Patents by Inventor Lilia Maria Babe

Lilia Maria Babe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11384348
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus gibsonii, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: July 12, 2022
    Assignee: DANISCO US INC
    Inventors: Marc Kolkman, Frits Goedegebuur, Lilia Maria Babe, Rie Mejldal, Harm Mulder, Anja Hemmingsen Kellett-Smith, Richard R Bott, Miles Christopher Scotcher
  • Publication number: 20220098524
    Abstract: A phosphate-free automatic dishwashing cleaning composition including: a) a protease wherein the protease is a variant having at least 60% identity with the amino acid sequence of SEQ ID NO:1 or SEQ ID NO:2 including two negatively charged amino acid residues, aspartic acid (D) and/or glutamic acid (E), in positions 124-131 using the SEQ ID NO: 1 numbering and the SEQ ID NO:2, respectively; and b) from 10 to 50% by weight of the composition of a complexing agent system comprising from 0 to less than 30% by weight of the composition of citric acid.
    Type: Application
    Filed: October 22, 2021
    Publication date: March 31, 2022
    Inventors: Philip Frank SOUTER, Eva Maria PEREZ-PRAT de VINUESA, Lilia Maria BABE, David Aaron ESTELL, Frits GOEDEGEBUUR, Harm Jan MULDER, Sina PRICELIUS, Lydia DANKMEYER, Thijs KAPER, Hatice Billur ENGIN
  • Patent number: 11220656
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: January 11, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Frits Goedegebuur, David Aaron Estell, Lilia Maria Babe, Thijs Kaper, Viktor Alekseyev, Sina Pricelius, Hatice Billur Engin, Harm Jan Mulder, Sander Van Stigt-Thans, Eva Maria Perez-Prat Vinuesa
  • Publication number: 20210395715
    Abstract: The present disclosure relates to serine proteases and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: June 2, 2021
    Publication date: December 23, 2021
    Inventors: Marc Kolkman, Rie Mejldal, Anja Hemmingsen Kellett-Smith, Lilia Maria Babe
  • Publication number: 20210363470
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: May 24, 2019
    Publication date: November 25, 2021
    Inventors: Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Billur H. ENGIN, David A. ESTELL, Frits GOEDEGEBUUR, Thijs KAPER, Harm MULDER, Sina PRICELIUS, Sander Van Stigt THANS
  • Publication number: 20210292728
    Abstract: Disclosed herein is one or more subtilisin variant useful for cleaning applications and in methods of cleaning. One embodiment is directed to one or more subtilisin variant, including one or more Bacillus sp. subtilisin polypeptide variant, and one or more cleaning composition comprising one or more such variant.
    Type: Application
    Filed: March 30, 2021
    Publication date: September 23, 2021
    Inventors: LILIA MARIA BABE, VIKTOR YURYEVICH ALEKSEYEV, NEELAM S. AMIN, JOSHUA ROY BASLER, DAVID A. ESTELL, VICTORIA HUANG, DAVID MARQUEZ, JEFFREY WAYNE MUNOS, REI OTSUKA, GEETHA VEERAMUTHU, DAVID EDWARD WILDES, MICHELLE JACKSON, EUAN JOHN MAGENNIS, EVA MARIA PEREZ-PRAT VINUESA, PHILIP F. SOUTER, DAVID JOHN TARBIT
  • Publication number: 20210214703
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: May 24, 2019
    Publication date: July 15, 2021
    Inventors: Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Billur H. ENGIN, David A. ESTELL, Frits GOEDEGEBUUR, Thijs KAPER, Harm MULDER, Sina PRICELIUS, Sander Van Stigt THANS
  • Patent number: 11008559
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus Akibai and Bacillus Clarkii, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: May 18, 2021
    Assignee: DANISCO US INC
    Inventors: Marc Kolkman, Rie Mejldal, Anja Hemmingsen Kellett Smith, Lilia Maria Babe, Richard R. Bott
  • Publication number: 20210122997
    Abstract: A phosphate-free automatic dishwashing cleaning composition comprising a protease wherein the protease has at least 80%, preferably at least 85%, more preferably at least 90% and especially at least 96% identity with the amino acid sequence of SEQ ID NO:1 or with the amino acid sequence of SEQ ID NO:2 and wherein the protease comprises amino acid substitutions selected from the group consisting of: (i) at least two amino acid substitutions selected from the group consisting of: X198G/A/K/L/Q/R/T/V/S/L, X207Q, X211Q/N and X212Q in combination with at least three amino acid substitutions selected from the group consisting of: X039E, X074D, X099R, X126A, X127E and X128G; or (ii) X039E-X074D-X099R-X116R-X126A-X127E-X128G-X211Q; X039E-X074D-X099R-X126A-X127E-X128G-X211N; X039E-X074D-X099R-X126A-X127E-X128G-X211Q; X039E-X074D-X099R-X126A-X127E-X128G-X207Q; or (iii) any of the proteases of (i) and (ii) further comprising at least one amino acid substitution selected from X242D and X256E; or (iv) X039E-X074D-X099R
    Type: Application
