage system having enhanced fluid pressure when the data storage system is in normal operation.

Abstract: A preform used for producing an optical fiber fixing member having an optical fiber fixing part and a lower-staged part by a mold shaping method, is formed so as to be composed of a large-thickness portion having an upper surface or a peak portion to which that transfer-shaping surface of transfer-shaping surfaces of a shaping mold which is to shape the said optical fiber fitting portion(s) comes into contact at an initial stage of mold shaping, and a small-thickness portion having an upper surface or a peak portion to which that transfer-shaping surface of transfer-shaping surfaces of the shaping mold which is to shape the upper surface of the lower-staged part comes into contact at an initial stage of the mold shaping, the preform being formed in a configuration in which the said small-thickness portion is adjacent to the large-thickness portion, the form of the preform viewed as a plan view parallels with the form of the said optical fiber fixing member viewed as a plan view and the form of the preform vie

Abstract: In a method for molding glass products having a fine structure as of an optical fiber holder with a high size precision, a mold used for the molding has the fine structure in a size such that a size difference occurring when the glass product is cooled down to a room temperature where at the end of molding with a pressure a size of the fine structure of the mold for glass product and a size of a fine structure of the glass product formed by transfer of the fine structure of the mold are the same as one another is so adjusted that a size of the fine structure of the completed glass product falls within a permissive size precision range. The mold may has a size satisfying, as a size of a fine structure at a room temperature, a formula [1+(.alpha.g-.alpha.m).times..DELTA.T+.alpha.g'.times..DELTA.T'].times.Sg, wherein Sg denotes a size of a fine structure of thc glass product at the room temperature; .alpha.

Abstract: A manufacturing method for a glass product not having a rotatively symmetric body like an optical fiber fixing member but having a fine structure as of optical fiber engagement portions, to transfer the fine structure with a high precision without creating molding burrs, includes the steps of placing a glass material in a cavity defined by a lower mold, an upper mold, and a side mold, molding the glass material in the cavity with pressure into the glass product in so controlling that the glass material has a viscosity range of 10.sup.6.5 to 10.sup.9.

Abstract: A superconductor wire comprising an inner core and an outer ring covering the core, wherein one of the inner core and the outer ring comprises a sintered silver powder and the other of the inner core and the outer ring on the core comprises a sintered oxide superconductor powder.

Abstract: A process for production of superconductor wire having multiple rings, comprising the steps of: preparing a silver mixture comprising a silver or silver-gold alloy mixed with a bonding agent, and a superconductor mixture comprising a superconductor powder with bonding agent; arranging both the silver mixture and the superconductor mixture in a extrusion die; extruding a wire having at least one ring of the superconductor mixture and one ring of the silver mixture in the radial direction; and heating the wire at the sinter temperature of the oxide superconductor so that the bonding agent is removed and the oxide superconductor powder and the silver powder are sintered. A superconductor wire comprising an inner core and an outer ring covering the core, wherein one of the ring on the core comprises a sintered silver powder and the other of the ring on the core comprises a sintered oxide superconductor powder.