Patents by Inventor Likun Liu

Likun Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240189443
    Abstract: Disclosed in the present invention are a use of a combination of an anti-PD-L1 nanobody and a TLR7 small molecule agonist in anti-tumor treatment, and a PD-L1 and TLR7 double-targeting nanobody coupling drug, a preparation method therefor, and a use thereof. Specifically, disclosed in the present invention are a use and solution of a combination of an anti-PD-L1 nanobody and a derived protein thereof as well as a TLR7 small molecule agonist and a derived compound thereof in anti-tumor treatment. Meanwhile, disclosed in the present invention are design, preparation, and identification solutions for a novel PD-L1 and TLR7 double-targeting-nanobody drug conjugate and a derived molecule thereof, and an effect of the novel PD-L1 and TLR7 double-targeting nanobody drug conjugate in anti-tumor treatment. The PD-L1 and TLR7 double-targeting nanobody drug conjugate of the present invention can yield a significant antineoplastic efficacy in various transplantation tumor models.
    Type: Application
    Filed: March 15, 2022
    Publication date: June 13, 2024
    Inventors: Likun GONG, Xiaolu YU, Yiru LONG, Jianhua SUN, Yongliang TONG, Tingting LIU
  • Patent number: 12003166
    Abstract: Disclosed is a device with a stator and a rotor, the device comprising: a stator; a rotor, wherein an air gap is provided between the rotor and the stator; and an air gap protection device fixedly connected to the stator, wherein the radial distance between the air gap protection device and the rotor is less than the radial distance between the stator and the rotor, and the air gap protection device rotates relative to the rotor when in contact with the rotor. By arranging the air gap protection device fixedly connected to the stator, the air gap protection device can rotate relative to the rotor when in contact with the rotor, and the radial distance between the air gap protection device and the rotor is less than the radial distance between the stator and the rotor.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: June 4, 2024
    Assignee: XINJIANG GOLDWIND SCIENCE & TECHNOLOGY CO., LTD.
    Inventors: Likun Liu, Yanhui Li, Liang Peng
  • Publication number: 20240166951
    Abstract: A continuous solid organic matter pyrolysis polygeneration system and method for using the system is disclosed. The pyrolysis polygeneration system mainly includes a processing system, a drying furnace, a pyrolysis furnace, a cooling furnace, a tail gas treatment system, and a gas treatment system and a protective gas circulation system cooperate with each other to realize the multi-level rational utilization of energy, and are suitable for the continuous and rapid pyrolysis and carbonization of various solid organic matter in the actual production. While realizing the polygeneration of coke, wood vinegar and tar, the maximum utilization of overall heat is realized through process optimization.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 23, 2024
    Inventors: Hongyu SI, Bing WANG, Xiaohui LIANG, Suxiang LIU, Meirong XU, Yonggang LI, Zhaojie CUI, Qiang YAO, Haichao WANG, Laizhi SUN, Shuangxia YANG, Likun HE, Dongliang HUA, Zhijie GU
  • Publication number: 20240152075
    Abstract: The present disclosure provides a toner cartridge, detachably installed in an electronic image-forming apparatus. The electronic image-forming apparatus includes a developer replenishing apparatus; the developer replenishing apparatus includes a developer receiving portion; the developer receiving portion includes a receiving opening; and the receiving opening is disposed with a blocking piece for sealing the receiving opening. The toner cartridge includes a toner cartridge body configured to store developer; and a toner outlet structure connected to a toner outlet end of the toner cartridge body and configured to discharge the developer in the toner cartridge body.
    Type: Application
    Filed: January 16, 2024
    Publication date: May 9, 2024
    Inventors: Xinyu WU, Likun ZENG, Qijie LIANG, Wenjun YU, Mengyuan LIU
  • Publication number: 20220407386
    Abstract: Disclosed is a device with a stator and a rotor, the device comprising: a stator; a rotor, wherein an air gap is provided between the rotor and the stator, and an air gap protection device fixedly connected to the stator, wherein the radial distance between the air gap protection device and the rotor is less than the radial distance between thy stator and the rotor, and the air gap protection device rotates relative to the rotor when in contact with the rotor. By arranging the air gap protection device fixedly connected to the stator, the air gap protection device can rotate relative to the rotor when in contact with the rotor, and the radial distance between the air gap protection device and the rotor is less than the radial distance between the stator and the rotor.
    Type: Application
    Filed: June 4, 2020
    Publication date: December 22, 2022
    Inventors: Likun LIU, Yanhui LI, Liang PENG
  • Publication number: 20220200381
    Abstract: The present disclosure relates to a rotor of a motor, a method for maintaining the rotor of the motor, the motor and a wind-power electric generator set. The rotor of the motor includes a magnetic yoke, in which the magnetic yoke is in a cylindrical-like shape, and the magnetic yoke is configured to fix a magnet on its circumference surface; and a rotor support, including a shaft connection unit and a supporting ring, in which the shaft connection unit is coaxially connectable to a rotation shaft of a motor, the supporting ring is arranged on an outer periphery of the shaft connection unit, and the magnetic yoke is connected to the supporting ring; herein, at least one of the magnetic yoke and the supporting ring of the rotor support has a structure divided into a plurality of segments in a circumference direction of itself.
    Type: Application
    Filed: February 7, 2020
    Publication date: June 23, 2022
    Inventors: Likun LIU, Yanhui LI
  • Publication number: 20200142985
    Abstract: The disclosed embodiments relate to a system that publishes an event to a message bus in an event-driven computing system. During operation, the system executes event-producing code, which detects an event, wherein the event results in one or more writes to a database system, and wherein success of the one or more writes defines whether the event took place. In response to detecting the event, the system writes the event to temporary storage, which is maintained by the database system, wherein the database system automatically reclaims the temporary storage without requiring additional clean up operations by the application. Next, the system executes event-publishing code, which asynchronously collects the event from the temporary storage, and publishes the event to the message bus.
    Type: Application
    Filed: November 7, 2018
    Publication date: May 7, 2020
    Applicant: Zendesk, Inc.
    Inventor: Likun Liu
  • Publication number: 20080048069
    Abstract: The present invention relates to a vibration attenuation/isolation device. An implementation of the invention provides an improved whole-spacecraft vibration attenuation/isolation by separating the vibration load on the spacecraft that arise from the launch vehicle and fairing into longitudinal and lateral components, and effectively attenuates and/or isolates those components. The invention also provides a general method for reducing vibrations in an assembly by using a vibration control device that separates the vibrational forces into perpendicular components that can be separately damped or attenuated.
    Type: Application
    Filed: November 16, 2006
    Publication date: February 28, 2008
    Inventors: Gangtie Zheng, Likun Liu, Lu Liang, Ling He