Patents by Inventor Liliane Halab

Liliane Halab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for the treatment or prevention of infections
    Patent number: 8829030
    Abstract: Compounds represented by formula: Wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: September 9, 2014
    Assignee: Vertex Pharmaceuticals (Canada) Incorporated
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thunkunta Jagadeeswar Reddy, Ming Qiang Zhang
  • C-21-keto lupane derivatives preparation and use thereof
    Patent number: 8431556
    Abstract: The invention relates to 21-keto triterpene compounds of formula (I): wherein R1, X and Y are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infections by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.
    Type: Grant
    Filed: July 3, 2010
    Date of Patent: April 30, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Christophe Moinet, Marc Courchesne, Liliane Halab, Nathalie Chauret, Laval Chan Chun Kong
  • Compounds and methods for the treatment or prevention of flavivirus infections
    Patent number: 8357718
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: January 22, 2013
    Assignee: Vertex Pharmaceuticals (Canada) Incorporated
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thumkunta Jagadeeswar Reddy, Zhang Ming-Qiang
  • Lupane derivatives useful for treating HIV
    Patent number: 8269026
    Abstract: The invention relates to 21-keto triterpene compounds of formula (I): wherein R1, X, and Y are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infections by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.
    Type: Grant
    Filed: July 3, 2010
    Date of Patent: September 18, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Christophe Moinet, Liliane Halab, Nathalie Turcotte, Monica Bubenik, Marc Courchesne, Carl Poisson, Oswy Z. Pereira, Paul Nguyen-Ba, Bingcan Liu, Nathalie Chauret, Caroline Cadilhac, Laval Chan Chun Kong
  • NOVEL 17 BETA LUPANE DERIVATIVES
    Publication number: 20110077251
    Abstract: The invention relates to 17? lupane derivatives of formula (I): wherein R1 and X are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infection by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.
    Type: Application
    Filed: August 16, 2010
    Publication date: March 31, 2011
    Inventors: Christophe Moinet, Bingcan Liu, Liliane Halab, Nathalie Turcotte, Real Denis, Carl Poisson, Paul Nguyen-Ba, Monica Bubenik, Laval Chan Chun Kong
  • NOVEL LUPANE DERIVATIVES
    Publication number: 20110077227
    Abstract: The invention relates to 21-keto triterpene compounds of formula (I): wherein R1, X, and Y are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infections by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.
    Type: Application
    Filed: July 3, 2010
    Publication date: March 31, 2011
    Inventors: Christophe Moinet, Liliane Halab, Nathalie Turcotte, Monica Bubenik, Marc Courchesne, Carl Poisson, Oswy Z. Pereira, Paul Nguyen-Ba, Bingcan Liu, Nathalie Chauret, Caroline Cadilhac, Laval Chan Chun Kong
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Publication number: 20080269481
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Application
    Filed: February 4, 2008
    Publication date: October 30, 2008
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Z. Pereira, Carl Poisson, Melaine Proulx, Thumkunta Jagadeeswar Reddy, Zhang Ming-Qiang
  • Compounds and methods for the treatment or prevention of infections
    Patent number: 7402608
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: July 22, 2008
    Assignee: ViroChem Pharma Inc.
    Inventors: Laval Chan Chun Kong, Sanjoy Kumar Das, Nghe Nguyen-Ba, Liliane Halab, Oswy Z. Pereira, Carl Poisson, Melanie Proulx, Thumkunta Jagadeeswar Reddy, Zhang Ming-Qiang
  • Pyridine carboxamide and methods for inhibiting HIV integrase
    Publication number: 20050176767
    Abstract: Compounds of formula I: wherein R1, R2, R4, R10, R11, and Q are as defined herein, and their pharmaceutically acceptable salts, are useful in the prevention or treatment of HIV infections.
    Type: Application
    Filed: October 29, 2004
    Publication date: August 11, 2005
    Inventors: Laval Chan Chun Kong, Ming-Qiang Zhang, Liliane Halab, Nghe Nguyen-Ba, Bingcan Liu
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Publication number: 20050009804
    Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
    Type: Application
    Filed: December 9, 2003
    Publication date: January 13, 2005
    Inventors: Laval Chan Chun Kong, Sanjoy Das, Nghe Nguyen-Ba, Liliane Halab, Bettina Hamelin, Oswy Pereira, Carl Poisson, Melanie Proulx, Thumkunta Reddy, Zhang Ming-Qiang
  • Compounds and methods for the treatment or prevention of Flavivirus infections
    Publication number: 20040192707
    Abstract: Compounds represented by formula I: 1
    Type: Application
    Filed: December 9, 2003
    Publication date: September 30, 2004
    Inventors: Laval Chan Chun Kong, Oswy Z. Pereira, Nghe Nguyen-Ba, Ming-Qiang Zhang, Sanjoy Kumar Das, Carl Poisson, Thumkunta Jagadeeswar Reddy, Liliane Halab