    Filed: October 9, 2020
    Publication date: April 29, 2021
    Inventors: Philip Frank SOUTER, Eva Maria PEREZ-PRAT VINUESA, Michelle JACKSON, Carly PICKERING, Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Frits GOEDEGEBUUR, Thijs KAPER, Sina PRICELIUS, Sander VAN STIGT THANS, Harm MULDER, Nils Henning REDESTIG, Lydia DANKMEYER, Michael STONER, Adam GARSKE, Roopa Santosh GHIRNIKAR
  • Patent number: 10913919
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: February 9, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Frits Goedegebuur, David Aaron Estell, Lilia Maria Babe, Thijs Kaper, Viktor Alekseyev, Sina Pricelius, Hatice Billur Engin, Harm Jan Mulder, Sander Van Stigt-Thans, Eva Maria Perez-Prat Vinuesa
  • Publication number: 20200392477
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: December 19, 2017
    Publication date: December 17, 2020
    Inventors: Lilia Maria Babe, Lydia Dankmeyer, David A. Estell, Frits Goedegebuur, Thijs Kaper, Harm Mulder, Sina Pricelius
  • Publication number: 20200369987
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Application
    Filed: May 18, 2020
    Publication date: November 26, 2020
    Inventors: Lilia Maria BABE, Frits (NMN) GOEDEGEBUUR, Thijs KAPER, Sina PRICELIUS, Eva Maria PEREZ-PRAT VINUESA, Michelle JACKSON, Carly PICKERING, Philip Frank SOUTER
  • Publication number: 20200362326
    Abstract: The present disclosure relates to serine proteases and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: January 27, 2020
    Publication date: November 19, 2020
    Inventors: Marc Kolkman, Anja Hemmingsen Kellett-Smith, Rie Mejldal, Lilia Maria Babe
  • Publication number: 20200354708
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability compared to one or more reference subtilisin.
    Type: Application
    Filed: November 28, 2018
    Publication date: November 12, 2020
    Inventors: Lilia Maria Babe, Viktor Yuryevich Alekseyev, Joshua Roy Basler, H. Billur Engin, David A. Estell, Roopa Santosh Ghirnikar, Frits Goedegebuur, Thijs Kaper, Mulder Harm, Sina Pricelius, Thans Sander Van Stigt
  • Publication number: 20200332229
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: May 31, 2017
    Publication date: October 22, 2020
    Applicant: Danisco US Inc.
    Inventors: David MARQUEZ, Michael STONER, James T. KELLIS, JR., Adam GARSKE, Joshua Roy BASLER, Katherine AUGUSTYN, Priyanka CHANDRASEKARAN, Miles Christopher SCOTCHER, Lilia Maria BABE, Richard R. BOTT, David A. ESTELL, Gudrun VOGTENTANZ, Sina PRICELIUS, Jian YAO
  • Publication number: 20200248160
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus gibsonii, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: December 4, 2019
    Publication date: August 6, 2020
    Inventors: MARC KOLKMAN, FRITS GOEDEGEBUUR, LILIA MARIA BABE, RIE MEJLDAL, HARM MULDER, ANJA HEMMINGSEN KELLETT-SMITH, RICHARD R BOTT, MILES CHRISTOPHER SCOTCHER
  • Patent number: 10731144
    Abstract: The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include polynucleotides encoding serine protease sequences with modified or heterologous propeptide regions; polypeptides comprising serine proteases with modified or heterologous propeptide regions; expression cassettes, DNA constructs, vectors, and chromosomes comprising such polynucleotides; and bacterial host cells comprising such polynucleotides. The methods include methods for enhancing the production of mature proteases in bacterial host cells (e.g. Bacillus sp. host cells). The produced proteases find use in the industrial production of enzymes, suitable for use in various industries, including but not limited to the cleaning, animal feed and textile processing industry.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: August 4, 2020
    Assignee: DANISCO US INC
    Inventors: Lilia Maria Babe, Carol Marie Fioresi, Frits Goedegebuur, Harm Mulder
  • Publication number: 20200239814
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus spp., and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: November 7, 2019
    Publication date: July 30, 2020
    Inventors: Marc Kolkman, Anja Hemmingsen Kellett-Smith, Rie Mejldal, Lilia Maria Babe
  • Publication number: 20200172837
    Abstract: The present disclosure relates to serine proteases and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: August 6, 2019
    Publication date: June 4, 2020
    Inventors: Marc Kolkman, Frits Goedegebuur, Harm Mulder, Lilia Maria Babe
  • Publication number: 20200123522
    Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.
    Type: Application
    Filed: December 19, 2019
    Publication date: April 23, 2020
    Inventors: David A Estell, Frits Goedegebuur, Marc Anton Bernhard Kolkman, Rie Mejldal, Katherine Augustyn, Lilia Maria Babe, Richard R Bott, Jian Yao, Roopa Santosh Ghirnikar