Abstract: Disclosed are a pyrimidine-fused cyclic compound having an inhibitory effect on KRAS gene mutation, or a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating cancer.

Abstract: This application relates to the field of network security technologies, and provides an access control method, an access control system, and a related device, to improve security of a protected application resource. The method includes: An SDP controller receives a first packet sent by a first SDP client device, where a TCP option field of the first packet carries a device identifier of the first SDP client device. The SDP controller performs single-packet authentication on the first SDP client device based on the device identifier of the first SDP client device. If the single-packet authentication on the first SDP client device fails, the SDP controller disables a TCP connection between the first SDP client device to which the first packet belongs and the SDP controller.

Abstract: Provided are a user feature-based page displaying method and apparatus, a medium and an electronic device. When performing product recommendation to a user, label data representing a feature of the user is acquired; a similarity between the user and each user group of a plurality of user groups obtained in advance is calculated according to the label data; then, based on the similarity, one or more target user groups having the highest similarity to the user is selected from the plurality of user groups; and then page modules corresponding to these target user groups are acquired; then, on a recommendation page displayed to the user, product information is recommend through these page modules respectively, where each page module clusters products having one attribute.

Abstract: The invention relates to a bailer that includes a leak-free, novel check valve assembly and a complemental flow-controlling release nozzle. The check valve is guided and confined to the valve housing and is configured with a contour rubber O-ring so that an airtight seal can be achieved when valve is closed. The release nozzle is designed to gradually open and close the check valve. Users thus are able to achieve desired sample outflows by turning the release nozzle just as using a faucet.

Abstract: A control interface for accessing a plurality of systems of a vehicle, comprising: a first control interface disposed on a surface of a steering wheel; a second control interface disposed on a surface of a steering wheel, the second control interface being positioned remote from the first control interface; a visual display disposed within the vehicle, wherein the first control interface provides access to a vehicle system and the second control interface provides a means for modifying the state of the vehicle system access by the first control interface.